Effect of carnosine and related compounds on proliferation of cultured rat pheochromocytoma PC-12 cells.

abstract：:Experiments on rats showed that blockade of norepinephrine reuptake in the early reperfusion period after focal myocardial ischemia aggravates myocardial injury and abolishes the protective effect of ischemic preconditioning. ...

journal_title：Bulletin of experimental biology and medicine

authors： Naumenko SE,Latysheva TV,Gilinskii MA

更新日期：2010-12-01 00:00:00

abstract：:Expression of activation antigens increased in patients with gastrointestinal tumors of various clinical courses. The count of CD25+ and CD71+ lymphocytes was high in patients with favorable course of non-progressive tumors. The increase in the expression of activation markers probably reflects adequate functional act...

journal_title：Bulletin of experimental biology and medicine

authors： Oleinik EK,Shibaev MI,Oleinik VM

更新日期：2004-04-01 00:00:00

abstract：:The development of MPTP-induced depressive syndrome in rats was accompanied by activation of prolyl endopeptidase and dipeptidyl peptidase IV in the brain frontal cortex. Prolyl endopeptidase activity in the striatum also increased under these conditions. Our results indicate that proline-specific peptidases in the ta...

journal_title：Bulletin of experimental biology and medicine

authors： Krupina NA,Zolotov NN,Bogdanova NG,Orlova IN,Khlebnikova NN,Kryzhanovskii GN

更新日期：2006-11-01 00:00:00

abstract：:The expression of synaptophysin (vesicular protein) and mGluR5 (metabotropic glutamate receptor) genes was studied 3, 7, and 20 days after cainic acid injury of the dorsal hippocampal area in Wistar rats. The expression of both genes was characteristically reduced in the hippocampus. Twenty days after the exposure the...

journal_title：Bulletin of experimental biology and medicine

authors： Lebedev DS,Arkhipov VI

更新日期：2009-02-01 00:00:00

abstract：:We compared cytotoxic activity of blood mononuclear leukocytes from healthy donors and lymphokine-activated killer cells generated from them towards tumor and normal cells. Lymphokine-activated killer cells exhibited higher (in comparison with blood mononuclear leukocytes) killer activity towards tumor cells. Lymphoki...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova OS,Lebedinskaya OV,Shubina IZh,Gerasimova GK,Karamzin AM,Kiselevskii MV

更新日期：2007-01-01 00:00:00

abstract：:We studied the effects of calcitonin, parathyrin, and Ca(2+) channel antagonist isoptin and agonist Bay-K-8644 on glucose consumption by muscle (diaphragm) and adipose (epididymal) tissues and insulin-stimulated glucose consumption in vivo and in vitro. Calcitonin and parathyrin did not alter glucose consumption; para...

journal_title：Bulletin of experimental biology and medicine

authors： Butakova SS,Nozdrachev AD

更新日期：2009-08-01 00:00:00

abstract：:A new phenomenon (or paradox) consisting in higher statistical stability of samples, for example, tremorograms, in a group of different subjects than in the same subject in unchanged homeostasis. At the same time, it turns out that 15 different subjects are more similar (statistically) to each other than one person to...

journal_title：Bulletin of experimental biology and medicine

authors： Zilov VG,Khadartsev AA,Eskov VM,Ilyashenko LK

更新日期：2019-08-01 00:00:00

abstract：:Chronic administration of neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (30 mg/kg) to C57BL/6 mice caused death of all animals within 7 days. Dipeptide analog of neurotensin active site injected with this neurotoxin protected the mice from death even after 2-week intoxication. When younger mice and lower dos...

journal_title：Bulletin of experimental biology and medicine

authors： Lutsenko VK,Vukolova MN,Kucheryanu VG,Gudasheva TA

更新日期：2003-10-01 00:00:00

abstract：:Exposure of rats with experimental diabetes mellitus to wide-band electromagnetic radiation generated by He-Ne laser and modulated by the pancreas and spleen is informing and phenomenological method prolonging animal life span, normalizing blood glucose level, and promoting regeneration of the pancreas. ...

journal_title：Bulletin of experimental biology and medicine

authors： Garyaev PP,Kokaya AA,Mukhina IV,Leonova-Garyaeva EA,Kokaya NG

更新日期：2007-02-01 00:00:00

abstract：:The rats with neurodegenerative brain disorder induced by administration of a toxic fragment of beta-amyloid demonstrate weakened endothelium-dependent dilation of cerebral vessels, which attested to impaired production of endothelial NO. At the same time, toxic beta-amyloid fragment induced the formation of NO depots...

journal_title：Bulletin of experimental biology and medicine

authors： Mashina SY,Aleksandrin VV,Goryacheva AV,Vlasova MA,Vanin AF,Malyshev IY,Manukhina EB

更新日期：2006-08-01 00:00:00

abstract：:Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level foll...

journal_title：Bulletin of experimental biology and medicine

authors： Kuznetsova NV,Palchikova NA,Selyatitskaya VG,Shkurupiy VA

更新日期：2010-11-01 00:00:00

abstract：:The effects of photostimulation with different colors on α-rhythm amplitude and parameters of variation pulsometry were studied. Green color stimulation modulates human functions: ?-rhythm amplitude increases by 1.06 μV/√Hz (p<0.05) and the index of regulatory systems strain decreases significantly (p<0.05). ...

journal_title：Bulletin of experimental biology and medicine

authors： Osipova MA,Arkov VV,Tonevitsky AG

更新日期：2010-11-01 00:00:00

abstract：:Using rat model of experimental sarcoma M-1 we studied the efficacy of photodynamic therapy with boronated chlorine as a photosensitizer in doses of 1.25, 2.5, 5.0, and 10.0 mg/ kg body weight. Laser irradiation was performed at energy densities of 150, 300 J/cm(2) and power density of 0.25 and 0.42 W/cm(2). Treatment...

journal_title：Bulletin of experimental biology and medicine

authors： Kaplan MA,Ol'shevskaya VA,Osipchuk YS,Nikitina RG,Kalinin VN

更新日期：2014-05-01 00:00:00

abstract：:The combined cytostatic effect of doxorubicin and gestagens progesterone, medroxyprogesterone acetate, mecigestone, and butagest on doxorubicin-resistant and doxorubicin-sensitive human breast cancer MCF-7 cells was studied by the MTT assay. On the 6th day of incubation progesterone, medroxyprogesterone acetate, mecig...

journal_title：Bulletin of experimental biology and medicine

authors： Sergeev PV,Semeikin AV,Fedotcheva TA,Samoilikov RV,Kamernitskii AV,Levina IS,Rzheznikov VM,Grinenko GS,Korystov YN,Ermakova NV,Shaposhnikova VV,Shimanovskii NL

更新日期：2003-11-01 00:00:00

abstract：:We used tests for evaluation of latent period, duration, and accuracy of eyes, head, or hand movements and their coordinated movements. Comparative analysis of these parameters was performed in healthy subjects and in patients with early stages of Parkinson's disease. The pathology data significantly (p<0.05) differed...

journal_title：Bulletin of experimental biology and medicine

authors： Baziyan BKh

更新日期：2012-12-01 00:00:00

abstract：:We analyzed the expression of galectin-1 and galectin-3 in tumor tissue in stomach and colorectal cancer with and without tissue eosinophilia. Low expression of galectin-3 was detected in all patients with malignant gastrointestinal tumors irrespective of the presence of eosinophilia. Low expression of galectin-1 was ...

journal_title：Bulletin of experimental biology and medicine

authors： Kolobovnikova YV,Dmitrieva AI,Yankovich KI,Vasil'eva OA,Purlik IL,Poletika VS,Novitskii VV,Urazova OI

更新日期：2018-06-01 00:00:00

abstract：:We studied the effect of anti-inflammatory cytokine IL-4 (5 μg/kg intraperitoneally) on peripheral blood leukocytes in Wistar rats with various behavioral characteristics during acute emotional stress (1-h immobilization with simultaneous subthreshold electrocutaneous stimulation). IL-4 reduced the differences in bloo...

journal_title：Bulletin of experimental biology and medicine

authors： Pertsov SS,Koplik EV,Kalinichenko LS

更新日期：2015-03-01 00:00:00

abstract：:Trekrezan in a dose of 25 mg/kg normalized the lymphocyte immune status and produced an energy-stabilizing effect, which manifested in decreased levels of lactate, ADP, and AMP and increased content of pyruvate and ATP in blood lymphocytes and lung tissue of rats with experimental acute bronchopneumonia. ...

journal_title：Bulletin of experimental biology and medicine

authors： Zarubina IV,Bolekhan AV,Shabanov PD

更新日期：2006-08-01 00:00:00

abstract：:Electrophysiological parameters of true pacemakers in the sinoatrial node of rat heart were recorded intracellularly using glass microelectrodes. In 11 of 13 experiments acetylcholine in increasing doses did not induce migration of the dominant pacemaker region, while in two cases its minor migration upstream the sinu...

journal_title：Bulletin of experimental biology and medicine

authors： Sutyagin PV,Kalinina EE,Pylaev AS

更新日期：2004-08-01 00:00:00

abstract：:The effect of a 40-day toluene inhalation on learning of young and adult rats was examined in a multi-branched maze. Experimental rats of both age groups needed more time to pass the maze and made more errors than controls. This impairment was observed in young rats immediately after termination of toluene inhalation ...

journal_title：Bulletin of experimental biology and medicine

authors： Bikashvili TZ,Chilachava LR,Gelazonia LK,Japaridze NJ,Zhvania MG,Lordkipanidze TG,Okuneva VG

更新日期：2012-03-01 00:00:00

abstract：:Comparative analysis of proteoglycans in the control and tumor tissue of human mammary gland revealed disorders in the biosynthesis of dermatan sulfate proteoglycans in tumor cells. Using the methods of reverse transcription-PCR and Western blotting for the analysis of decorin expression we showed that these disorders...

journal_title：Bulletin of experimental biology and medicine

authors： Rykova VI,Grigorieva EV,Chernenko AV,Eshenko TY,Dymshits GM

更新日期：2007-09-01 00:00:00

abstract：:The distribution of pacemaker cells and atrial working cardiomyocytes in the anterior right atrial wall was studied using intracellular glass microelectrodes under conditions of short-term culturing. It was shown that the dominant pacemaker region and the functional tail are located in the lateral area of the central ...

journal_title：Bulletin of experimental biology and medicine

authors： Sutyagin PV,Kamkin AG,Gurina OY

更新日期：2009-09-01 00:00:00

abstract：:The antidepressant, psychostimulant, and nootropic effects of a composition of major and trace elements including KCl, RbNO3, magnesium sulfate, and zinc sulfate were studied on the models of behavioural despair (Porsolt test) and conditioned passive avoidance test. The preparation was found to shorten the immobilizat...

journal_title：Bulletin of experimental biology and medicine

authors： Afanasieva OG,Suslov NI,Shilova IV

更新日期：2013-06-01 00:00:00

abstract：:Biopsy specimens from patients with psoriasis treated with antiproliferative drugs (methotrexate, etretinate) were analyzed. Acanthosis and papillomatosis of the epidermis and inflammatory reaction of the derma decreased. A tendency to normalization of epidermocyte ultrastructure with regeneration of tonofilaments and...

journal_title：Bulletin of experimental biology and medicine

authors： Krinitsyna YM,Nepomnyashchikh GI,Aidagulova SV

更新日期：2001-08-01 00:00:00

abstract：:The glucocorticoid status and activities of ALT, AST, and tyrosine aminotransferase in the liver are studied in rats with streptozotocin-induced diabetes mellitus in response to repeated intraperitoneal injections of mifepristone. Diabetic rats develop an increase of the blood corticosterone and liver aminotransferase...

journal_title：Bulletin of experimental biology and medicine

authors： Pal'chikova NA,Selyatitskaya VG,Kuz'minova OI,Pasechnaya KV

更新日期：2018-08-01 00:00:00

abstract：:We studied changes in the blood cytokine profile of rats 3 h, 1 day, and 8 days after acute stress on the model of 24-h immobilization followed by LPS administration (100 μg/kg intraperitoneally). The concentration of proinflammatory cytokines (particularly of IL-1β and TNFα) significantly decreased at the early stage...

journal_title：Bulletin of experimental biology and medicine

authors： Abramova AY,Pertsov SS,Alekseeva IV,Nikenina EV,Kozlov AY,Chekhlov VV,Chukhnina ME

更新日期：2020-04-01 00:00:00

abstract：:We studied electrophysiological parameters and morphological changes in the adrenal glands and spleen of CBA mice feeding a low-choline diet and/or ethanol-containing diet. The polarization coefficient underwent similar changes in the adrenal glands and spleen, which was associated with different contribution of imped...

journal_title：Bulletin of experimental biology and medicine

authors： Tornuev YV,Nepomnyashchikh LM,Koldysheva EV

更新日期：2005-11-01 00:00:00

abstract：:We studied the mechanisms of induction of recombinase activity in peripheral T cells of patients with autoimmune type 1 diabetes mellitus. It was shown that the presence of CD40 on T cell membrane (not typical of these cells) is crucial for this process: expression of recombinase RAG-1 in diabetic patients was detecte...

journal_title：Bulletin of experimental biology and medicine

authors： Kuklina EM,Gorbunova OL,Smirnova EN

更新日期：2012-01-01 00:00:00

abstract：:We studied the effects of neurotensin dipeptide analog Dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) on dopamine metabolism and synthesis in the nucleus accumbens of Wistar rats. Dilept increased the levels of dopamine and its metabolites (homovanillic acid and dioxyphenylalanine) and stimulated dopamine turnove...

journal_title：Bulletin of experimental biology and medicine

authors： Shubenina EV,Kudrin VS,Klodt PM,Narkevich VB,Kuznetsova EA,Gudasheva TA,Ostrovskaya RU

更新日期：2012-09-01 00:00:00

abstract：:Stimulation of lymph circulation and microcirculation and increase in contractile activity of the wall and cusps of valves in lymphatic microvessels are the mechanisms for a therapeutic effect of dimephosphon. These changes improve resorption and transport of tissue and cell metabolites from the interstitial space. ...

journal_title：Bulletin of experimental biology and medicine

authors： Khafiz'yanova RKh,Mukhutdinov DA

更新日期：2005-06-01 00:00:00