Comparative effect of amphetamine and caffeine on spontaneous activity of sensomotor cortical units and their responses to stimulation of the caudate nucleus.

Abstract:

:In acute experiments on anesthetized cats activity of sensomotor cortical units was recorded during low-frequency stimulation of the head of the caudate nucleus. Amphetamine (1 mg/kg), although not significantly affecting the spontaneous firing rate, increased the number of spontaneously active cortical units. Meanwhile inhibition of these units during stimulation of the caudate nucleus was weakened. Amphetamine had a stronger suppressive action on the inhibition arising from the ventro-lateral portion than from the dorso-medial portion of the head. In the case of caffeine the location of the stimulating electrodes was unimportant.

journal_name

Bull Exp Biol Med

authors

Arushanyan EB,Belozertsev YA,Aivazov KG

doi

10.1007/BF00799317

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

776-9

issue

7

eissn

0007-4888

issn

1573-8221

journal_volume

77

pub_type

杂志文章
  • Changes in granulocytic hemopoietic stem and their mechanisms during hypoxia of different genesis.

    abstract::We studied reactions of the granulocytic hemopoietic stem during hypoxia of different genesis and severity. Stimulation of granulocytopoiesis was determined by an increase in functional activity of granulomonocytic precursors due to changes in feeder capacity of cells in the hemopoiesis-inducing microenvironment and c...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-005-0271-9

    authors: Zyuz'kov GN,Dygai AM,Gol'dberg ED

    更新日期:2005-03-01 00:00:00

  • Antiaggregant activity of a new benzimidazole derivative.

    abstract::Antiaggregant activity of a new tricyclic benzimidazole derivative, RU-891 compound, was studied on the model of ADP-induced platelet aggregation in vitro and intravascular platelet aggregation in vivo. We evaluated the effect of this substance on blood coagulation potential. Antiaggregant agent acetylsalicylic acid w...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-014-2453-9

    authors: Kucheryavenko AF,Spasov AA,Petrov VI,Anisimova VA

    更新日期:2014-04-01 00:00:00

  • Ultrastructural study of cell populations in the gastric transplant after esophagoplasty.

    abstract::Ultrastructural characteristics of cell populations in the gastric tube mucosa were studied after plastic surgery for benign esophageal disease. The foveolar epithelium mainly consisted of secretory active mucocytes with small changes in cytoplasmic organelles. Functionally immature parietal cells and gland cells in t...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-011-1175-5

    authors: Lapii GA,Nepomnyashchikh LM,Sudovykh IE,Kutepov AV,Govorkov RV

    更新日期:2011-02-01 00:00:00

  • Electron microscopy of rat liver after intravenous injection of nanosized magnetite suspension.

    abstract::Rat liver was examined by transmission electron microscopy after a single intravenous injection of nanosized magnetite suspension (0.1 g (Fe(3)O(4))/kg body weight). Magnetite particles were found in Kupffer's cells and hepatocytes. Accumulation of the particles by these two cell types was different. Morphometry of ma...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-012-1756-y

    authors: Mil'to IV,Sukhodolo IV,Miller AA

    更新日期:2012-08-01 00:00:00

  • Spectral parameters of phrenic nerve activity in mature rats during electrical stimulation of retrotrapezoid nucleus.

    abstract::In mature rats, electrical stimulation of the retrotrapezoid nucleus increased the amplitude and frequency of the high-frequency peak in the firing spectrum of the phrenic nerve, while the amplitude of medium-frequency peak and the amplitude ratio of medium- to high-frequency peaks decreased. These changes in spectral...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1023/b:bebm.0000048366.73882.49

    authors: Tatarnikov VS

    更新日期:2004-08-01 00:00:00

  • Hypochlorite, oxidative modification of plasma lipoproteins, and atherosclerosis.

    abstract::Hypochlorite produced in vivo by activated neutrophils, monocytes, and macrophages modifies blood lipoproteins and intensifies free radical lipid peroxidation, which probably plays a key role in the early stages of atherosclerotic vascular damages. ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章,评审

    doi:10.1023/a:1017926309665

    authors: Panasenko OM,Sergienko VI

    更新日期:2001-05-01 00:00:00

  • Morphofunctional Changes in the Thyroid Gland of Pubertal and Postpubertal Rats Exposed to Low Dose of DDT.

    abstract::Consumption of low dose DDT from birth until puberty suppressed functional activity of the thyroid gland in rats and leads to destructive changes in the organ during the postpubertal period with compensatory stimulation of secretory activity of thyrocytes aimed at normalization of thyroxin production. ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-016-3590-0

    authors: Yaglova NV,Sledneva YP,Yaglov VV

    更新日期:2016-12-01 00:00:00

  • Effect of Liposome-Encapsulated Zoledronic Acid on Microenvironment of Hepatocellular Carcinoma May Depend on the Ratio Between M1 and M2 Polarized Macrophages.

    abstract::We studied the effect of zoledronic acid encapsulated into liposomes (L-ZOL) on tumorassociated macrophages in the stroma of hepatocellular carcinoma xenograft. Liposomes were prepared from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, 1,2-dipalmitoyl-snglycero-3-phospho-sn-1-glycerol, and 1,2-distearoyl-sn-glycero-3-p...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-020-05006-1

    authors: Wu S,Lin X,Cui X

    更新日期:2020-11-01 00:00:00

  • Brain-Derived Neurotrophic Factor (BDNF) As a Regulator of Apoptosis under Conditions of Focal Experimental Stroke.

    abstract::The immunolocalization of apoptotic factors in rat neocortex was studied on the model of permanent occlusion of the middle cerebral artery with administration of exogenous BDNF. We revealed heterogeneous distribution of pro- and anti-apoptotic factors in the stroke area and in the surrounding penumbra, where caspase-3...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-020-04959-7

    authors: Kalinichenko SG,Matveeva NY,Korobtsov AV

    更新日期:2020-09-01 00:00:00

  • Possible role of slow sodium-calcium channels in the mechanism of changes in electrical and mechanical activity of guinea pig heart cells in local anaphylaxis (the isoptine effects).

    abstract::The local anaphylactic reaction and the effects of histamine during blocking of the slow sodium-calcium channels by isoptine were investigated in the spontaneously contracting oracle of the atrium of a guinea pig previously sensitized to egg albumin. Simultaneously with the intracellular recording of the potentials, i...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/BF00799305

    authors: Khodorov BI,Voronovitskii EG,Ignat'eva VB

    更新日期:1975-01-01 00:00:00

  • Morphofunctional characteristics of fetoplacental barrier of placental villi during pregnancy complicated by herpes-virus infection.

    abstract::Analysis of placenta homogenate from pregnant women having an episode of herpes-virus infection during the third trimester revealed suppression of Bcl-2 protein activity and increase in caspase 3 concentration. Activity of Bcl-2 protein decreases with increasing the titer of antibodies to herpes virus. Increased caspa...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-010-0987-z

    authors: Lutsenko MT,Andrievskaya IA

    更新日期:2010-10-01 00:00:00

  • Selective cannabinoid receptor agonist HU-210 decreases pump function of isolated perfused heart: role of cAMP and cGMP.

    abstract::The rate and strength of heart contractions decreased after 10-min perfusion of rat myocardium with Krebs-Henseleit solution containing a selective cannabinoid receptor agonist HU-210 in a final concentration of 10 nM. HU-210 completely blocked the positive inotropic and chronotropic effect of beta-adrenoceptor agonis...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-005-0123-7

    authors: Maslov LN,Lasukova OV,Krylatov AV,Uzhachenko RV,Pertwee R

    更新日期:2004-12-01 00:00:00

  • On the common mechanisms of cambial somatic and sex cells proliferation and the notion of the cambial cells.

    abstract::Study of the early embryogenesis process based on the previously suggested scheme of epithelial cambial cell work has shown that cambial (or stem) cells originate from the primary ectoderm and intensely express RhoA protein and slightly express Src kinase. This explains their stem properties and the absence of differe...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-012-1649-0

    authors: Yavisheva TM,Shcherbakov SD

    更新日期:2012-05-01 00:00:00

  • Olivomycin induces tumor cell apoptosis and suppresses p53-induced transcription.

    abstract::Olivomycin (DNA-binding antibiotic) in nanomolar concentrations induces apoptosis of human tumor cells and inhibits p53-dependent transcription of the reporter gene (basal and induced by antitumor drugs). Olivomycin aglycon induces no cytotoxicity and does not block transcription. ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-005-0321-3

    authors: Simonova VS,Samusenko AV,Filippova NA,Tevyashova AN,Lyniv LS,Kulik GI,Chekhun VF,Shtil AA

    更新日期:2005-04-01 00:00:00

  • Age-associated changes in hormonal function of the pancreas and regulation of blood glucose in monkeys.

    abstract::Age-associated changes in the concentrations of glucose, insulin, and DHEAS in peripheral blood plasma of female rhesus macaques were studied in intact animals and in response to a standard dose of glucose and insulin. Basal levels of insulin and glucose increased, insulin sensitivity and glucose tolerance decreased, ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1023/b:bebm.0000031570.81043.f9

    authors: Goncharova ND,Vengerin AA,Oganyan TE,Lapin BA

    更新日期:2004-03-01 00:00:00

  • Model for alternative splicing of insulin receptor in myotonic dystrophy type 1.

    abstract::Muscular dystrophy is a common multisystem disease, which results from the impairment of alternative splicing. An increase in the number of unstable CTG and CCTG repeats in untranslated regions of the DMPK and ZNF9 genes is followed by dysregulation of RNA-binding proteins. Further changes are followed by dysfunction ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-009-0611-2

    authors: Tonevitsky EA,Trushkin EV

    更新日期:2009-06-01 00:00:00

  • Intraperitoneal Administration of Muramyl Dipeptide β-Heptylglycoside to Pregnant and Non-Pregnant Female Mice Modulates Production of Th1/Th2/Th17/Tr1 Cytokines by Splenocytes Ex Vivo.

    abstract::Muramyl dipeptide β-heptylglycoside (C7MDP) was administered to non-pregnant CBA female mice and pregnant mice after non-abortion-prone mating (CBA×BALB/c) and mating associated with a high rate of spontaneous abortion (CBA×DBA/2). In non-pregnant females, C7MDP increased the production of IL-2, IL-4, IL-5, IL-6, IL-1...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-015-2888-7

    authors: Kalyuzhin OV,Artem'eva KA,Boltovskaya MN,Bunyatyan KA,Inviyayeva EV,Vinnitskii LI,Karaulov AV

    更新日期:2015-05-01 00:00:00

  • Reflections of hunger and satiation in the structure of temporal organization of slow electrical and spike activities of fundal and antral stomach muscles in rabbits.

    abstract::Manifestations of hunger and satiation in myoelectric activity patterns in different portions of the stomach were studied in chronic experiments. The state of hunger manifested in the structure of temporal organization of slow electric activity of muscles in the stomach body and antrum in the form of bimodal distribut...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-012-1864-8

    authors: Kromin AA,Zenina OY

    更新日期:2012-11-01 00:00:00

  • Hemostimulating effects of erythropoietin immobilized by the nanotechnology method of electron-beam synthesis.

    abstract::The hemostimulating effect of erythropoietin immobilized by the nanotechnology method of electron-beam synthesis was studied on the model of carboplatin-induced myelosuppression. Subcutaneous injection or oral administration of immobilized erythropoietin was followed by stimulation of erythropoiesis. The effect was mo...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-011-1299-7

    authors: Dygai AM,Zyuz'kov GN,Zhdanov VV,Artamonov AV,Bekarev AA,Madonov PG,Kinsht DN,Udut EV,Miroshnichenko LA,Khrichkova TY,Simanina EV,Stavrova LA,Chaikovskiy AV,Markova TS,Minakova MY

    更新日期:2011-06-01 00:00:00

  • Macrophage-granulocyte colony-stimulating factor and fibroblast growth factor in the blood of patients with hyperlipoproteinemia.

    abstract::Solid-phase ELISA revealed increased content of macrophage-granulocyte colony-stimulating factor and basic fibroblast growth factor in the serum of hyperlipoproteinemic patients. ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1023/a:1023815714017

    authors: Saburova OS,Tvorogova MG,Soboleva EL

    更新日期:2003-02-01 00:00:00

  • Reactivity of the immune system and activities of PPARα and PPARγ in the liver under conditions of LPS-induced acute inflammatory response in hypertensive ISIAH rats.

    abstract::The effects of LPS from E. coli on DNA-binding activities of PPARα and PPARγ in the liver and immune system parameters of were studied in hypertensive ISIAH rats and normotensive WAG rats. In ISIAH rats characterized by low basal level of PPARα, PPARγ, and HDL, the response of the peripheral immune system compartment ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-013-2167-4

    authors: Shurligina AV,Dushkin MI,Melnikova EV,Panteleeva NG,Tenditnik MV,Chrapova MV,Trufakin VA

    更新日期:2013-08-01 00:00:00

  • Parameters of cell energy metabolism during stress in laboratory animals and energotropic effect of alpha1-adrenoblocker doxazosin.

    abstract::Cytochemical activity of succinate dehydrogenase and lactate dehydrogenase in blood lymphocytes, activity of hydroperoxides, MDA, and blood plasma antioxidants were studied in experimental animals during immobilization stress after preliminary injection of doxazosin. Preliminary adrenergic receptor blockade prevented ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-005-0064-1

    authors: Vishnevskii EL,Vishnevskii AE,Shabel'nikova EI,Safronova ON,Dreval AA,Topchieva GV,Sukhorukov VS

    更新日期:2004-11-01 00:00:00

  • Effect of a synthetic indolicidin analogue on lipid peroxidation in thermal burns.

    abstract::Experimental simulation of burn was followed by accumulation of LPO products and suppression of antioxidant enzyme activity in the burn wound. Application of a synthetic analogue of indolicidin led to an increase in MDA and acylhydroperoxide concentrations in the burn wound on experimental day 1. Further application o...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-014-2587-9

    authors: Lazarenko VA,Lyashev YD,Shevchenko NI

    更新日期:2014-08-01 00:00:00

  • Antimutagenic activity of afobazole in various regimens of treatment.

    abstract::The influence of a new 2-mercaptobenzimidazole derivative afobazole on cytogenetic effects of dioxidine and cyclophosphamide was studied by counting chromosome aberrations in bone marrow cells of C57Bl/6 mice. Afobazole (1-100 mg/kg perorally) exhibited antimutagenic activity determined by its antioxidant properties. ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:

    authors: Zhanataev AK,Durnev AD,Seredin SB

    更新日期:2000-11-01 00:00:00

  • Correlation between the results of glucocorticoid therapy and in vitro effect of glucocorticoids on monocytes in asthma.

    abstract::The effects of glucocorticoids on monocyte morphology and function in vitro and the results of high-dose budesonide therapy in patients with non-severe bronchial asthma were analyzed. Before therapy with inhalation glucocorticosteroid (budesonide) characteristics of blood monocytes and the effects of different concent...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1023/a:1025489604819

    authors: Terpigorev SA,Il'chenko VA,Vasilenko IA,Slinchenko OI,Stotskaya TV,Markina TR,Paleev NR

    更新日期:2003-06-01 00:00:00

  • Effect of Ionophores on Activity of Na+,Cl-(HCO 3- )-ATPase.

    abstract::We studied the effects of ionophores on activity of Na+,Cl-(HCO 3- )-ATPase. The most significant effect on the activity of this enzyme was produced by protonophore 2,4-dinitrophenol. The effect of this drug largely depended on the cation and anion composition and pH of the incubation medium and its pH. Activity of Na...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-016-3504-1

    authors: Yurkiv VA,Melikhov VI,Shubin VS

    更新日期:2016-10-01 00:00:00

  • Effect of Annexin V on Development of Apoptosis in Placental Syncytiotrophoblast Nuclei during Exacerbation of Cytomegalovirus Infection in the Third Trimester.

    abstract::During exacerbation of cytomegalovirus infection during pregnancy, cytomegalovirus proteins penetrate across the external membrane of placental villous syncytiotrophoblast and suppress activities of ATPase and Bcl-2 protein. Simultaneous increase in the content of annexin V and caspase 3 leads to structural disturbanc...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-016-3162-3

    authors: Lutsenko MT,Andrievskaya IA

    更新日期:2016-01-01 00:00:00

  • Elevation of seizure threshold after intranasal administration of anti-glutamate antibodies to C57BL/6 mice.

    abstract::The dose-dependent effect of intranasal administration of antibodies to glutamate on acute generalized epileptic activity was studied in C57Bl/6 mice. It was shown that pretreatment with antibodies in doses of 100, 300, and 500 μg/kg 1 h before titration with convulsant pentylenetetrazole had anticonvulsant effects. T...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-013-2140-2

    authors: Karpova MN,Kuznetsova LV,Vetrile LA,Klishina NJ

    更新日期:2013-07-01 00:00:00

  • Antiangiogenic Activity of Alofanib, an Allosteric Inhibitor of Fibroblast Growth Factor Receptor 2.

    abstract::Alofanib is a potential allosteric inhibitor of FGFR2 used in oncology. The inhibitor blocks the extracellular part of the receptor and prevents its binding with the ligand. Alofanib suppressed proliferation of endothelial cells, their migration activity, and ability to form vessellike structures in vitro and signific...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-015-3104-5

    authors: Khochenkov DA,Solomko ES,Peretolchina NM,Ryabaya OO,Stepanova EV

    更新日期:2015-11-01 00:00:00

  • Mechanisms of cervico-vestibular-oculomotor disorders at the early stages of Parkinson's disease.

    abstract::We studied the interaction of the oculomotor, cervical, and vestibular systems using a specially developed technique. A series of two tests were performed on 26 healthy subjects and 42 patients with stages I-II Parkinson's disease receiving and not receiving treatment. In coordinated tests, all amplitude-time characte...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-011-1443-4

    authors: Shvetsov AY,Ivanova EA,Chigalejchik LA,Baziyan BKh

    更新日期:2011-11-01 00:00:00