Peculiarities of autonomic regulation assessed by variability of hemodynamic parameters in rats with different stress resistance.

abstract：:Hypoxia-induced immediate expression of transcription factor HIF-1α in the brain cortex is regulated by succinate produced in both the tricarbonic acid cycle and GABA shunt reactions and is induced by succinate-containing drugs. These facts prove the existence of succinate-dependent signalling regulation involved in i...

journal_title：Bulletin of experimental biology and medicine

authors： Lukyanova LD,Kirova YI,Germanova EL

更新日期：2018-01-01 00:00:00

abstract：:The effect of a 40-day toluene inhalation on learning of young and adult rats was examined in a multi-branched maze. Experimental rats of both age groups needed more time to pass the maze and made more errors than controls. This impairment was observed in young rats immediately after termination of toluene inhalation ...

journal_title：Bulletin of experimental biology and medicine

authors： Bikashvili TZ,Chilachava LR,Gelazonia LK,Japaridze NJ,Zhvania MG,Lordkipanidze TG,Okuneva VG

更新日期：2012-03-01 00:00:00

abstract：:We studied biocompatibility and bioresorption of 3D-printed polylactide and polyglycolide tissue membranes. Ultrasound microscopy and histological examination showed that membranes fabricated of a copolymer of lactic and glycolic acids in a mass ratio of 1:9 are bioresorbed and have good biocompatibility with soft tis...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EV,Petronyuk YS,Guseynov NA,Tereshchuk SV,Popov AA,Volkov AV,Gorshenev VN,Olkhov AA,Levin VM,Dymnikov AB,Rodionov VE,Tumanyan GA,Ivashkevich SG,Bonartsev AP,Borozdkin LL

更新日期：2021-01-01 00:00:00

abstract：:Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP-syndrome. Different disturbances of ...

journal_title：Bulletin of experimental biology and medicine

authors： Tereshchenko LV,Yudin AG,Kuznetsov Y,Latanov AV,Shul'govskii VV

更新日期：2002-02-01 00:00:00

abstract：:We studied the effects of various natural preparations, including extracts of Siberian ginseng, Rhodiola rosea, bergenia, and ginseng and pantohematogen on erythropoiesis under conditions of conflict situation. The test preparations were divided into 2 groups depending on their modulatory effect on intensified erythro...

journal_title：Bulletin of experimental biology and medicine

authors： Provalova NV,Skurikhin EG,Pershina OV,Minakova MY,Suslov NI,Dygai AM

更新日期：2003-08-01 00:00:00

abstract：:Using rat model of experimental sarcoma M-1 we studied the efficacy of photodynamic therapy with boronated chlorine as a photosensitizer in doses of 1.25, 2.5, 5.0, and 10.0 mg/ kg body weight. Laser irradiation was performed at energy densities of 150, 300 J/cm(2) and power density of 0.25 and 0.42 W/cm(2). Treatment...

journal_title：Bulletin of experimental biology and medicine

authors： Kaplan MA,Ol'shevskaya VA,Osipchuk YS,Nikitina RG,Kalinin VN

更新日期：2014-05-01 00:00:00

abstract：:Activities of antioxidant enzymes, vitamin E level, lactate dehydrogenase isoenzyme spectrum, and effects of melatonin on these parameters were studied in the myocardium of rats aged 6, 12, 18, and 24 months exposed to different illumination regimens. The greatest number of changes was recorded in rats exposed to perm...

journal_title：Bulletin of experimental biology and medicine

authors： Khizhkin EA,Ilukha VA,Ilyina TN,Unzhakov AR,Vinogradova IA,Anisimov VN

更新日期：2010-09-01 00:00:00

abstract：:We studied the correlation between the rank and age of baboons (n=12) with their cognitive abilities. A positive correlation was found between performances of different tests by male. The ability to solve the tests related to bait placement depended on the age of the males and age-related hierarchical status. Four-yea...

journal_title：Bulletin of experimental biology and medicine

authors： Anikaev AE,Chalyan VG,Meishvili NV

更新日期：2018-08-01 00:00:00

abstract：:Treadmill training of spinalized rats creates conditions for early appearance of rhythmic locomotor movements of the hind limbs. Recovery of the movements was paralleled by an appropriate structural organization of neurons in the anterior horns of the distal compartment of the spinal cord. ...

journal_title：Bulletin of experimental biology and medicine

authors： Moshonkina TR,Gilerovich EG,Fedorova EA,Avelev VD,Gerasimenko YP,Otellin VA

更新日期：2004-08-01 00:00:00

abstract：:We developed a method for collection and processing of scintigraphic data to estimate myocardial reserve in a gamma-chamber with cadmium-zinc-telluride detectors. Dynamic single-photon emission computed tomography of the heart with (99m)Tc-Technetril was performed in 16 coronary heart disease patients at rest and duri...

journal_title：Bulletin of experimental biology and medicine

authors： Mochula AV,Zavadovsky KV,Lishmanov YB

更新日期：2016-04-01 00:00:00

abstract：:Systemic administration of ACTH to rats with normal hormone production induced a rapid (started 3 min postinjection) and long-term (persisted 30 min) elevation of pain threshold. Complete inhibition of glucocorticoid production shortened the duration of ACTH-induced analgesia to 15 min. The biphasic effect of ACTH on ...

journal_title：Bulletin of experimental biology and medicine

authors： Bogdanov AI,Yarushkina NI

更新日期：2001-03-01 00:00:00

abstract：:The paper presents the basic criteria for glycemic control in type 2 diabetes mellitus, the data on the relationship between postprandial glycemia and the development of the late vascular complications, and methods for evaluating the glycemic index of foodstuffs and dishes in order to optimize the diets and improve th...

journal_title：Bulletin of experimental biology and medicine

authors： Sharafetdinov KhKh,Lapik IA,Vorozhko IV,Tutelyan VA

更新日期：2015-05-01 00:00:00

abstract：:Glutathione S-transferase activity increased in rats with acute pancreatitis: 2.2 times on day 2, 2-fold on day 4, and 1.5 times on day 10. Inducers of microsomal enzymes aroclor 1254 and phenobarbital notably inhibited glutathione S-transferase activity in animals with experimental pancreatitis on days 2-4 of the dis...

journal_title：Bulletin of experimental biology and medicine

authors： Prokop'eva NV,Gulyaeva LF

更新日期：2000-05-01 00:00:00

abstract：:Comparative analysis of the efficiency of PCR and microbiological methods for deciphering of the etiological structure of non-nosocomial pneumonias demonstrated the diagnostic significance of detecting Streptococcus pneumoniae DNA in the blood, but not sputum. Mechanisms of penetration of S. pneumoniae into the blood ...

journal_title：Bulletin of experimental biology and medicine

authors： Artemova LV,Beskhlebnaya VA,Ezhova LG,Kirillov MY,Kravtsov EG,Dalin MV

更新日期：2003-10-01 00:00:00

abstract：:The content of catecholamines and their metabolites in the brain and the relationship between cerebral catecholamine levels and their urinary excretion were studied in rats with 6-OHDA-induced hemiparkinsonism. 6-OHDA reduced brain concentrations of dopamine, DOPAC, and homovanilic acid and urinary excretion of dopami...

journal_title：Bulletin of experimental biology and medicine

authors： Chekhonin VP,Baklaushev VP,Kogan BM,Savchenko EA,Lebedev SV,Man'kovskaya IV,Filatova TS,Yusupova IU,Dmitrieva TB

更新日期：2000-08-01 00:00:00

abstract：:We performed a comparative study of the cytotoxicity of cisplatin, JM216 complex, and aminonitroxyl platinum(IV) complexes for HeLa cells grown in monolayer and 3D culture. The growth dynamics of spheroids was studied and optimal conditions for evaluation of cytotoxicity were determined. Spheroids were less sensitive ...

journal_title：Bulletin of experimental biology and medicine

authors： Trigub ММ,Filatova NV,Areshidze DА,Sen' VD,Terentiev АА

更新日期：2020-02-01 00:00:00

abstract：:Study on a model of 6-day dosed adaptation to heat in rats showed that this adaptation decreased the severity of cardiac arrhythmias during ischemic and reperfusion injury. The duration of arrhythmias decreased not only in the ischemic period, but also under conditions of reperfusion. Adaptation delayed the developmen...

journal_title：Bulletin of experimental biology and medicine

authors： Monastyrskaya EA,Belkina LM,Manukhina EB,Malyshev IY

更新日期：2007-01-01 00:00:00

abstract：:We studied the specific features of ultrasonic vocalization of Wistar rats in various motivational and emotional states. No significant changes were found in ultrasonic vocalization of rats during experimental food motivation and after the satisfaction of food requirements. The state of thirst and satisfaction of wate...

journal_title：Bulletin of experimental biology and medicine

authors： Pertsov SS,Koplik EV,Karkishchenko NN,Sudakov KV

更新日期：2012-10-01 00:00:00

abstract：:Activation of lysosomal proteolysis and increased coenzyme Q10 level were revealed in the liver and brain of rats with individual typological features under conditions of food deprivation. Changes in cathepsin B activity in these tissues were different in behaviorally active and passive animals. We observed indirect m...

journal_title：Bulletin of experimental biology and medicine

authors： Kirbaeva NV,Sharanova NE,Zhminchenko VM,Vasil'ev AV

更新日期：2018-07-01 00:00:00

abstract：:Reductase activity of 17beta-hydroxysteroid oxidoreductase in biopsy specimens of prostatic cancer and benign hyperplasia, and prostatic intraepithelial neoplasia and serum concentrations of testosterone, 5alpha-dihydrotestosterone, 4-androstene-3,17-dione were compared in patients and healthy individuals. Reductase a...

journal_title：Bulletin of experimental biology and medicine

authors： Degtyar VG,Babkina TV,Kazantseva IA,Morozov AP,Trapeznikova MF,Kushlinskii NE

更新日期：2005-06-01 00:00:00

abstract：:Intravenous infection of chicken with H5N1 avian influenza virus (strain A/Gs/Krasnoozerskoye/627/05) causes rapid lethal outcome. Pathomorphological study of bird viscera showed manifestations of disseminated intravascular coagulation syndrome, generalized inflammatory reaction, and wide-scale necrobiotic changes in ...

journal_title：Bulletin of experimental biology and medicine

authors： Shestopalova LV,Shkurupiy VA,Sharkova TV,Shestopalov AM

更新日期：2008-12-01 00:00:00

abstract：:We studied the effect of anti-inflammatory cytokine IL-4 (5 μg/kg intraperitoneally) on peripheral blood leukocytes in Wistar rats with various behavioral characteristics during acute emotional stress (1-h immobilization with simultaneous subthreshold electrocutaneous stimulation). IL-4 reduced the differences in bloo...

journal_title：Bulletin of experimental biology and medicine

authors： Pertsov SS,Koplik EV,Kalinichenko LS

更新日期：2015-03-01 00:00:00

abstract：:The parameters of thermal dependence of H+ transport into human erythrocytes in the presence of furosemide were measured. The relationship between these changes and function of band 3 protein of the erythrocyte membrane is discussed. ...

journal_title：Bulletin of experimental biology and medicine

authors： Mishchenko AA,Irzhak LI

更新日期：2004-07-01 00:00:00

abstract：:Lyzed epimastigotes of Trypanosoma cruzi clones P209-1, Gamba1, Sp104-1, MASu, Y7/1, MN12, Cl-Brener, 86/2036, Y7/2-1 inhibit the growth of Ehrlich adenocarcinoma in mice. the tumor decreased 1.5-3 times after 12 daily injections of lysates from 15 million epimastigotes. The protective effect progressed after the inje...

journal_title：Bulletin of experimental biology and medicine

authors： Batmonkh Z,Kallinikova VD,Pakhorukova LV,Kravtsov EG,Karpenko LP,Dalin MV

更新日期：2006-10-01 00:00:00

abstract：:We studied properties of bacterial biofilms during long-term culturing. The biofilms were preserved for more than 90 days under the chosen conditions. At the same time, amounts of matrix and cells underwent periodic changes. The biomass of the biofilms decreased approximately every 7 days and then returned to the prev...

journal_title：Bulletin of experimental biology and medicine

authors： Tetz GV,Artemenko NK,Zaslavskaya NV,Tetz VV

更新日期：2013-08-01 00:00:00

abstract：:Formation of Ala-Glu-Asp-Gly peptide complex with duplex DNA [poly(dA-dT):poly(dA-dT)] at neutral pH and ambient temperature was studied experimentally. Peptide binding to duplex DNA was associated with hyperchromic effect indicating local separation of the double helix. Energies of paired interactions between amino a...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Solovyov AY,Shataeva LK

更新日期：2006-04-01 00:00:00

abstract：:Experiments on hepatocyte culture showed that apolipoprotein A-I-tetrahydrocortisol complex increases the rate of DNA, RNA, and protein biosynthesis measured by radioactive label incorporation. Apolipoprotein E acted as competitor of the apolipoprotein A-I-tetrahydrocortisol complex and abolished biological activity o...

journal_title：Bulletin of experimental biology and medicine

authors： Panin LE,Sumenkova DV,Knyazev RA,Polyakov LM

更新日期：2007-12-01 00:00:00

abstract：:We studied the effects of dopamine D1/D2 receptor antagonists on the dynamics of acquisition and extinction of active avoidance responses and open field behavior in ovariectomized female rats. Dopamine D1 receptor antagonist SCH-23390 (0.1 mg/kg intraperitoneally) and dopamine D2 receptor antagonist sulpiride (10.0 mg...

journal_title：Bulletin of experimental biology and medicine

authors： Fedotova YO,Sapronov NS

更新日期：2014-03-01 00:00:00

abstract：:The peculiarities of the histological structure and morphometrical parameters of the dentition in ISIAH rats (inherited stress-induced arterial hypertension) before stress and after modeling of everyday life stress regimen (chronic stress) were compared with those in WAG rats. The area of blood vessels of the periodon...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LR,Darenskaya MA,Kolesnikova LI,Grebenkina LA,Korytov LI,Batoroev YK,Belinskaya EI,Mikhalevich IM,Kolesnikov SI

更新日期：2019-05-01 00:00:00

abstract：:We studied the effects of phenazepam (0.075 mg/kg) after pretreatment (5 minutes before) with naloxone (10 mg/kg) on open-field behavior of C57Bl/6 and BALB/c mice. In ex vivo experiments, we studied the effects of naloxone (1 and 10 mg/kg) on receptor binding of [(3)H]-flunitrazepam by membranes of brain fraction (P1...

journal_title：Bulletin of experimental biology and medicine

authors： Seredenin SB,Nadorova AV,Kolik LG,Yarkova MA

更新日期：2013-07-01 00:00:00