Morphofunctional characteristics of fetoplacental barrier of placental villi during pregnancy complicated by herpes-virus infection.

abstract：:Characteristics of distribution of cholinergic and adrenoceptor structures along the sinoatrial node artery in rat heart were evaluated by autoradiography on semithin sections by determining the density of (3)H-dihydroalprenolol and (3)H-quinuclidinyl benzilate binding sites. The relative density of binding sites for ...

journal_title：Bulletin of experimental biology and medicine

authors： Sutyagin PV,Kalinina EE,Pylaev AS

更新日期：2005-07-01 00:00:00

abstract：:The study was undertaken to determine the mechanism of carnosine effect on cell proliferation. We studied the effect of carnosine and its derivatives on cell cycle progression in cultured rat pheochromocytoma cells (PC-12). It was found that 48-h incubation of PC-12 cells with carnosine in concentrations of 10-50 mM l...

journal_title：Bulletin of experimental biology and medicine

authors： Rybakova YS,Boldyrev AA

更新日期：2012-11-01 00:00:00

abstract：:We studied the effect of audiovisual stimulation training course on physical development, functional state of the cardiovascular system, blood biochemical parameters, and hormonal status of athletes. The training course led to improvement of physical performance and adaptive capacities of the circulatory system, incre...

journal_title：Bulletin of experimental biology and medicine

authors： Golovin MS,Golovin MS,Aizman RI

更新日期：2016-09-01 00:00:00

abstract：:Here we addressed a question of whether gamma oscillations previously described in the whisker-related barrel cortex are a universal pattern of activity in the somatosensory cortex of newborn rats. Intracortical recording of local field potentials and action potentials in neurons using multisite silicon electrodes in ...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimova EV,Zakharov AV,Lebedeva YA,Inacio AR,Minlebaev MG,Sitdikova GF,Khazipov RN

更新日期：2014-01-01 00:00:00

abstract：:Anaferon (pediatric formulation) administered in the therapeutic-and-prophylactic regimen to mice receiving intranasally 100% infecting dose of A/California/07/2009(H1N1)v influenza virus exhibited an antiviral effect and 10-fold reduced the production of influenza virus in the lungs of infected mice on days 4, 6, and...

journal_title：Bulletin of experimental biology and medicine

authors： Shishkina LN,Skarnovich MO,Kabanov AS,Sergeev AA,Olkin SE,Tarasov SA,Belopolskaya MV,Sergeeva SA,Epstein OI,Malkova EM,Stavsky EA,Drozdov IG

更新日期：2010-10-01 00:00:00

abstract：:Castration had no effect on baseline BP and vascular sensitivity to acetylcholine and deficiency of nitric oxide and prostacyclin in normotensive specimens. Castration of hypertensive specimens decreased BP and potentiated the hypotensive effects of acetylcholine, but did not modulate vascular sensitivity to the block...

journal_title：Bulletin of experimental biology and medicine

authors： Semyachkina-Glushkovskaya OV,Anishchenko TG,Kuznetsova AS,Kuznetsova YV,Bibikova OA,Sjestnova AA

更新日期：2012-06-01 00:00:00

abstract：:We studied the role of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) in functional differentiation of HC11 mouse mammary gland cells. It was found that both IGF-1 and IGF-2 activate the expression of milk protein β-casein in the presence of prolactin and hydrocortisone. It was found that β-casein expression is...

journal_title：Bulletin of experimental biology and medicine

authors： Shushanov SS

更新日期：2011-12-01 00:00:00

abstract：:MEK, PI3, p38, tyrosine, and mTOR kinases are not involved in the regulation of heart resistance to the arrhythmogenic action of short-term ischemia/reperfusion in non-adapted rats. ...

journal_title：Bulletin of experimental biology and medicine

authors： Maslov LN,Mukhomedzyanov AV,Tsibulnikov SY,Chauski EI,Khaliulin IG,Portnichenko AG

更新日期：2015-04-01 00:00:00

abstract：:Digital simulation of disorders in the p53 and Mdm2 protein system, involved in repair of DNA defects and in many vital processes, including tumor formation, neurodegeneration, and aging, was carried out on the base of functional nonlinear octoparametric mathematical model. Stress situations were studied, associated w...

journal_title：Bulletin of experimental biology and medicine

authors： Voropaeva OF,Shokin YI,Nepomnyashchikh LM,Senchukova SR

更新日期：2014-08-01 00:00:00

abstract：:A combination of electrochemical lysis and photodynamic therapy were used to attain complete resorption of M-1 sarcoma in rats; both treatment modalities were used with minimum parameters. Fotolon served as the photosensitizer for photodynamic therapy. Accumulation of the sensitizer in the tumor and normal tissue was ...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhailovskaya AA,Kaplan MA,Brodskij RA,Bandurko LN

更新日期：2009-01-01 00:00:00

abstract：:Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively. Thus, the previously reported cardioprotective activity of this tetrapeptide is determined by i...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Lin'kova NS,Polyakova VO,Kvetnoy IM,Benberin VV,D'yakonov MM,Titkov YS

更新日期：2012-08-01 00:00:00

abstract：:Cardiac and plasma activities of marker lysosomal enzymes were studied in Wistar rats with metabolic (epinephrine) and occlusion (ligation of coronary arteries) myocardial infarction. Activity of all examined lysosomal enzymes significantly increased in the myocardium and blood plasma starting from the first day after...

journal_title：Bulletin of experimental biology and medicine

authors： Mayanskaya SD,Mayanskaya NN,Efremov AV,Yakobson GS

更新日期：2000-06-01 00:00:00

abstract：:Addition of anaferon (pediatric formulation) to the therapy of chickenpox patients led to more rapid disappearance of the main symptoms and alleviated the course of the disease. The safety of the preparation is confirmed by the absence of undesirable events and stability of laboratory indexes against the background of...

journal_title：Bulletin of experimental biology and medicine

authors： Timchenko VN,Pavlova EB,Chernova TM,Bannova SL,Savel'eva TI,Tarasov SA,Kachanova MV,Siver'yanova MA

更新日期：2009-08-01 00:00:00

abstract：:The study examined the effect of endogenous lipid-soluble antioxidant coenzyme Q10 on the expression of UbiA gene of prenyltransferase domain-containing protein 1 (UbiAd1) involved in synthesis of vitamin K2 (and probably of coenzyme Q10) on a rat model of ischemic stroke provoked by ligation of the middle cerebral ar...

journal_title：Bulletin of experimental biology and medicine

authors： Povarova OV,Balatsky AV,Gusakov VS,Medvedev OS

更新日期：2018-05-01 00:00:00

abstract：:The effect of a 40-day toluene inhalation on learning of young and adult rats was examined in a multi-branched maze. Experimental rats of both age groups needed more time to pass the maze and made more errors than controls. This impairment was observed in young rats immediately after termination of toluene inhalation ...

journal_title：Bulletin of experimental biology and medicine

authors： Bikashvili TZ,Chilachava LR,Gelazonia LK,Japaridze NJ,Zhvania MG,Lordkipanidze TG,Okuneva VG

更新日期：2012-03-01 00:00:00

abstract：:The relationships between open field behavior, initial nociceptive thresholds, and immunoreactivity assessed according to the development of hyperthermia triggered by LPS pyrogenal were examined in Wistar rats. Behaviorally active animals demonstrated higher nociceptive thresholds and greater immunoreactivity in compa...

journal_title：Bulletin of experimental biology and medicine

authors： Abramova AY,Abramov YB

更新日期：2011-12-01 00:00:00

abstract：:The degree of oxygen consumption in rats was determined after intraperitoneal injection of morphine in a single dose of 5 mg/kg. Some animals were injected with morphine and perorally received morphine or antibodies to mu-opiate receptors in ultralow doses obtained by the technology of potentiation. Potentiated substa...

journal_title：Bulletin of experimental biology and medicine

authors： Pavlov IF,Epstein OI

更新日期：2003-01-01 00:00:00

abstract：:Groups of microRNA genes, methylation of which is associated with the initial (I-II) stages of breast cancer, are determined, and new markers and marker systems for the disease diagnosis were created on the basis of these data. A total of 14 genes in which methylation was associated with breast cancer were identified ...

journal_title：Bulletin of experimental biology and medicine

authors： Braga EA,Filippova EA,Loginov VI,Pronina IV,Burdennyi AM,Kazubskaya TP,Fridman MV,Khodyrev DS,Kushlinskii NE

更新日期：2019-12-01 00:00:00

abstract：:We studied anticonvulsant effects of combined treatment with citicoline, a nootropic substance with neuroregenerative and neuroprotective activities, and valproate, an antiepileptic agent widely used in the treatment of epilepsy, on the model of pentylenetetrazole-induced (75 mg/kg, intraperitoneally) acute generalize...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova MN,Kuznetsova LV,Zin'kovskii KA,Klishina NV

更新日期：2016-02-01 00:00:00

abstract：:Transcription profiles of genes of local immune response were determined in the vagina of women with bacterial vaginosis, aerobic vaginitis, and vulvovaginal candidosis for detection of the most specific immune markers for these vaginal infections. Laboratory diagnosis of the vaginal infections was performed microscop...

journal_title：Bulletin of experimental biology and medicine

authors： Budilovskaya OV,Shipitsina EV,Spasibova EV,Pereverzeva NA,Vorob'eva NE,Tsypurdeeva ND,Grigoryev AN,Savicheva AM

更新日期：2020-03-01 00:00:00

abstract：:The development of MPTP-induced depressive syndrome in rats was accompanied by activation of prolyl endopeptidase and dipeptidyl peptidase IV in the brain frontal cortex. Prolyl endopeptidase activity in the striatum also increased under these conditions. Our results indicate that proline-specific peptidases in the ta...

journal_title：Bulletin of experimental biology and medicine

authors： Krupina NA,Zolotov NN,Bogdanova NG,Orlova IN,Khlebnikova NN,Kryzhanovskii GN

更新日期：2006-11-01 00:00:00

abstract：:Peroral administration of alpha-tocopherol in a daily dose of 150 mg/kg for 1, 4, 8, and 12 days leads to induction of cytochromes P450 1A in male rats. Activity of CYP1A1 and CYP1A2 increased most significantly one day after alpha-tocopherol administration (by 2.6 and 2.7 times, respectively). CYP1A1 was immunohistoc...

journal_title：Bulletin of experimental biology and medicine

authors： Sidorova YA,Grishanova AY,Lyakhovich VV

更新日期：2004-09-01 00:00:00

abstract：:The mechanisms of therapeutic resistance of human glioblastoma multiforme are analyzed. The authors make an attempt at systematization and scientific theoretical validation of new approaches to creation of biomedical cellular preparations, based on the oncoproteomic technologies, for personified therapy of the glial t...

journal_title：Bulletin of experimental biology and medicine

authors： Bryukhovetskii IS,Bryukhovetskii AS,Khotimchenko YS

更新日期：2015-04-01 00:00:00

abstract：:Ultralow doses of antibodies to histamine in produced an antiproliferative effect on experimental animals with inflammation. Analgesic activity of antibodies to histamine was revealed on the model of acetic acid-induced writhing. ...

journal_title：Bulletin of experimental biology and medicine

authors： Krylova SG,Razina TG,Zueva EP,Amosova EN,Shilova NV,Dugina YL,Epstein OI

更新日期：2003-01-01 00:00:00

abstract：:We studied the effect of mesenchymal stromal cells and conditioned media on healing of full-thickness skin wound in rats. Cell transplantation to the wound bed did not accelerate wound closing and had no effect on the severity of inflammation, but increased vasculariza - tion of the granulation tissue in 14 days after...

journal_title：Bulletin of experimental biology and medicine

authors： Payushina OV,Butorina NN,Sheveleva ON,Domaratskaya EI

更新日期：2018-08-01 00:00:00

abstract：:Non-clonal and clonal abnormal cells (hypodiploid, polyploid, and with chromosome aberrations) were detected by the G-method in the bone marrow and blood of the majority of patients with non-Hodgkin lymphomas before therapy. The manifestation of these abnormalities changed individually after treatment. The most incide...

journal_title：Bulletin of experimental biology and medicine

authors： Ankina MA,Zavitaeva TA,Panferova TA,Shakhtarina SV,Pavlov VV

更新日期：2007-02-01 00:00:00

abstract：:Cell cultures isolated from human endometrium by enzyme digestion consisted of highly viable fibroblast-like mesenchymal cells expressing CD90, CD73, and CD105. During passage 1, the cultures contained a small fraction of cytokeratin-7(+) epithelial cells that disappeared by passage 2. The cultures from the endometriu...

journal_title：Bulletin of experimental biology and medicine

authors： Savilova AM,Yushina MN,Rudimova YV,Khil'kevich EG,Chuprynin VD

更新日期：2016-02-01 00:00:00

abstract：:We revealed a significant positive correlation between the concentrations of tissue VEGF and its receptor VEGFR2 in the primary tumor. The degree and direction of changes in the content of VEGF and VEGFR2 in cytosols of tumors from patients with locally spread breast cancer during the preoperation therapy depended on ...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EA,Gershtein ES,Vysotskaya IV,Kushlinskii NE

更新日期：2008-02-01 00:00:00

abstract：:Here we present the results of histochemical detection of 3β-hydroxysteroid dehydrogenase in neurons of the neocortex, cerebellum, and brainstem. The positive reaction was observed in a low number of neocortical, midbrain, and pontine neurons. The maximum number of positive neurons was detected in the cerebellar corte...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva VM

更新日期：2012-01-01 00:00:00

abstract：:For evaluation of the spatial structure of chromatin in nuclei of mesenchymal SC we determined the position of centromeres and individual chromosomes in interphase nucleus of mesenchymal SC. More than 300 nuclei in 7 cultures of mesenchymal SC were analyzed. Centromeres of chromosomes 6, 8, and 11 lie at a longer (0.6...

journal_title：Bulletin of experimental biology and medicine

authors： Lavrov AV,Voldgorn YI

更新日期：2011-08-01 00:00:00