Abstract:
:Metabolic processes in the brain cortex of albino rats with prenatal and postnatal alcohol intoxication were studied by the method of electron paramagnetic resonance. Accumulation of superoxide radical-generating agents, inactivation of superoxide dismutase, and increase in nitric oxide concentration were detected. Activation of free radical processes was associated with accumulation of Mn(2+)and Fe(2+). The parameters of electron paramagnetic resonance returned to normal after Dolivin treatment. These changes were accompanied by a decrease in the intensity of oxidative metabolism.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Museridze DP,Sanikidze TV,Svanidze IKdoi
10.1007/s10517-006-0347-1subject
Has Abstractpub_date
2006-09-01 00:00:00pages
283-5issue
3eissn
0007-4888issn
1573-8221pii
doijournal_volume
142pub_type
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