Activation of Microglyocytes in the Anterior Horns of Rat Spinal Cord after Administration of Bacterial Lipopolysaccharide.

abstract：:Changes in the diurnal light cycle affect the morphofunctional state of the pineal gland. The volume of the nucleus, Golgi apparatus, and mitochondria in pinealocytes decreases after 45-day exposure to bright light. After 90 days, the degree of nuclear polymorphism increased, the specific volume of the Golgi apparatus...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimov AV,Logvinov SV,Kostyuchenko VP

更新日期：2010-12-01 00:00:00

abstract：:Effects of low-intensity microwave radiation with bioactive frequency were studied in rats with transplanted sarcoma 45. After exposure to microwave radiation in the regimen of activation therapy, the antitumor effect was observed in 50% animals (marked inhibition of tumor growth or its partial regression). Light and ...

journal_title：Bulletin of experimental biology and medicine

authors： Gudzkova TN,Zhukova GV,Garkavi LH,Sukhanova MI,Evstratova OF,Barteneva TA

更新日期：2011-03-01 00:00:00

abstract：:Pronounced antitumor effect of Thymalin in doses lower than the therapeutic doses was shown in experiments on albino outbred male rats with transplanted sarcoma 45. Tumor growth arrest and its regression were observed in more than half of animals and in other cases, the growth was suppressed by 78%. Microstructural ch...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova GV,Schikhlyarova AI,Barteneva TA,Shevchenko AN,Zakharyuta FM

更新日期：2018-05-01 00:00:00

abstract：:We studied secretory activity of adrenal zona fasciculata cells in pubertal rats exposed to low doses of endocrine disrupter DDT during prenatal and postnatal periods and only during postnatal period. In exposed animals, circulatory disturbances leading to degeneration and necrosis of cells as well as regeneration foc...

journal_title：Bulletin of experimental biology and medicine

authors： Yaglova NV,Tsomartova DA,Obernikhin SS,Nazimova SV,Yaglov VV

更新日期：2018-12-01 00:00:00

abstract：:Morphological and histoenzymatic changes in cells of the spinal cord and spinal ganglia after epidural injection of a combination of prosidol with clonidine were studied on dogs. No pathological structural and metabolic changes in the nervous tissue were found after combined treatment with the test drugs. Higher activ...

journal_title：Bulletin of experimental biology and medicine

authors： Volchkov VA,Strashnov VI,Tomson VV,Boikova NV,Zaitsev AA

更新日期：2001-09-01 00:00:00

abstract：:Plasma cytokine concentration in patients with Parkinson's disease and mutation in GBA gene, in patients with sporadic Parkinson's disease, and in healthy volunteers were measured by ELISA and multiplex analysis. In patients with Parkinson's disease and mutation in GBA gene, elevated plasma concentrations of IL-1β and...

journal_title：Bulletin of experimental biology and medicine

authors： Miliukhina IV,Usenko TS,Senkevich KA,Nikolaev MA,Timofeeva AA,Agapova EA,Semenov AV,Lubimova NE,Totolyan AA,Pchelina SN

更新日期：2020-02-01 00:00:00

abstract：:We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Naumova LA,Osipova ON,Klinnikova MG

更新日期：2019-04-01 00:00:00

abstract：:Incomplete varying obstruction of the urinary tract was reproduced by injecting artificial stomatological material into the rat bladder. Inflammatory changes and nephrosclerosis were detected in the renal tissue on days 14 and 21 of the experiment. Urinary concentration of total protein and activity of γ-glutamylamino...

journal_title：Bulletin of experimental biology and medicine

authors： Sosnin DA,Novochadov VV,Ostrovsky OV

更新日期：2013-04-01 00:00:00

abstract：:We studied properties of cloned BACE mRNA (beta-site of the enzyme cleaving amyloid precursor protein) and evaluated the possibility of using this clone for identification and/or prediction of neurodegenerative disorders associated with cholinergic deficiency. Wistar rats subjected to immunohistochemical destruction o...

journal_title：Bulletin of experimental biology and medicine

authors： Lushchekina EA,Bigl M,Apelt J,Lange-Dohna C,Rossner S,Schliebs R

更新日期：2002-09-01 00:00:00

abstract：:Angiogenic action of compound GK-2, a dimeric dipeptide mimetic of loop 4 of nerve growth factor (NGF), was studied in in vitro and in vivo experiments. Experiments on human endothelial cell culture HUVEC showed that compound GK-2 significantly (p<0.05) stimulated the initial stage of angiogenesis, and its angiogenic ...

journal_title：Bulletin of experimental biology and medicine

authors： Kryzhanovskii SA,Antipova TA,Tsorin IB,Pekeldina ES,Stolyaruk VN,Nikolaev SV,Sorokina AV,Gudasheva TA,Seredenin SB

更新日期：2016-08-01 00:00:00

abstract：:We studied the effect of vasopressin analogue desglycinamide-arginine-vasopressin on changes in platelet hemostasis produced by intragastric administration of Ticlid or clopidogrel (inhibitors of ADP-induced platelet aggregation). Intranasal administration of the peptide under conditions of hemorrhagic diathesis produ...

journal_title：Bulletin of experimental biology and medicine

authors： Golubeva MG,Grigoreva ME,Smirnova MP

更新日期：2005-08-01 00:00:00

abstract：:The effect of serotoninotropic substances with positive and negative effects on serum concentrations of thyrotropic hormone, total triiodothyronine, and total thyroxin was studied in old male rats. Chronic treatment with L-tryptophan and citalopram reduced serum level of total thyroxin in old intact animals and serum ...

journal_title：Bulletin of experimental biology and medicine

authors： Masalova OO,Sapronov NS

更新日期：2009-11-01 00:00:00

abstract：:Transcription profiles of genes of local immune response were determined in the vagina of women with bacterial vaginosis, aerobic vaginitis, and vulvovaginal candidosis for detection of the most specific immune markers for these vaginal infections. Laboratory diagnosis of the vaginal infections was performed microscop...

journal_title：Bulletin of experimental biology and medicine

authors： Budilovskaya OV,Shipitsina EV,Spasibova EV,Pereverzeva NA,Vorob'eva NE,Tsypurdeeva ND,Grigoryev AN,Savicheva AM

更新日期：2020-03-01 00:00:00

abstract：:Morphometric analysis of structural and functional changes in the human mesenteric lymph nodes during aging revealed the development of fibrous connective tissue, fragmentation of the lymphoid parenchyma, the absence of follicles with germinal centers, and a decrease in the level of lymphocyte proliferation, which was...

journal_title：Bulletin of experimental biology and medicine

authors： Erofeeva LM,Mnikhovich MV

更新日期：2020-03-01 00:00:00

abstract：:A course of ascovertin therapy reduced manifestations of perifocal inflammation and atresia of growing follicles, corrected vascular disorders and changes in the tissue volume ratios outside the necrotic zone after monopolar coagulation of the ovaries in rats. The drug prevented the increase in blood viscosity, erythr...

journal_title：Bulletin of experimental biology and medicine

authors： Logvinov SV,Plotnikov MB,Tikhonovskaya OA,Bukharina IY,Maslov MY,Petrova MS

更新日期：2003-04-01 00:00:00

abstract：:Spontaneous platelet aggregation was evaluated in patients with acute coronary syndrome on days 1, 3-5, and 8-12 of the disease. On day 1, aggregation was analyzed after aspirin, but before clopidogrel administration; during other periods after both antiaggregants. The mean levels of spontaneous aggregation after anti...

journal_title：Bulletin of experimental biology and medicine

authors： Mazurov AV,Khaspekova SG,Yakushkin VV,Khachikyan MV,Zyuryaev IT,Ruda MY

更新日期：2013-05-01 00:00:00

abstract：:The combined cytostatic effect of doxorubicin and gestagens progesterone, medroxyprogesterone acetate, mecigestone, and butagest on doxorubicin-resistant and doxorubicin-sensitive human breast cancer MCF-7 cells was studied by the MTT assay. On the 6th day of incubation progesterone, medroxyprogesterone acetate, mecig...

journal_title：Bulletin of experimental biology and medicine

authors： Sergeev PV,Semeikin AV,Fedotcheva TA,Samoilikov RV,Kamernitskii AV,Levina IS,Rzheznikov VM,Grinenko GS,Korystov YN,Ermakova NV,Shaposhnikova VV,Shimanovskii NL

更新日期：2003-11-01 00:00:00

abstract：:At the early stages of development (3 months), transplants from bone marrow donors subjected to single in vivo stimulation (curettage, administration of BMP-2 or antigenic complex of S. typhimurium) 1 day before transplantation were characterized by significantly elevated content of nucleated cells (by 1.4, 1.9 and 2....

journal_title：Bulletin of experimental biology and medicine

authors： Gorskaya YF,Nesterenko VG

更新日期：2017-05-01 00:00:00

abstract：:Parameters of cardiac activity after administration of the cholinesterase inhibitor physostigmine were analyzed in newborn rats and on day 16 of postnatal development. The type of cardiovascular response to acetylcholine excess in newborns and 16-day-old rats were similar, but they significantly differed by the magnit...

journal_title：Bulletin of experimental biology and medicine

authors： Sizonov VА,Dmitrieva LE

更新日期：2018-05-01 00:00:00

abstract：:Histaminergic contractile reactions of smooth muscles in rabbit lobar pulmonary arteries were studied using in vitro mechanographic technique. Histamine via activation of H-receptors induced a dose-dependent constriction of smooth muscle segments, while endothelium inhibited histamine-induced contractile reactions. Hi...

journal_title：Bulletin of experimental biology and medicine

authors： Kapilevich LV,Anfinogenova YD,Nosarev AV,Baskakov MB,Kovalev IV,D'yakova EY,Medvedev MA

更新日期：2001-08-01 00:00:00

abstract：:Total antioxidant activity of the serum in patients with liver pathology was assessed by two chemiluminescent methods based on different models of free radical oxidation: Hb-H2O2-luminol and ABAP-luminol. Comparative analysis showed a significant, but not high correlation of the results (r=0.798), which can be explain...

journal_title：Bulletin of experimental biology and medicine

authors： Titov VN,Sazhina NN

更新日期：2014-12-01 00:00:00

abstract：:We compared the level of transforming growth factor-β1 (TGF-β1) in the tear fluid of 20 patients with high myopia who underwent transepithelial photorefractive keratectomy (T-PRK) in one eye and laser subepithelial keratomileusis (LASEK) in the contralateral eye. Tear fluid samples were collected with scaled microcapi...

journal_title：Bulletin of experimental biology and medicine

authors： Chen JJ,Yang YF,Zeng Y

更新日期：2020-11-01 00:00:00

abstract：:We studied cardiac pumping function in the offspring of rats subjected to swimming exercise and the offspring of untrained rats. The rat pups were adapted for swimming with stepwise increasing load from day 21 to 70 life. At the age of 21 and 70 days, offspring of trained rats showed lower HR and significantly higher ...

journal_title：Bulletin of experimental biology and medicine

authors： Valeev AM,Abzalov NI,Abzalov RA,Nigmatullina RR,Abzalov RR,Nikitin AS

更新日期：2012-07-01 00:00:00

abstract：:Experiments on rats showed that high-intensity light exposure (6000 lux, 6 h) caused focal injuries in the retina. The most sensitive structures were neurosensory cells, pigmented epithelium, radial gliocytes, and choroid capillaries. Injection of ascovertin led to disappearance of foci of injuries, limited blood supp...

journal_title：Bulletin of experimental biology and medicine

authors： Logvinov SV,Plotnikov MB,Varakuta EY,Zhdankina AA,Potapov AV,Mikhulya EP

更新日期：2005-11-01 00:00:00

abstract：:Intranigral administration of glutamate to rats with parkinsonian syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine augmented the development of parkinsonian symptoms (oligokinesia and muscular rigidity), but did not affect motor activity of intact animals. Memantine administered intraperitoneally in pa...

journal_title：Bulletin of experimental biology and medicine

authors： Kucheryanu VG,Kryzhanovskii GN

更新日期：2000-07-01 00:00:00

abstract：:No appreciable disorders of cellular immunity were detected in patients with glandular cystic endometrial hyperplasia. Atypical endometrial hyperplasia was associated with quantitative changes in T lymphocytes and their subpopulations, decreased level of lymphocytes carrying activation antigens, and increased count of...

journal_title：Bulletin of experimental biology and medicine

authors： Lysenko ON,Strizhova NV,Kholodova ZhL

更新日期：2003-01-01 00:00:00

abstract：:Function of sarcoplasmic reticulum was studied in rat papillary muscles treated with amiodarone. An extra stimulus (0.5 Hz) was delivered to the muscle 0.225 sec after application of a regular stimulus. Postextrasystolic potentiation was evaluated in control myocardial samples and samples treated with amiodarone. The ...

journal_title：Bulletin of experimental biology and medicine

authors： Afanas'ev SA,Lukavskaya IA,Kandinskii ML,Medvedev MA

更新日期：2002-03-01 00:00:00

abstract：:Enzyme immunoassays showed significantly elevated content of matrix metalloproteinase 7 and type 1 tissue inhibitor of metalloproteinases in tumors compared to adjacent histologically unchanged mucosa of patients with colorectal cancer; the levels of metalloproteinase 9 and type 4 tissue inhibitor of metalloproteinase...

journal_title：Bulletin of experimental biology and medicine

authors： Gershtein ES,Korotkova EA,Shcherbakov AM,Prorokov VV,Golovkov DA,Kushlinskii NE

更新日期：2007-04-01 00:00:00

abstract：:The mechanisms of therapeutic resistance of human glioblastoma multiforme are analyzed. The authors make an attempt at systematization and scientific theoretical validation of new approaches to creation of biomedical cellular preparations, based on the oncoproteomic technologies, for personified therapy of the glial t...

journal_title：Bulletin of experimental biology and medicine

authors： Bryukhovetskii IS,Bryukhovetskii AS,Khotimchenko YS

更新日期：2015-04-01 00:00:00

abstract：:Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary oral administration of glycine almost completely prevented th...

journal_title：Bulletin of experimental biology and medicine

authors： Selin AA,Lobysheva NV,Vorontsova ON,Tonshin AA,Yaguzhinsky LS,Nartsissov YR

更新日期：2012-05-01 00:00:00