Expression of surface lymphocyte markers in various courses of gastrointestinal tumors.

abstract：:We studied the effects and mechanisms of action of NaHS, an H2S donor, on isolated phenylephrine-precontracted bovine mesenteric lymph nodes. NaHS induced concentration-dependent relaxation of lymph nodes. Removal of the endothelium reduced, but did not abolish the relaxing effect of NaHS. The relaxing effect was redu...

journal_title：Bulletin of experimental biology and medicine

authors： Lobov GI

更新日期：2020-06-01 00:00:00

abstract：:We studied the effect of a biomedical cell product (bone marrow multipotent mesenchymal stromal cells and products secreted by these cells in conditioned medium) on subpopulation composition of lymphoid cells of central and peripheral lymphoid organs of Wistar rats under normal conditions. Changes in the subpopulation...

journal_title：Bulletin of experimental biology and medicine

authors： Konenknov VI,Borodin YI,Dergacheva TI,Shurlygina AV,Mel'nikova EV,Tenditnik MV,Starkova EV,Lykov AP,Poveshchenko OV,Bondarenko NA,Kim II

更新日期：2016-05-01 00:00:00

abstract：:Enlargement of the brain weight was attained in rats by reducing the number of neonates in the litter. The brain of 14- and 30-day-old animals was examined (controls: intact animals from litters of average numbers). Difference between the brain weight at 14 and 30 days was about 200 mg. The parameter in the experiment...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva EM

更新日期：2012-11-01 00:00:00

abstract：:Experiments on "stationary aging" cultures of B11dii-FAF28 Chinese hamster cells showed that contact inhibition of cell growth and further culturing of cells in the stationary phase led to continuous inhibition of enzymes realizing poly-ADP-ribosylation of chromatin proteins. Cell density in the monolayer and percenta...

journal_title：Bulletin of experimental biology and medicine

authors： Shram SI,Shilovskii GA,Khokhlov AN

更新日期：2006-05-01 00:00:00

abstract：:We studied the mechanisms of induction of recombinase activity in peripheral T cells of patients with autoimmune type 1 diabetes mellitus. It was shown that the presence of CD40 on T cell membrane (not typical of these cells) is crucial for this process: expression of recombinase RAG-1 in diabetic patients was detecte...

journal_title：Bulletin of experimental biology and medicine

authors： Kuklina EM,Gorbunova OL,Smirnova EN

更新日期：2012-01-01 00:00:00

abstract：:A series of short neurotoxins (molecular weight 3500-5000 D) was isolated from Vietnamese scorpion B. occitanus sp. All these toxins blocked generation of action potentials (this effect depended on their molecular weight), but did not change conduction velocity and excitation threshold of the nerve. ...

journal_title：Bulletin of experimental biology and medicine

authors： Hoang NA,Maksimov GV,Berezin BB,Piskarev VE,Yamskov IA

更新日期：2001-10-01 00:00:00

abstract：:Experimental study of a new paramagnetic complex Mn-DCTA is carried out. The complex (0.5 M manganese(II) solution with trans-1,2-diamine cyclohexane-N,N,N',N'-tetraacetic acid; Cyclomang) was used for contrast magnetic resonance imaging visualization of CNS involvement in dogs with severe forms of Babesia canis infec...

journal_title：Bulletin of experimental biology and medicine

authors： Ussov WY,Belyanin ML,Bezlepkin AI,Borodin OY,Bobrikova EE,Shimanovskii NL

更新日期：2016-09-01 00:00:00

abstract：:The appearance of autoantibodies to neuronal proteins (S100, GFAP, MBP, and NGF) in rat serum was analyzed by ELISA on days 5, 10, 17, 25, and 32 after streptozotocin injection. Simultaneously, blood glucose and insulin autoantibodies were assayed. Serum glucose level increased on the next day after streptozotocin inj...

journal_title：Bulletin of experimental biology and medicine

authors： Lotosh NG,Savel'eva EK,Selishcheva AA,Savel'ev SV

更新日期：2013-05-01 00:00:00

abstract：:We studied electrophysiological parameters and morphological changes in the adrenal glands and spleen of CBA mice feeding a low-choline diet and/or ethanol-containing diet. The polarization coefficient underwent similar changes in the adrenal glands and spleen, which was associated with different contribution of imped...

journal_title：Bulletin of experimental biology and medicine

authors： Tornuev YV,Nepomnyashchikh LM,Koldysheva EV

更新日期：2005-11-01 00:00:00

abstract：:Fragments of extracellular DNA are permanently released into the blood flow due to cell apoptosis and possible de novo DNA synthesis. To find out whether extracellular DNA can affect the synthesis of nitric oxide (NO), one of key vascular tone regulators, we studied in vitro effects of three artificial DNA probes with...

journal_title：Bulletin of experimental biology and medicine

authors： Efremova LV,Alekseeva AY,Konkova MS,Kostyuk SV,Ershova ES,Smirnova TD,Konorova IL,Veiko NN

更新日期：2010-08-01 00:00:00

abstract：:We studied erythropoiesis in newborn infants delivered by mothers with normal pregnancy and gestosis. The effects of placental extracts on hemopoiesis in JCR mice were also evaluated. Our results suggest that the placenta is involved in the regulation of fetal erythropoiesis. The placenta activates fetal erythropoiesi...

journal_title：Bulletin of experimental biology and medicine

authors： Evseenko DA,Tsirel'nikov NI

更新日期：2001-11-01 00:00:00

abstract：:We studied the effect of constant illumination for 1 month on female GC (genetic catalepsy) and Wistar rats (control). Light exposure decreased the degree of cataleptic freezing in female GC rats (compared to the control). Norepinephrine concentration in cataleptic rats returned to normal under these conditions: this ...

journal_title：Bulletin of experimental biology and medicine

authors： Klotchkov DV,Alekhina TA,Ukolova TN,Rjazanova MA

更新日期：2008-07-01 00:00:00

abstract：:Oxidative modification of fibrinogen in acute myocardial infarction increased 1.3-fold compared to that in CHD and 1.5-fold surpassed that in the control without CHD. Elevated content of oxidized fibrinogen correlated with increased levels of LPO products, von Willebrand factor, and fibrin degradation products, with a...

journal_title：Bulletin of experimental biology and medicine

authors： Ragino YI,Baum VA,Polonskaya YV,Sadovski EV,Baum SR,Nikitin YP

更新日期：2008-04-01 00:00:00

abstract：:The stimulatory effect of a local focus of granulation tissue, created in the bone marrow cavity, on reparative osteogenesis after tibial bone fracture was detected in experimental rats by microscopic examination of histological sections, scanning electron microscopy, and X-ray electron probe microanalysis. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ir'yanov YM,Dyuryagina OV

更新日期：2014-05-01 00:00:00

abstract：:We studied expression of Flt-1 and Flk-1 receptors on tumor cells obtained from 83 patients with locally advanced breast cancer after neoadjuvant chemotherapy. The mean period of observations was 32.3 months. The median recurrence-free survival periods for Flt-1(+) and Flt-1(-) patients were 55 and 32 months, respecti...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova LG,Zhukov NV,Lichinitser MR

更新日期：2003-05-01 00:00:00

abstract：:Integral activity of neutral deoxyribonucleases in the plasma and urine or donors, patients with benign prostatic hyperplasia, and patients with stomach and prostatic cancer was studied by IFA based on hydrolysis of DNA fragment modified with haptene molecules. In donors plasma deoxyribonuclease activity was 0.16+/-0....

journal_title：Bulletin of experimental biology and medicine

authors： Tamkovich SN,Cherepanova AV,Bryzgunova OE,Kolesnikova EV,Permyakova VI,Vlassov VV,Laktionov PP

更新日期：2008-07-01 00:00:00

abstract：:Using comet assay we studied the effect of anxiolytic afobazole, exhibiting also antioxidant and antimutagenic properties, on spontaneous and ex-vivo hydrogen peroxide-induced DNA damage in blood cells from patients with systemic lupus erythematosus. Afobazole treatment (30-60 mg/day for 1 month) in addition to standa...

journal_title：Bulletin of experimental biology and medicine

authors： Zhanataev AK,Lisitsyna TA,Durnev AD,Nasonov EL,Seredenin SB

更新日期：2009-10-01 00:00:00

abstract：:Electrophysiological parameters of true pacemakers in the sinoatrial node of rat heart were recorded intracellularly using glass microelectrodes. In 11 of 13 experiments acetylcholine in increasing doses did not induce migration of the dominant pacemaker region, while in two cases its minor migration upstream the sinu...

journal_title：Bulletin of experimental biology and medicine

authors： Sutyagin PV,Kalinina EE,Pylaev AS

更新日期：2004-08-01 00:00:00

abstract：:Autooxidation of low-density lipoproteins during incubation at 37 degrees C was accompanied by accumulation of LPO products, decrease in UV autofluorescence (FUV), and increase in autofluorescence in the visible band (FVIS). The degree of low-density lipoprotein modification was estimated by calculating the FVIS/FUV r...

journal_title：Bulletin of experimental biology and medicine

authors： Aidyraliev RK,Azizova OA,Vakhrusheva TV,Lopukhin YM,Mirrakhimov MM

更新日期：2006-10-01 00:00:00

abstract：:The intensity of calcium and phosphate accumulation in regenerating bone tissue decreased significantly during the posttraumatic period in 54 male CBA mice with acute hepatic intoxication. The formation of organic components of the bone decreased to a lesser degree. Creatine metabolism in the muscles of damaged segmen...

journal_title：Bulletin of experimental biology and medicine

authors： Stogov MV,Luniova SN,Tkachuk EA

更新日期：2010-10-01 00:00:00

abstract：:Antitumor efficiencies of cytostatics dioxadet, cisplatin, mitomycin C, melphalan, and paclitaxel after a single intraperitoneal or intravenous injection in doses of 1.5, 4, 1.5, 2, and 5 mg/kg, respectively, were studied on the model of transplanted ovarian tumor in 124 rats. The antitumor effects were evaluated by t...

journal_title：Bulletin of experimental biology and medicine

authors： Bespalov VG,Vyshinskaya EA,Vasil'eva IN,Semenov AL,Maidin MA,Barakova NV,Stukov AN

更新日期：2017-01-01 00:00:00

abstract：:We studied the role of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) in functional differentiation of HC11 mouse mammary gland cells. It was found that both IGF-1 and IGF-2 activate the expression of milk protein β-casein in the presence of prolactin and hydrocortisone. It was found that β-casein expression is...

journal_title：Bulletin of experimental biology and medicine

authors： Shushanov SS

更新日期：2011-12-01 00:00:00

abstract：:We studied the effect of allopregnanolone on stress-induced anxiety caused by intranasal administration of corticoliberin to male Wistar rats. Active and passive rats were selected by their T-maze behavior and then were tested in elevated plus maze for initial anxiety level. Basing on test results, the animals were di...

journal_title：Bulletin of experimental biology and medicine

authors： Semenova OG,Rakitskaya VV

更新日期：2014-04-01 00:00:00

abstract：:High doses of phenylephrine and diazepam (1 and 10 mg/kg, respectively) suppressed the development of generalized tonic-clonic pentylenetetrazole-induced convulsions in 86-100% rats, but did not prevent local clonic pentylenetetrazole-induced convulsions. Diazepam in the specified dose produced strong sedation, while ...

journal_title：Bulletin of experimental biology and medicine

authors： Serdyuk SE,Gmiro VE

更新日期：2014-12-01 00:00:00

abstract：:We studied changes in protein composition and their effects on convulsive activity in drug-induced and electrical kindling. Injection of protein fraction of brain extract from animals subjected to metronidazole-induced kindling to intact recipients reduced their sensitivity to the convulsant (i. e. increased the dose ...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova MN,Karganov MY,Klishina NY,Khlebnikova NN,Kryzhanovskii GN

更新日期：2002-06-01 00:00:00

abstract：:Effects of local therapy with miacalcic on the metabolism in articular connective tissue structures under conditions of experimental arthritis are shown. An effect modifying articular tissue metabolism and an antiinflammatory effect preventing the development of inflammatory destructive processes in rabbit articular t...

journal_title：Bulletin of experimental biology and medicine

authors： Belova SV

更新日期：2007-03-01 00:00:00

abstract：:The resistance of native and circulating modified low-density lipoproteins from human blood to spontaneous and polyethylene glycol-induced association was studied by recording light transmission fluctuations. Circulating modified low-density lipoproteins were less resistant to association than native low-density lipop...

journal_title：Bulletin of experimental biology and medicine

authors： Suprun IV,Mel'nichenko AA,Sobenin IA,Panasenko OM,Orekhov AN

更新日期：2004-10-01 00:00:00

abstract：:GABA, baclofen, isoguvacine increase, and cis-4-aminocrotonic acid does not modify resting membrane potential of muscle cells. Bicuculline, phaclofen, N-ethylmaleimide, chlorpromazine, verapamil, and removal of Ca2+ from bathing solution abolished the effect of baclofen, while U73122 and D609 were ineffective in this ...

journal_title：Bulletin of experimental biology and medicine

authors： Volkov EM,Sabirova AR,Grishin SN,Zefirov AL

更新日期：2005-02-01 00:00:00

abstract：:In mature rats, electrical stimulation of the retrotrapezoid nucleus increased the amplitude and frequency of the high-frequency peak in the firing spectrum of the phrenic nerve, while the amplitude of medium-frequency peak and the amplitude ratio of medium- to high-frequency peaks decreased. These changes in spectral...

journal_title：Bulletin of experimental biology and medicine

authors： Tatarnikov VS

更新日期：2004-08-01 00:00:00

abstract：:Plasma LDL content increased in rats with mild chronic heart failure, but decreased in animals with severe pathology. The lipid profile of β-adrenoceptor antagonists depended on their selectivity. The most selective antagonists of β-adrenoceptors had little effect on the lipid composition. Nonselective β-adrenoceptor ...

journal_title：Bulletin of experimental biology and medicine

authors： Sidorov AV

更新日期：2013-12-01 00:00:00