Correction of furosemide-induced magnesium deficiency with different stereoisomers of organic magnesium salts: a comparative study.

Abstract:

:We compared the efficiency of different stereoisomers of organic magnesium salts (Mg DL-, Mg D-, and Mg L-aspartate and Mg L- and Mg DL-glutamate) after oral administration under conditions of furosemide-induced magnesium deficiency. The time to complete compensation of erythrocyte magnesium level was 5 days for Mg L-aspartate, 10 and 8 days for Mg L-glutamate and Mg D-aspartate, respectively, and 11 days for Mg DL-aspartate and Mg DL-glutamate. These findings attest to better bioavailability of Mg complex with L-stereoisomer of aspartate in comparison with DL and D-stereoisomers and stereoisomers of Mg glutamate.

journal_name

Bull Exp Biol Med

authors

Spasov AA,Ozerov AA,Iezhitsa IN,Kharitonova MV,Kravchenko MS,Zheltova AA

doi

10.1007/s10517-011-1323-y

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

333-5

issue

3

eissn

0007-4888

issn

1573-8221

journal_volume

151

pub_type

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