Abstract:
:We studied properties of bacterial biofilms during long-term culturing. The biofilms were preserved for more than 90 days under the chosen conditions. At the same time, amounts of matrix and cells underwent periodic changes. The biomass of the biofilms decreased approximately every 7 days and then returned to the previous values.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Tetz GV,Artemenko NK,Zaslavskaya NV,Tetz VVdoi
10.1007/s10517-013-2180-7subject
Has Abstractpub_date
2013-08-01 00:00:00pages
467-9issue
4eissn
0007-4888issn
1573-8221journal_volume
155pub_type
杂志文章abstract::A direct relationship between the weights of the brain and hemisphere and parameters characterizing the development of the cortex and its neurons in intact newborn rats was revealed. Parameters of brain development in newborn rats correlate with 3beta-hydroxysteroid dehydrogenase activity in the adrenal zona glomerulo...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-006-0070-y
更新日期:2005-12-01 00:00:00
abstract::In patients with ovarian cancer, the colony-forming capacity and radiosensitivity of clonogenic tumor cells from the primary node and metastases (ascites) differed considerably. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1012362804949
更新日期:2001-06-01 00:00:00
abstract::We studied regulation of hypoxanthine transport depending on its concentration in the culture medium. Caco-2 cells were differentiated on membrane filters to create a model of the intestine. Different hypoxanthine uptake on the apical and basolateral cell membranes was observed. The expression of SLC29 family genes en...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-015-3118-z
更新日期:2015-11-01 00:00:00
abstract::Pharmacokinetics of GVS-111, a new acylprolyldipeptide with nootropic properties and its penetration across the blood-brain barrier were studied in rats using HPLC. It was found that the dipeptide is absorbed in the gastrointestinal tract, enters the circulation, and penetrates through the blood-brain barrier in an un...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/BF02439270
更新日期:2000-04-01 00:00:00
abstract::The study examined the effect of endogenous lipid-soluble antioxidant coenzyme Q10 on the expression of UbiA gene of prenyltransferase domain-containing protein 1 (UbiAd1) involved in synthesis of vitamin K2 (and probably of coenzyme Q10) on a rat model of ischemic stroke provoked by ligation of the middle cerebral ar...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-018-4101-2
更新日期:2018-05-01 00:00:00
abstract::We performed a complex morphological analysis of atherosclerotic plaques obtained from 68 men with coronary atherosclerosis during coronary bypass surgery with endarterectomy. The expression of MMP-2 and MMP-9, collagen IV, CD31, CD34, factor VIII, and of smooth muscle cell actin was measured in the samples by morphom...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-018-4268-6
更新日期:2018-10-01 00:00:00
abstract::Changes in the diurnal light cycle affect the morphofunctional state of the pineal gland. The volume of the nucleus, Golgi apparatus, and mitochondria in pinealocytes decreases after 45-day exposure to bright light. After 90 days, the degree of nuclear polymorphism increased, the specific volume of the Golgi apparatus...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-010-1076-z
更新日期:2010-12-01 00:00:00
abstract::Comparative analysis of the state of the thymus, activity of cell component of the immune system, and open field behavior of Wistar and OXYS rats showed early involution of the thymus in OXYS rats. By morphological picture this involution corresponded to accidental involution and was paralleled by low level of delayed...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000020212.10768.9a
更新日期:2003-12-01 00:00:00
abstract::Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP-syndrome. Different disturbances of ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1015563225510
更新日期:2002-02-01 00:00:00
abstract::Local application of ointment with Bacillus spp. strain MG8 (15,000-20,000 living bacterial cells), isolated from permafrost specimens, on the skin wound of about 60 mm(2) stimulated the reparation processes in experimental mice. A possible mechanism stimulating the regeneration of the damaged tissues under the effect...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-015-2789-9
更新日期:2015-02-01 00:00:00
abstract::Prostatotropic activity of (3,5-dimethyl-4-hydroxy)benzyl thiododecane (T-DD) was evaluated on a model of benign prostatic hyperplasia induced in Wistar rats by chronic (2 months) intraperitoneal administration of sulpiride (40 mg/kg). Morphometric analysis of the dorsolateral lobe of the prostate showed that after th...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-019-04628-4
更新日期:2019-10-01 00:00:00
abstract::Local inflammatory response in the lungs and fi brogenic potential of multi-walled carbon nanotubes were studied in an acute aspiration experiment in mice. The doses were chosen based on the concentration of nanotubes in the air at a workplace of the company-producer. ELISA, fl ow cytometry, enhanced darkfield microsc...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-015-2835-7
更新日期:2015-03-01 00:00:00
abstract::Newborn rats received intraperitoneal injections of endothelin-1 in a daily dose of 5 x 10(-8)mol/kg 30 min after administration of NG-nitro-L-arginine methyl ester (9.3 x 10(-5)mol/kg intraperitoneally) from the 2nd to 6th day of life. NADPH diaphorase activity in epithelial and smooth muscle cells of the tracheobron...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1015826415361
更新日期:2002-03-01 00:00:00
abstract::Telocytes, a new type of interstitial stem cells with long thin processes that form a three-dimensional network around cardiomyocytes, vessels, and nerve fibers were described in the myocardium of children with tetralogy of Fallot. Two types of morphologically different telocytes, spindle-shaped and rounded, were iden...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04840-7
更新日期:2020-05-01 00:00:00
abstract::We studied the effect of turmeric extract in the composition of rectal suppositories on the level of LPO products and oxidative modification of proteins in the colon mucosa of Wistar rats with experimental Crohn's disease modeled by rectal administration of trinitrobenzenesulfonic acid. The suppositories containing tu...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04883-w
更新日期:2020-07-01 00:00:00
abstract::We studied the relationship between the length and tension in isolated strips of the capsules of bovine mesenteric lymph nodes. The deformation-strain and radius-pressure relationships were established in the lymph node. The capsule possesses high distensibility, modulus of elasticity at optimal tension was 0.09×10(5)...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1246-7
更新日期:2011-05-01 00:00:00
abstract::We studied the effect of histone deacetylase 1 (HDAC1) inhibition on titin content and expression of TTN gene in rat m. soleus after 3-day gravitational unloading. Male Wistar rats weighing 210±10 g were randomly divided into 3 groups: control, 3-day hindlimb suspension, and 3-day hindlimb suspension and injection of ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04907-5
更新日期:2020-08-01 00:00:00
abstract::The content of hemopoietic precursors in the bone marrow, its morphological composition, production of hemopoietic growth factors by cells of the hemopoietic microenvironment, erythropoietic activity, and plasma content of endogenous erythropoietin were studied in CBA/CaLac mice with hypoplasia of hemopoiesis induced ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1025469000276
更新日期:2003-06-01 00:00:00
abstract::We studied the role of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) in functional differentiation of HC11 mouse mammary gland cells. It was found that both IGF-1 and IGF-2 activate the expression of milk protein β-casein in the presence of prolactin and hydrocortisone. It was found that β-casein expression is...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1488-4
更新日期:2011-12-01 00:00:00
abstract::Patch-clamp and concentration jump studies showed that gadolinium ions dose-dependently reduced the amplitude of proton-activated currents (pH 6.5) in isolated Purkinje cells (gadolinium concentration producing a half-maximum effect was 69 microM for the peak and 8 microM for the stationary component of the current). ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-008-0077-7
更新日期:2008-03-01 00:00:00
abstract::We revealed an antimetastatic effect of thymus-dependent corpuscular antigen (sheep erythrocytes) injected intravenously or intraperitoneally in sensitizing or high doses alone or in a complex with a course dose of cyclophosphamide to C57Bl/6 mice with Lewis carcinoma. Injection of the antigen appreciably reduced the ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000042717.00428.e9
更新日期:2004-06-01 00:00:00
abstract::Immunophenotype of human bone marrow mesenchymal stem cells was studied after several culturing passages and after cryopreservation. Immunocytochemical analysis showed that bone marrow mesenchymal stem cells acquired homogeneity during in vitro culturing, but initially contained heterogeneous populations. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-006-0108-1
更新日期:2006-01-01 00:00:00
abstract::We compared cytotoxic activity of blood mononuclear leukocytes from healthy donors and lymphokine-activated killer cells generated from them towards tumor and normal cells. Lymphokine-activated killer cells exhibited higher (in comparison with blood mononuclear leukocytes) killer activity towards tumor cells. Lymphoki...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-007-0033-y
更新日期:2007-01-01 00:00:00
abstract::A new chromatographic procedure is proposed for rapid (35 min) complete fractionation of flavonoids in plant raw material; the method well discriminates between components with antioxidant activity (rutin, apigenin, quercetin, hesperidin). The method is based on reverse-phase high performance liquid chromatography usi...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-006-0273-2
更新日期:2006-06-01 00:00:00
abstract::We studied the effect of continuous vibration and treatment with licorice root (Glycyrrhiza glabra L.) on peripheral blood red cells in rabbits. Active substances of licorice root accelerated metabolism in cells of the bone marrow erythroid stem, enhanced compensatory reserve of the organism, and increased animal's re...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0444-6
更新日期:2005-08-01 00:00:00
abstract::Oxidative modification of fibrinogen in acute myocardial infarction increased 1.3-fold compared to that in CHD and 1.5-fold surpassed that in the control without CHD. Elevated content of oxidized fibrinogen correlated with increased levels of LPO products, von Willebrand factor, and fibrin degradation products, with a...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-008-0104-8
更新日期:2008-04-01 00:00:00
abstract::Here we review the mechanisms underlying systemic regulation of the genome in brain nerve cells. Expression of early and late behavioral genes is regulated by systemic processes in dominant functional systems. The main elements of this molecular and genetic cascade are similar during learning and development. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章,评审
doi:10.1023/a:1023843125404
更新日期:2003-02-01 00:00:00
abstract::The effects of cerivastatin on antiatherogenic properties of high-density lipoproteins were studied in patients with coronary heart disease and hyperlipidemia. Apart from hypolipidemic effects, cerivastatin changed the phospholipid composition of high-density lipoproteins and improved their cholesterol-acceptor proper...
journal_title:Bulletin of experimental biology and medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2000-10-01 00:00:00
abstract::Behavioral responses of 90-day-old male offspring from female Wistar rats exposed to restraint stress during the last week of pregnancy were studied in the formalin test. Specific biphasic behavioral response characterized acute (phase 1) and persistent tonic pain (phase 2). The intensity of nociceptive responses (eva...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1015530318241
更新日期:2002-02-01 00:00:00
abstract::Intranigral administration of glutamate to rats with parkinsonian syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine augmented the development of parkinsonian symptoms (oligokinesia and muscular rigidity), but did not affect motor activity of intact animals. Memantine administered intraperitoneally in pa...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/BF02682089
更新日期:2000-07-01 00:00:00