Effect of platelet growth factors on proliferation of guinea pig bone marrow and splenic stromal precursor cells and proliferation of cultural descendants from bone marrow precursor cells.

Abstract:

:Elimination of platelets from guinea pig splenocyte suspension (lacking megakaryocytes) with EDTA considerable reduces the efficiency cloning of splenic stromal precursor cells. It means that platelet-derived growth factors are necessary for stromal precursor cells from different organs (bone marrow, thymus, and spleen). The dependence on the platelet growth factors can vary within a wide range in descendants from cultured bone marrow precursor cells (passaged bone marrow fibroblasts at different stages of differentiation.

journal_name

Bull Exp Biol Med

authors

Gorskaya YF,Shuklina EY,Nesterenko VG

doi

10.1023/a:1015847019904

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

272-3

issue

3

eissn

0007-4888

issn

1573-8221

journal_volume

133

pub_type

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