Effects of permafrost microorganisms on skin wound reparation.

Abstract:

:Local application of ointment with Bacillus spp. strain MG8 (15,000-20,000 living bacterial cells), isolated from permafrost specimens, on the skin wound of about 60 mm(2) stimulated the reparation processes in experimental mice. A possible mechanism stimulating the regeneration of the damaged tissues under the effect of MG8 could be modulation of the immune system reactivity with more rapid switchover to humoral immunity anti-inflammatory mechanisms aimed at de novo synthesis of protein.

journal_name

Bull Exp Biol Med

authors

Kalenova LF,Novikova MA,Subbotin AM

doi

10.1007/s10517-015-2789-9

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

478-82

issue

4

eissn

0007-4888

issn

1573-8221

journal_volume

158

pub_type

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