Parameters of cell energy metabolism during stress in laboratory animals and energotropic effect of alpha1-adrenoblocker doxazosin.

Abstract:

:Cytochemical activity of succinate dehydrogenase and lactate dehydrogenase in blood lymphocytes, activity of hydroperoxides, MDA, and blood plasma antioxidants were studied in experimental animals during immobilization stress after preliminary injection of doxazosin. Preliminary adrenergic receptor blockade prevented changes in cell metabolism characteristic of immobilization stress. The role of adrenergic regulation in the realization of energotropic effects during immobilization stress was examined.

journal_name

Bull Exp Biol Med

authors

Vishnevskii EL,Vishnevskii AE,Shabel'nikova EI,Safronova ON,Dreval AA,Topchieva GV,Sukhorukov VS

doi

10.1007/s10517-005-0064-1

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

440-1

issue

5

eissn

0007-4888

issn

1573-8221

pii

doi

journal_volume

138

pub_type

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