Blood lymphocyte proliferation reaction in autoimmune thyropathies.

Abstract:

:Spontaneous and stimulated reaction of lymphocyte proliferation and blood levels of CD25- and CD120-expressing lymphocytes were studied in patients with autoimmune thyroiditis and diffuse toxic goiter. Activation of CD25- and CD120-presenting function of blood lymphocytes was revealed. The findings indicate that the course of autoimmune thyroiditis and diffuse toxic goiter is associated with increased levels of basal, mitogen- and cytokine-stimulated proliferation of blood lymphocytes, particularly pronounced in thyroiditis in the euthyrosis stage.

journal_name

Bull Exp Biol Med

authors

Urazova OI,Kravets EB,Nedosekova YV,Rogaleva AV,Kuznecova VN,Rumpel OA

doi

10.1007/s10517-008-0278-0

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

286-8

issue

3

eissn

0007-4888

issn

1573-8221

pii

doi

journal_volume

146

pub_type

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