Ultrastructure of neurons in the hypothalamic suprachiasmatic nucleus of rats with different stress reactivity.

abstract：:Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary oral administration of glycine almost completely prevented th...

journal_title：Bulletin of experimental biology and medicine

authors： Selin AA,Lobysheva NV,Vorontsova ON,Tonshin AA,Yaguzhinsky LS,Nartsissov YR

更新日期：2012-05-01 00:00:00

abstract：:We compared the level of transforming growth factor-β1 (TGF-β1) in the tear fluid of 20 patients with high myopia who underwent transepithelial photorefractive keratectomy (T-PRK) in one eye and laser subepithelial keratomileusis (LASEK) in the contralateral eye. Tear fluid samples were collected with scaled microcapi...

journal_title：Bulletin of experimental biology and medicine

authors： Chen JJ,Yang YF,Zeng Y

更新日期：2020-11-01 00:00:00

abstract：:Lyzed epimastigotes of Trypanosoma cruzi clones P209-1, Gamba1, Sp104-1, MASu, Y7/1, MN12, Cl-Brener, 86/2036, Y7/2-1 inhibit the growth of Ehrlich adenocarcinoma in mice. the tumor decreased 1.5-3 times after 12 daily injections of lysates from 15 million epimastigotes. The protective effect progressed after the inje...

journal_title：Bulletin of experimental biology and medicine

authors： Batmonkh Z,Kallinikova VD,Pakhorukova LV,Kravtsov EG,Karpenko LP,Dalin MV

更新日期：2006-10-01 00:00:00

abstract：:The time course of angiotensin-converting enzyme activity in the rat aorta after fractionated exposure to ionizing radiation and the effects of dihydroquercetin and fucoidin on this parameter were studied. Male Wistar rats were exposed to single or repeated (fractionated) X-ray radiation in a dose of 2.5 Gy at 200 kV....

journal_title：Bulletin of experimental biology and medicine

authors： Korystova AF,Kublik LN,Kim YA,Levitman MK,Shaposhnikova VV,Korystov YN

更新日期：2018-07-01 00:00:00

abstract：:Efficiency and mechanisms of action of photodynamic therapy of M-1 sarcoma were studied experimentally on rats using photodithazine, a novel chlorine photosensitizer. The tissue and cellular targets for this agent are vascular wall, plasma membrane of tumor cells, and intracellular structures responsible for prolifera...

journal_title：Bulletin of experimental biology and medicine

authors： Romanko YS,Tsyb AF,Kaplan MA,Popuchiev VV

更新日期：2004-12-01 00:00:00

abstract：:The hypolipidemic effect of Kwai, a preparation based on garlic powder (Allium sativum), depended on the initial content of cholesterol and/or triglycerides. This effect was most pronounced in patients with coronary heart disease with initial cholesterol >7.0 mmol/liter and triglyceride >1.92 mmol/liter. After treatme...

journal_title：Bulletin of experimental biology and medicine

authors： Chernyad'eva IF,Shil'nikova SV,Rogoza AN,Kukharchuk VV

更新日期：2003-05-01 00:00:00

abstract：:We studied the reaction of the microglia of the anterior horns of the rat spinal cord to intraperitoneal administration of bacterial LPS. Immunohistochemical analysis showed that acute systemic inflammation leads to activation of more than half of microglial cells as soon as in 24 h after LPS injection, while the tota...

journal_title：Bulletin of experimental biology and medicine

authors： Kolos EA,Korzhevskii DE

更新日期：2017-08-01 00:00:00

abstract：:Intraperitoneal administration of substance S-1 to male Wistar rats with impaired hearing markedly increased hearing acuity. Substance S-1 had no negative effects on hearing in intact animals. ...

journal_title：Bulletin of experimental biology and medicine

authors： Shestakova EV

更新日期：2002-01-01 00:00:00

abstract：:Cytochemical activity of succinate dehydrogenase and lactate dehydrogenase in blood lymphocytes, activity of hydroperoxides, MDA, and blood plasma antioxidants were studied in experimental animals during immobilization stress after preliminary injection of doxazosin. Preliminary adrenergic receptor blockade prevented ...

journal_title：Bulletin of experimental biology and medicine

authors： Vishnevskii EL,Vishnevskii AE,Shabel'nikova EI,Safronova ON,Dreval AA,Topchieva GV,Sukhorukov VS

更新日期：2004-11-01 00:00:00

abstract：:The degree of oxygen consumption in rats was determined after intraperitoneal injection of morphine in a single dose of 5 mg/kg. Some animals were injected with morphine and perorally received morphine or antibodies to mu-opiate receptors in ultralow doses obtained by the technology of potentiation. Potentiated substa...

journal_title：Bulletin of experimental biology and medicine

authors： Pavlov IF,Epstein OI

更新日期：2003-01-01 00:00:00

abstract：:Autooxidation of low-density lipoproteins during incubation at 37 degrees C was accompanied by accumulation of LPO products, decrease in UV autofluorescence (FUV), and increase in autofluorescence in the visible band (FVIS). The degree of low-density lipoprotein modification was estimated by calculating the FVIS/FUV r...

journal_title：Bulletin of experimental biology and medicine

authors： Aidyraliev RK,Azizova OA,Vakhrusheva TV,Lopukhin YM,Mirrakhimov MM

更新日期：2006-10-01 00:00:00

abstract：:The features of B16 melanoma progression in male C57BL/6 mice with initially high and low resistance to hypoxia were studied. To assess the resistance to hypoxia, the mice were placed in a low-pressure chamber at a simulated altitude of 10,000 m. One month after testing, B16 melanoma was inoculated to high- and low-re...

journal_title：Bulletin of experimental biology and medicine

authors： Fridman IA,Ponomarenko EA,Makarova OV,Postovalova EA,Zolotova NA,Khochanskiy DN,Mkhitarov VA,Tsvetkov IS,Kosyreva AM

更新日期：2020-01-01 00:00:00

abstract：:Penetration of pegylated (enveloped in polyethylene glycol) gold nanoparticles 5 and 30 nm in diameter through the placental barrier was studied in pregnant rats injected intravenously with these particles in a dose of about 0.8 mg Au/kg on day 10 of gestation. The particles were visualized in tissues by silver nitrat...

journal_title：Bulletin of experimental biology and medicine

authors： Tsyganova NA,Khairullin RM,Terentyuk GS,Khlebtsov BN,Bogatyrev VA,Dykman LA,Erykov SN,Khlebtsov NG

更新日期：2014-07-01 00:00:00

abstract：:The number of CD3(+)CD56-HLA-G(+) cells in the peripheral blood of breast cancer patients was shown to increase by 2 times. Our results and published data suggest that the increase in the relative content of CD3(+)CD56-HLA-G(+) cells in the circulating blood in breast cancer contributes to tumor development due to sup...

journal_title：Bulletin of experimental biology and medicine

authors： Ostapchuk EO,Perfi L'eva YV,Talaeva ShZh,Omarbaeva NA,Belyaev NN

更新日期：2015-09-01 00:00:00

abstract：:Burn trauma increased blood chemiluminescence, while lipopolysaccharide in a dose of 1 mg/kg potentiated this effect, activated LPO, and decreased plasma antioxidant activity. In erythrocytes, superoxide dismutase activity increased, while activity of peroxide-utilizing enzymes decreased. Myeloperoxidase content incre...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhal'chik EV,Titkova SM,Anurov MV,Ettinger AP,Korkina LG

更新日期：2006-06-01 00:00:00

abstract：:Comparative analysis of the state of the thymus, activity of cell component of the immune system, and open field behavior of Wistar and OXYS rats showed early involution of the thymus in OXYS rats. By morphological picture this involution corresponded to accidental involution and was paralleled by low level of delayed...

journal_title：Bulletin of experimental biology and medicine

authors： Markova EV,Obukhova LA,Kolosova NG

更新日期：2003-12-01 00:00:00

abstract：:Stimulation of the labyrinth in rabbits and guinea pigs with ascending (cathode) or descending direct current (anode) induced deviation and nystagmus of the eyes, head turn and tilt, and other reactions. Anodization of both labyrinths was followed by the disappearance of reflexes, suppression of vestibular reactions t...

journal_title：Bulletin of experimental biology and medicine

authors： Gorgiladze GI

更新日期：2004-12-01 00:00:00

abstract：:Apoptosis of blood neutrophils from healthy donors was studied under conditions of cell culturing with different concentrations of H(2)O(2), selective NO synthase inhibitor, and inductor of NO synthesis (L-arginine). In vitro incubation of neutrophilic leukocytes with 5 mM H(2)O(2) led to activation of the apoptotic p...

journal_title：Bulletin of experimental biology and medicine

authors： Stepovaya YA,Zhavoronok TV,Starikov YV,Bychkov VA,Chasovskih NY,Starikova YG,Petina GV,Novitsky VV,Ryazantseva NV

更新日期：2008-12-01 00:00:00

abstract：:In acute experiments on anesthetized cats activity of sensomotor cortical units was recorded during low-frequency stimulation of the head of the caudate nucleus. Amphetamine (1 mg/kg), although not significantly affecting the spontaneous firing rate, increased the number of spontaneously active cortical units. Meanwhi...

journal_title：Bulletin of experimental biology and medicine

authors： Arushanyan EB,Belozertsev YA,Aivazov KG

更新日期：1975-01-01 00:00:00

abstract：:Analysis of contribution of sympathetic and parasympathetic systems into heart rate variability carried out using atenolol and atropine showed that August rats are characterized by enhanced tone of the sympathetic system and reduced tone of the parasympathetic system compared to Wistar rats. Reduced tone of the parasy...

journal_title：Bulletin of experimental biology and medicine

authors： Kirillina TN,Usacheva MA,Belkina LM

更新日期：2006-10-01 00:00:00

abstract：:We measured the content of glutathione and activity of glutathione-metabolizing and antioxidant enzymes superoxide dismutase and catalase in samples obtained from 52 patients with malignant lung tumors and 20 patients with benign lung tumors. The content of glutathione and activity of glutathione-metabolizing enzymes ...

journal_title：Bulletin of experimental biology and medicine

authors： Korotkina RN,Matskevich GN,Devlikanova ASh,Vishnevskii AA,Kunitsyn AG,Karelin AA

更新日期：2002-06-01 00:00:00

abstract：:Using an integral qualitative and quantitative approach to the studies of initiation of the biological material crystallogenesis, we showed in experiments with normal human saliva that the external characteristics of biological fluid (pH, osmolality, and environmental temperature) determine the results of crystallizat...

journal_title：Bulletin of experimental biology and medicine

authors： Martusevich AK,Kamakin NF

更新日期：2007-03-01 00:00:00

abstract：:We studied the effects of cholesterol, its oxidized derivatives mevalonate, and nuclear receptor agonists LXR, RXR, and FXR on the production of transforming growth factor-beta1 (TGF- beta1) by macrophages. After recruiting of macrophage monocytes into the focus of inflammation, the production of TGF-beta1 increased b...

journal_title：Bulletin of experimental biology and medicine

authors： Schwartz YSh,Khoshchenko OM,Dushkin MI,Feofanova NA

更新日期：2009-09-01 00:00:00

abstract：:Experiments on rats showed that activation of the peripheral ion channel TRPM8 with menthol and rapid cooling (decrease in core temperature by 3°C) led to 1.5-fold activation of the expression of TRPV3 ion channel gene in the posterior hypothalamus, but had no effect on the expression of this gene in the anterior hypo...

journal_title：Bulletin of experimental biology and medicine

authors： Kozyreva TV,Evtushenko AA,Voronova IP,Khramova GM,Kozaruk VP

更新日期：2018-12-01 00:00:00

abstract：:We studied the effect of Herceptin therapy on the population composition of lymphocytes and percentage of CD4+CD25+ cells (regulatory T cells) in breast cancer patients. Herceptin treatment decreased the number of "professional" T suppressors (CD4+CD25+ cells and regulatory T cells) in the peripheral blood. ...

journal_title：Bulletin of experimental biology and medicine

authors： Slavina EG,Chertkova AI,Zabotina TN,Gan'shina IP,Lichinitser MR

更新日期：2006-03-01 00:00:00

abstract：:Here we present the results of histochemical detection of 3β-hydroxysteroid dehydrogenase in neurons of the neocortex, cerebellum, and brainstem. The positive reaction was observed in a low number of neocortical, midbrain, and pontine neurons. The maximum number of positive neurons was detected in the cerebellar corte...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva VM

更新日期：2012-01-01 00:00:00

abstract：:Multivariate analysis was used to examine the morphology of mixed saliva crystals in 55 healthy men and the patients with suspected malignant prostate gland diseases. The established changes in the shape of dendritic crystals in the saliva from prostate-problematic patients were corroborated by the cluster and discrim...

journal_title：Bulletin of experimental biology and medicine

authors： Denisov AB,Pushkar' DY,Denisov SA

更新日期：2006-08-01 00:00:00

abstract：:We compared cytotoxic activity of blood mononuclear leukocytes from healthy donors and lymphokine-activated killer cells generated from them towards tumor and normal cells. Lymphokine-activated killer cells exhibited higher (in comparison with blood mononuclear leukocytes) killer activity towards tumor cells. Lymphoki...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova OS,Lebedinskaya OV,Shubina IZh,Gerasimova GK,Karamzin AM,Kiselevskii MV

更新日期：2007-01-01 00:00:00

abstract：:Transplantation of human bone marrow mesenchymal stem cells is considered as a promising therapeutic approach to the therapy of many diseases. However, the problem of possible alterations of the properties of mesenchymal stem cells during their expansion in in vitro cultures before transplantation is not solved. In ou...

journal_title：Bulletin of experimental biology and medicine

authors： Grigorian AS,Kruglyakov PV,Taminkina UA,Efimova OA,Pendina AA,Voskresenskaya AV,Kuznetsova TV,Polyntsev DG

更新日期：2010-12-01 00:00:00

abstract：:The expression of mRNA of proteins involved in the transformations of cytostatics (cytochrome P-450 1A1 and 1B1 isoforms) and genes encoding proteins participating in their regulation (Ah receptor, AHRR and ARNT) in intestinal tumors and intact portions of the intestine were studied. The expression of cytochrome P-450...

journal_title：Bulletin of experimental biology and medicine

authors： Evteev VA,Barsukov JA,Aliev VI,Kobliakov VA

更新日期：2008-08-01 00:00:00