Abstract:
:Chronic intranasal administration of fibrillar structures of proinflammatory S100A9 protein impaired passive avoidance learning in old C57Bl/6 mice. Combined treatment with S100A9 fibrils and antibodies to glutamate was followed by an increase in horizontal locomotor activity of animals in the open-field test and did not disturb spatial memory.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Gruden MA,Davydova TV,Fomina VG,Vetrile LA,Morozova-Roche LA,Sewell RDdoi
10.1007/s10517-017-3632-2subject
Has Abstractpub_date
2017-02-01 00:00:00pages
430-432issue
4eissn
0007-4888issn
1573-8221pii
10.1007/s10517-017-3632-2journal_volume
162pub_type
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abstract::The appearance of autoantibodies to neuronal proteins (S100, GFAP, MBP, and NGF) in rat serum was analyzed by ELISA on days 5, 10, 17, 25, and 32 after streptozotocin injection. Simultaneously, blood glucose and insulin autoantibodies were assayed. Serum glucose level increased on the next day after streptozotocin inj...
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abstract::Measurements with extracellular microelectrode technique showed that depolarization of motor nerve terminals in frog cutaneous pectoris muscle with high-potassium solution (40 mM K(+)) increased frequency of miniature end-plate currents. Both fast intracellular calcium chelator BAPTA-AM and slow chelator EGTA-AM equal...
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abstract::The effects of phosphatidylcholine-based phospholipid nanoparticles containing fullerene C60 on Danio rerio fish embryos were studied. Exposure of the embryos with the nanoparticles for 48 h did not lead to appreciable changes in the number of protein bands in SDS-PAGE in comparison with the control (exposure in mediu...
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