Resistance of native and circulating modified low-density lipoproteins in human blood to association.

Abstract:

:The resistance of native and circulating modified low-density lipoproteins from human blood to spontaneous and polyethylene glycol-induced association was studied by recording light transmission fluctuations. Circulating modified low-density lipoproteins were less resistant to association than native low-density lipoproteins. Polyethylene glycol-induced association of low-density lipoproteins was irreversible. Our results suggest that atherogenic activity of circulating modified low-density lipoproteins is associated with their increased predisposition to irreversible association.

journal_name

Bull Exp Biol Med

authors

Suprun IV,Mel'nichenko AA,Sobenin IA,Panasenko OM,Orekhov AN

doi

10.1007/s10517-005-0047-2

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

380-3

issue

4

eissn

0007-4888

issn

1573-8221

pii

doi

journal_volume

138

pub_type

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