Selective Cytotoxicity of Manganese Nanoparticles against Human Glioblastoma Cells.

abstract：:Pronounced antitumor effect of Thymalin in doses lower than the therapeutic doses was shown in experiments on albino outbred male rats with transplanted sarcoma 45. Tumor growth arrest and its regression were observed in more than half of animals and in other cases, the growth was suppressed by 78%. Microstructural ch...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova GV,Schikhlyarova AI,Barteneva TA,Shevchenko AN,Zakharyuta FM

更新日期：2018-05-01 00:00:00

abstract：:The effects of cerivastatin on antiatherogenic properties of high-density lipoproteins were studied in patients with coronary heart disease and hyperlipidemia. Apart from hypolipidemic effects, cerivastatin changed the phospholipid composition of high-density lipoproteins and improved their cholesterol-acceptor proper...

journal_title：Bulletin of experimental biology and medicine

authors： Ozerova IN,Jeevan DM,Serdyuk AP,Paramonova IV,Akhmedzhanov NM,Metel'skaya VA,Perova NV

更新日期：2000-10-01 00:00:00

abstract：:Micro- and nanomolar concentrations of ganglioside GM1 improved viability of neuronal PC12 cells under conditions of oxidative stress and reduced H2O2-induced ROS accumulation in these cells. These effects were more pronounced at micromolar concentrations. GM1 in concentrations of 100 nM and 10 μM significantly and su...

journal_title：Bulletin of experimental biology and medicine

authors： Zakharova IO,Sokolova TV,Akhmetshina AO,Avrova NF

更新日期：2015-09-01 00:00:00

abstract：:The antiamnestic effects of tenoten (pediatric formulation) was demonstrated on the model of scopolamine-induced amnesia of passive avoidance reflex and the nootropic effect of this preparation was demonstrated on the model of incomplete conditioning and in rat pups with experimental attention deficit syndrome. The ef...

journal_title：Bulletin of experimental biology and medicine

authors： Voronina TA,Molodavkin GM,Borodavkina MV,Kheyfets IA,Dugina YL,Sergeeva SA

更新日期：2009-09-01 00:00:00

abstract：:The absence of negative effects of anoceptin on the liver tissue and detoxifying function was proven experimentally in vitro and in vivo. It was proven for the first time that comenic acid (anoceptin active substance) in concentrations of 10(-4)-10(-12) does not modulate the growth of liver explants from 10-12-day chi...

journal_title：Bulletin of experimental biology and medicine

authors： Kipenko AV,Penniyaynen VA,Lopatina EV,Tsyrlin VA,Lobov GI,Krylov BV

更新日期：2010-12-01 00:00:00

abstract：:The effects of ladasten and reference product imipramine (10 mg/kg) on the content of cytokines TNF-α, IL-6, IL-10, IL-1α, IL-2, IL-4, IL-5, IL-17, IFN-γ, and GM-CSF and behavior of male C57Bl/6 mice were studied on the model of a depression-like state induced by a single intraperitoneal injection of bacterial LPS in ...

journal_title：Bulletin of experimental biology and medicine

authors： Tallerova AV,Kovalenko LP,Durnev AD,Seredenin SB

更新日期：2011-11-01 00:00:00

abstract：:We revealed a significant positive correlation between the concentrations of tissue VEGF and its receptor VEGFR2 in the primary tumor. The degree and direction of changes in the content of VEGF and VEGFR2 in cytosols of tumors from patients with locally spread breast cancer during the preoperation therapy depended on ...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EA,Gershtein ES,Vysotskaya IV,Kushlinskii NE

更新日期：2008-02-01 00:00:00

abstract：:Modification of apolipoprotein B-100 conformation on the surface of LDL isolated from human blood was demonstrated by enzyme immunoassay with a panel of monoclonal antibodies to this protein. The study by the light transmission fluctuation method showed that incubation of LDL with phospholipases A2 or C led to associa...

journal_title：Bulletin of experimental biology and medicine

authors： Aksenov DV,Mel'nichenko AA,Suprun IV,Yanushevskaya EV,Vlasik TN,Sobenin IA,Panasenko OM,Orekhov AN

更新日期：2005-10-01 00:00:00

abstract：:Patch-clamp and concentration jump studies showed that gadolinium ions dose-dependently reduced the amplitude of proton-activated currents (pH 6.5) in isolated Purkinje cells (gadolinium concentration producing a half-maximum effect was 69 microM for the peak and 8 microM for the stationary component of the current). ...

journal_title：Bulletin of experimental biology and medicine

authors： Sharonova IN,Dvorzhak AY,Vorobjov VS

更新日期：2008-03-01 00:00:00

abstract：:Silicon crystal 2-5 nm nanoparticles in the form of 1-5-μ granules in water suspension were injected intraperitoneally in a single dose to male F(1)(CBA×C57Bl/6) mice or to outbred albino rats on days 1, 7, and 14 of gestation. Silicon crystal nanoparticles in doses of 5, 25, and 50 mg/kg exhibited no cytogenetic acti...

journal_title：Bulletin of experimental biology and medicine

authors： Durnev AD,Solomina AS,Daugel-Dauge NO,Zhanataev AK,Shreder ED,Nemova EP,Shreder OV,Veligura VA,Osminkina LA,Timoshenko VY,Seredenin SB

更新日期：2010-10-01 00:00:00

abstract：:A simple method for the diagnosis of insulin resistance, easily realized in clinical practice, is developed in order to detect patients at a high risk of diseases associated with this condition. The metabolic index is estimated as the proportion of triglycerides and glucose values to quadratic HDL cholesterol value (i...

journal_title：Bulletin of experimental biology and medicine

authors： Roitberg GE,Dorosh ZhV,Sharkhun OO

更新日期：2015-01-01 00:00:00

abstract：:Experimental simulation of burn was followed by accumulation of LPO products and suppression of antioxidant enzyme activity in the burn wound. Application of a synthetic analogue of indolicidin led to an increase in MDA and acylhydroperoxide concentrations in the burn wound on experimental day 1. Further application o...

journal_title：Bulletin of experimental biology and medicine

authors： Lazarenko VA,Lyashev YD,Shevchenko NI

更新日期：2014-08-01 00:00:00

abstract：:Experiments on rats showed that blockade of norepinephrine reuptake in the early reperfusion period after focal myocardial ischemia aggravates myocardial injury and abolishes the protective effect of ischemic preconditioning. ...

journal_title：Bulletin of experimental biology and medicine

authors： Naumenko SE,Latysheva TV,Gilinskii MA

更新日期：2010-12-01 00:00:00

abstract：:Cytochemical activity of succinate dehydrogenase and lactate dehydrogenase in blood lymphocytes, activity of hydroperoxides, MDA, and blood plasma antioxidants were studied in experimental animals during immobilization stress after preliminary injection of doxazosin. Preliminary adrenergic receptor blockade prevented ...

journal_title：Bulletin of experimental biology and medicine

authors： Vishnevskii EL,Vishnevskii AE,Shabel'nikova EI,Safronova ON,Dreval AA,Topchieva GV,Sukhorukov VS

更新日期：2004-11-01 00:00:00

abstract：:"Therapeutic Effects of Salidroside on Cognitive Ability in Rats with Experimental Vascular Dementia," by Z. Tian, Yu. Li, G. Wang, J. Wang, and Ye. Zhang, Vol. 169, No. 1, pp. 35-39, May 2020. ...

journal_title：Bulletin of experimental biology and medicine

authors： Tian Z,Li Y,Wang G,Wang J,Zhang Y

更新日期：2020-06-01 00:00:00

abstract：:The dependence of daily vitamin excretion with breast milk on dietary vitamin content and blood vitamin level was studied in nursing women. Breast mils vitamins were assayed in women supplied with vitamins. We identified the criteria for adequate vitamin supply in nursing women over the 1st month after labor (vitamins...

journal_title：Bulletin of experimental biology and medicine

authors： Kodentsova VM,Vrzhesinskaya OA

更新日期：2006-03-01 00:00:00

abstract：:The tissue engineering construction was developed from human bone marrow multipotent stromal cells and 3D porous foamed-ceramic carriers of a zirconium oxide-aluminum oxide system. The carriers had no cytotoxic activity and were potent in maintaining the cell adhesion and proliferation. We developed the method for ino...

journal_title：Bulletin of experimental biology and medicine

authors： Bukharova TB,Fatkhudinov TKh,Tsedik LV,Ilyushchenko AF,Goldshtein DV

更新日期：2009-01-01 00:00:00

abstract：:Analysis of contribution of sympathetic and parasympathetic systems into heart rate variability carried out using atenolol and atropine showed that August rats are characterized by enhanced tone of the sympathetic system and reduced tone of the parasympathetic system compared to Wistar rats. Reduced tone of the parasy...

journal_title：Bulletin of experimental biology and medicine

authors： Kirillina TN,Usacheva MA,Belkina LM

更新日期：2006-10-01 00:00:00

abstract：:Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level foll...

journal_title：Bulletin of experimental biology and medicine

authors： Kuznetsova NV,Palchikova NA,Selyatitskaya VG,Shkurupiy VA

更新日期：2010-11-01 00:00:00

abstract：:Olivomycin (DNA-binding antibiotic) in nanomolar concentrations induces apoptosis of human tumor cells and inhibits p53-dependent transcription of the reporter gene (basal and induced by antitumor drugs). Olivomycin aglycon induces no cytotoxicity and does not block transcription. ...

journal_title：Bulletin of experimental biology and medicine

authors： Simonova VS,Samusenko AV,Filippova NA,Tevyashova AN,Lyniv LS,Kulik GI,Chekhun VF,Shtil AA

更新日期：2005-04-01 00:00:00

abstract：:Plasma concentration of immune complexes and antibodies to serotonin and dopamine were higher in patients with Alzheimer's disease compared to mentally healthy volunteers of the same age. Plasma concentrations of antibodies to serotonin and dopamine decreased with the increase in the duration of this disease. ...

journal_title：Bulletin of experimental biology and medicine

authors： Davydova TV,Mikovskaya OI,Fomina VG,Voskresenskaya NI,Doronina OA

更新日期：2002-07-01 00:00:00

abstract：:Apoptosis markers (p53, PUMA, p21, and Mdm2) were studied in patients with rheumatoid arthritis at the early and late stages of disease on bone marrow smears and frozen sections of the articular synovial membrane. The target molecules were found in all patients. The early stage was characterized by maximum expression ...

journal_title：Bulletin of experimental biology and medicine

authors： Doroshevskaya AY,Kondratovskii PM,Dubikov AI,Eliseikina MG

更新日期：2014-01-01 00:00:00

abstract：:We evaluated normal blood glucose levels in two species of monkeys, namely rhesus monkeys (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis) kept in the Breeding Center of the Institute of Medical Primatology. The animals were either under moderate stress due to catching or after recovery of defensive and ...

journal_title：Bulletin of experimental biology and medicine

authors： Lapin BA,Gvozdik TE,Klots IN

更新日期：2013-02-01 00:00:00

abstract：:Cardiac and plasma activities of marker lysosomal enzymes were studied in Wistar rats with metabolic (epinephrine) and occlusion (ligation of coronary arteries) myocardial infarction. Activity of all examined lysosomal enzymes significantly increased in the myocardium and blood plasma starting from the first day after...

journal_title：Bulletin of experimental biology and medicine

authors： Mayanskaya SD,Mayanskaya NN,Efremov AV,Yakobson GS

更新日期：2000-06-01 00:00:00

abstract：:Age-associated changes in the concentrations of glucose, insulin, and DHEAS in peripheral blood plasma of female rhesus macaques were studied in intact animals and in response to a standard dose of glucose and insulin. Basal levels of insulin and glucose increased, insulin sensitivity and glucose tolerance decreased, ...

journal_title：Bulletin of experimental biology and medicine

authors： Goncharova ND,Vengerin AA,Oganyan TE,Lapin BA

更新日期：2004-03-01 00:00:00

abstract：:Burn trauma increased blood chemiluminescence, while lipopolysaccharide in a dose of 1 mg/kg potentiated this effect, activated LPO, and decreased plasma antioxidant activity. In erythrocytes, superoxide dismutase activity increased, while activity of peroxide-utilizing enzymes decreased. Myeloperoxidase content incre...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhal'chik EV,Titkova SM,Anurov MV,Ettinger AP,Korkina LG

更新日期：2006-06-01 00:00:00

abstract：:The rates of oxyhemoglobin drop and CO(2) release in dogs with magnetized and nonmagnetized blood were compared. Stationary magnetic field enhances blood oxygen capacity by no less than 24%. A hypothesis was proposed on formation of bioxyhemoglobin molecules under the effect of magnetic field, in which hem binds two O...

journal_title：Bulletin of experimental biology and medicine

authors： Zhernovoi AI,Skorik VI,Chirukhin VA,Sharshina LM

更新日期：2001-02-01 00:00:00

abstract：:Comparative identification of cerebral regions activated in men and women during perception of indefinite images was carried out by fMRT and psychological testing. Nine men and nine women aged 20-26 years took part in the study. The volunteers examined simple geometric figures, slightly structurized images (tables fro...

journal_title：Bulletin of experimental biology and medicine

authors： Fyodorov AA,Pervushina ON,Bliznyuk MV,Khoroshilov BM,Melnikov ME,Mazhirina KG,Stark MB,Savelov AA,Petrovsky ED,Kozlova LI

更新日期：2016-07-01 00:00:00

abstract：:Fifty-three transplantations of pituitary tissue (intact and minced with scissors) under the tunica albuginea testis were carried out. In both series pituitary cells retained viability for up to 6 months. Transplantation of cell suspension was not accompanied by the formation of necrotic zone in the transplant; the ad...

journal_title：Bulletin of experimental biology and medicine

authors： Dendeberov ES

更新日期：2001-02-01 00:00:00

abstract：:The study examined the effect of H2S on the tone of cerebral arteries in rats after global cerebral ischemia/reperfusion injury and cooperation between NO and H2S in the control over cerebral circulation during the postischemic period. In control sham-operated and in experimental rats with ischemia/reperfusion injury,...

journal_title：Bulletin of experimental biology and medicine

authors： Lobov GI,Sokolova IB,Gorshkova OP,Shvetsova ME,Dvoretskii DP

更新日期：2020-03-01 00:00:00