Activity of angiotensin-converting enzyme in hereditary stress-induced arterial hypertension.

Abstract:

:We measured activity of angiotensin-converting enzyme in plasma and tissue of NISAG and normotensive WAG rats. In different organs of NISAG rats, activity of this enzyme did not differ from the corresponding values of WAG rats, although enzyme activity in the plasma of NISAG rats was significantly lower than that of WAG rats. Since NISAG rats are characterized by low activity of renin in the renal cortex, it is hypothesized that NISAG rats simulate the low-renin hypertension, in which inhibition of activity of the angiotensin-production system results from elevation of arterial pressure of central origin.

journal_name

Bull Exp Biol Med

authors

Cherkasova OP,Fedorov VI,Markel AL

doi

10.1007/s10517-005-0498-5

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

388-90

issue

4

eissn

0007-4888

issn

1573-8221

journal_volume

140

pub_type

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