Effect of low-choline diet and ethanol on electroconductivity of tissues in CBA mice.

abstract：:We studied the role of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) in functional differentiation of HC11 mouse mammary gland cells. It was found that both IGF-1 and IGF-2 activate the expression of milk protein β-casein in the presence of prolactin and hydrocortisone. It was found that β-casein expression is...

journal_title：Bulletin of experimental biology and medicine

authors： Shushanov SS

更新日期：2011-12-01 00:00:00

abstract：:Activities of enzymes of active oxygen forms detoxication and phase II xenobiotic metabolism were measured in rat hepatoma 27 cells transplanted to different organs. Activity of phase II xenobiotic metabolizing enzymes was higher in hepatoma cells growing subcutaneously than in those transplanted into the liver, while...

journal_title：Bulletin of experimental biology and medicine

authors： Ostashkina NM,Dubovaya TK,Koblyakov VA,Konovalova GG,Lankin VZ

更新日期：2000-11-01 00:00:00

abstract：:Morphological changes in the thymus of female Wistar rats with experimental mammary gland carcinomas were studied. After adjuvant therapy, the area of the cortical matter and density of parenchymal cells in the thymus decreased, while areas of the medulla, connective tissue, and content of immunoblasts and macrophages...

journal_title：Bulletin of experimental biology and medicine

authors： Kazakov OV,Kabakov AV,Poveshchenko AF,Ishchenko IY,Poveshchenko OV,Strunkin DN,Raiter TV,Michurina SV,Konenkov VI

更新日期：2017-03-01 00:00:00

abstract：:Experiments on the model of thermal skin burn in rats showed that the use of wound dressing based on collagen-chitosan complex Kollakhit-Bol in local treatment of grade IIIb skin burns increased healing rate by accelerating the formation of granulation and fibrous connective tissues and reducing crust thickness in com...

journal_title：Bulletin of experimental biology and medicine

authors： Kirichenko AK,Bolshakov IN,Ali-Riza AE,Vlasov AA

更新日期：2013-03-01 00:00:00

abstract：:We studied the effect of gold nanospheres coated with components of autologous blood plasma on ADP-induced platelet aggregation. Gold nanoparticles in the chosen concentration range (5-40 μM) and particle size (5-30 nm) with or without coating produced no activating effect on platelet aggregation caused by aggregation...

journal_title：Bulletin of experimental biology and medicine

authors： Aseychev AV,Azizova OA,Beckman EM,Dudnik LB,Sergienko VI

更新日期：2013-09-01 00:00:00

abstract：:The level of antipaternal antileukocytic antibodies detected by flow cytometry is a parameter reflecting the efficiency of alloimmunization of women with reproductive disorders during preparation to pregnancy. The results of evaluation of antipaternal antileukocytic antibodies by two modifications of the method are pr...

journal_title：Bulletin of experimental biology and medicine

authors： Krechetova LV,Nikolaeva MA,Van'ko LV,Ziganshina MM,Golubeva EL,Stepanova EO,Sukhikh GT

更新日期：2012-09-01 00:00:00

abstract：:We studied the effect of 20 standard L-amino acids on proliferation of the nervous, cardiovascular, urogenital, digestive, and immune system tissues from young and old animals in organotypic cultures. The effect of amino acids on tissue culture proliferation depended on their origin and animal age. ...

journal_title：Bulletin of experimental biology and medicine

authors： Chalisova NI,Kontsevaya NE,Linkova NS,Pronyaeva VE,Chervyakova NA,Umnov RS,Benberin VV,Khavinson VH

更新日期：2013-08-01 00:00:00

abstract：:We studied some structural and functional parameters of erythrocyte membranes in mice at the late presymptomatic and early symptomatic stages of experimental Parkinson's disease induced by administration of MPTP (hemolysis, microviscosity of different regions of the lipid bilayer, LPO intensity, activity of antioxidan...

journal_title：Bulletin of experimental biology and medicine

authors： Fatkullina LD,Molochkina EM,Kozachenko AI,Nagler LG,Burlakova EB

更新日期：2017-03-01 00:00:00

abstract：:Castration had no effect on baseline BP and vascular sensitivity to acetylcholine and deficiency of nitric oxide and prostacyclin in normotensive specimens. Castration of hypertensive specimens decreased BP and potentiated the hypotensive effects of acetylcholine, but did not modulate vascular sensitivity to the block...

journal_title：Bulletin of experimental biology and medicine

authors： Semyachkina-Glushkovskaya OV,Anishchenko TG,Kuznetsova AS,Kuznetsova YV,Bibikova OA,Sjestnova AA

更新日期：2012-06-01 00:00:00

abstract：:Intraperitoneal injections of hexavalent chromium (sodium bichromate) in the concentrations of 0.025 μg/kg (10-fold lower than MAC; group 1) and 2.5 μg/kg (10-fold higher than MAC; group 2) to rats in a subacute experiment caused dose-dependent morphological changes in the thymus: increased the counts of cells in a st...

journal_title：Bulletin of experimental biology and medicine

authors： Zhumabaeva AN,Zarishnyak NV,Bekmukhambetov EZh

更新日期：2014-02-01 00:00:00

abstract：:The effects of glucocorticoids on monocyte morphology and function in vitro and the results of high-dose budesonide therapy in patients with non-severe bronchial asthma were analyzed. Before therapy with inhalation glucocorticosteroid (budesonide) characteristics of blood monocytes and the effects of different concent...

journal_title：Bulletin of experimental biology and medicine

authors： Terpigorev SA,Il'chenko VA,Vasilenko IA,Slinchenko OI,Stotskaya TV,Markina TR,Paleev NR

更新日期：2003-06-01 00:00:00

abstract：:Transplantation of human bone marrow mesenchymal stem cells is considered as a promising therapeutic approach to the therapy of many diseases. However, the problem of possible alterations of the properties of mesenchymal stem cells during their expansion in in vitro cultures before transplantation is not solved. In ou...

journal_title：Bulletin of experimental biology and medicine

authors： Grigorian AS,Kruglyakov PV,Taminkina UA,Efimova OA,Pendina AA,Voskresenskaya AV,Kuznetsova TV,Polyntsev DG

更新日期：2010-12-01 00:00:00

abstract：:We studied functional activity of neutrophilic granulocytes and monocytes isolated from the peripheral blood of women during the follicular and luteal phases of the menstrual cycle. It was shown that phagocytic activity of neutrophilic granulocytes increases, their intracellular oxygen-dependent bactericidal activity ...

journal_title：Bulletin of experimental biology and medicine

authors： Smirnova TG,Savochkina AY,Dolgushin II,Nikushkina KV,Samuseva IV

更新日期：2018-12-01 00:00:00

abstract：:We studied ultrastructural reorganization of the colon transplant in delayed period after esophagoplasty. It was found that during functioning of the artificial esophagus, a complex of adaptive and pathologic processes occurs in the mucosa. Focal sclerosis of the mucosa and slight epithelial degeneration with hyperpla...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh LM,Lapii GA,Chikinev YV,Sudovykh IE,Tokmakov IA

更新日期：2012-06-01 00:00:00

abstract：:We studied the effect of zoledronic acid encapsulated into liposomes (L-ZOL) on tumorassociated macrophages in the stroma of hepatocellular carcinoma xenograft. Liposomes were prepared from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, 1,2-dipalmitoyl-snglycero-3-phospho-sn-1-glycerol, and 1,2-distearoyl-sn-glycero-3-p...

journal_title：Bulletin of experimental biology and medicine

authors： Wu S,Lin X,Cui X

更新日期：2020-11-01 00:00:00

abstract：:Here we present the results of histochemical detection of 3β-hydroxysteroid dehydrogenase in neurons of the neocortex, cerebellum, and brainstem. The positive reaction was observed in a low number of neocortical, midbrain, and pontine neurons. The maximum number of positive neurons was detected in the cerebellar corte...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva VM

更新日期：2012-01-01 00:00:00

abstract：:We studied the expression of genes encoding angiotensinogen (Agt), renin (Ren), angiotensin-converting enzyme (ACE), and type 1 angiotensin receptor (AT1A) in the hypothalamus and medulla oblongata of hypertensive ISIAH rats and normotensive WAG rats. The amount of Agt mRNA in the hypothalamus of young ISIAH rats was ...

journal_title：Bulletin of experimental biology and medicine

authors： Klimov LO,Fedoseeva LA,Ryazanova MA,Dymshits GM,Markel AL

更新日期：2013-01-01 00:00:00

abstract：:Effect of afobazole on the threshold of electrical fibrillation of the heart was studied on anesthetized rats with intact myocardium. It was shown that the drug considerably increased the threshold of electrical fibrillation of the heart, being not inferior to reference class I antiarrhythmic drugs (lidocaine and proc...

journal_title：Bulletin of experimental biology and medicine

authors： Kryzhanovskyi SA,Stolyaruck VN,Vititnova MB,Tsorin IB,Seredenin SB

更新日期：2010-09-01 00:00:00

abstract：:We studied the effect of anti-inflammatory cytokine IL-4 (5 μg/kg intraperitoneally) on peripheral blood leukocytes in Wistar rats with various behavioral characteristics during acute emotional stress (1-h immobilization with simultaneous subthreshold electrocutaneous stimulation). IL-4 reduced the differences in bloo...

journal_title：Bulletin of experimental biology and medicine

authors： Pertsov SS,Koplik EV,Kalinichenko LS

更新日期：2015-03-01 00:00:00

abstract：:Serum activity of tartrate-resistant acid phosphatase 5b (TRAP 5b) in patients with breast cancer and prostate cancer having bone metastases was much higher than in healthy donors and patients without skeletal injuries. TRAP 5b activity in patients with breast cancer and multiple bone metastases surpassed that in pati...

journal_title：Bulletin of experimental biology and medicine

authors： Lyubimova NV,Pashkov MV,Tyulyandin SA,Gol'dberg VE,Kushlinskii NE

更新日期：2004-07-01 00:00:00

abstract：:The incidence of 5 polymorphisms of N-acetyltransferase-2 gene was evaluated in patients with lung cancer. A803G polymorphism is a factor of lung cancer resistance in tobacco smoking Caucasians in Novosibirsk. Opposite effects of NAT2 gene polymorphisms on the risk of lung cancer are possible. ...

journal_title：Bulletin of experimental biology and medicine

authors： Nikishina MV,Vavilin VA,Makarova SI,Lyakhovich VV

更新日期：2007-01-01 00:00:00

abstract：:The development and manufacturing of serum-free culture media allowing reducing the costs of preparations and standardizing the biotechnological process are important trends in biotechnology. Substitution of protein compounds in the serum-free media with recombinant analogues reduces the risk of contamination with var...

journal_title：Bulletin of experimental biology and medicine

authors： Bobik TV,Popov RY,Aliev TK,Mokrushina YA,Shamborant OG,Khurs EN,Knorre VD,Smirnov IV,Gabibov AG

更新日期：2019-07-01 00:00:00

abstract：:The rates of oxyhemoglobin drop and CO(2) release in dogs with magnetized and nonmagnetized blood were compared. Stationary magnetic field enhances blood oxygen capacity by no less than 24%. A hypothesis was proposed on formation of bioxyhemoglobin molecules under the effect of magnetic field, in which hem binds two O...

journal_title：Bulletin of experimental biology and medicine

authors： Zhernovoi AI,Skorik VI,Chirukhin VA,Sharshina LM

更新日期：2001-02-01 00:00:00

abstract：:A combination of electrochemical lysis and photodynamic therapy were used to attain complete resorption of M-1 sarcoma in rats; both treatment modalities were used with minimum parameters. Fotolon served as the photosensitizer for photodynamic therapy. Accumulation of the sensitizer in the tumor and normal tissue was ...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhailovskaya AA,Kaplan MA,Brodskij RA,Bandurko LN

更新日期：2009-01-01 00:00:00

abstract：:We studied anticonvulsant effects of combined treatment with citicoline, a nootropic substance with neuroregenerative and neuroprotective activities, and valproate, an antiepileptic agent widely used in the treatment of epilepsy, on the model of pentylenetetrazole-induced (75 mg/kg, intraperitoneally) acute generalize...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova MN,Kuznetsova LV,Zin'kovskii KA,Klishina NV

更新日期：2016-02-01 00:00:00

abstract：:Experiments on rats showed that high-intensity light exposure (6000 lux, 6 h) caused focal injuries in the retina. The most sensitive structures were neurosensory cells, pigmented epithelium, radial gliocytes, and choroid capillaries. Injection of ascovertin led to disappearance of foci of injuries, limited blood supp...

journal_title：Bulletin of experimental biology and medicine

authors： Logvinov SV,Plotnikov MB,Varakuta EY,Zhdankina AA,Potapov AV,Mikhulya EP

更新日期：2005-11-01 00:00:00

abstract：:Over many years, tick-borne infections remain one of the most serious threats to human health worldwide. The immune response to these infections in a human after confirmed bite by an infected carrier at the early stages of infection in the absence of clinical symptoms can be the first indicator of the presence of the ...

journal_title：Bulletin of experimental biology and medicine

authors： Danchinova GA,Khasnatinov MA,Lyapunova NA,Solovarov IS,Manzarova EL,Lyapunov AV,Petrova IV

更新日期：2019-03-01 00:00:00

abstract：:Electron microscopic study of changes in cultured cells caused by Vibrio cholerae recombinant hemagglutinin/protease (HA/P) showed significant structural changes, most pronounced in HeLa and L-929 cells not forming a compact monolayer with tight junctions between the cells: formation of numerous vesicles on the cell s...

journal_title：Bulletin of experimental biology and medicine

authors： Sayamov SR,Monakhova EV,Fedorenko GM,Tkacheva TI,Markina OV,Alekseeva LP,Pisanov RV,Bardakhchian EA

更新日期：2012-02-01 00:00:00

abstract：:We studied the effects of cholesterol, its oxidized derivatives mevalonate, and nuclear receptor agonists LXR, RXR, and FXR on the production of transforming growth factor-beta1 (TGF- beta1) by macrophages. After recruiting of macrophage monocytes into the focus of inflammation, the production of TGF-beta1 increased b...

journal_title：Bulletin of experimental biology and medicine

authors： Schwartz YSh,Khoshchenko OM,Dushkin MI,Feofanova NA

更新日期：2009-09-01 00:00:00

abstract：:The location and level of IL-8 and TGF-beta2 expression in the fimbrial compartment of fallopian tubes and IL-10 expression in the endometrium of women with pyoinflammatory adnexal diseases were studied by in situ hybridization. These diseases are associated with considerable changes in the levels of local production ...

journal_title：Bulletin of experimental biology and medicine

authors： Zhdanov AV,Kurbanova DF,Sosulina LY,Davydova MP,Ezhova LS,Sukhikh GT

更新日期：2003-03-01 00:00:00