Abstract:
:Enzyme immunoassays showed significantly elevated content of matrix metalloproteinase 7 and type 1 tissue inhibitor of metalloproteinases in tumors compared to adjacent histologically unchanged mucosa of patients with colorectal cancer; the levels of metalloproteinase 9 and type 4 tissue inhibitor of metalloproteinases were virtually the same in the tumors and mucosa. Plasma concentrations of the studied proteins did not correlate with their levels in the tumor, did not surpass the normal, and did not decease after removal of the primary tumor in the majority of patients.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Gershtein ES,Korotkova EA,Shcherbakov AM,Prorokov VV,Golovkov DA,Kushlinskii NEdoi
10.1007/s10517-007-0156-1subject
Has Abstractpub_date
2007-04-01 00:00:00pages
459-62issue
4eissn
0007-4888issn
1573-8221journal_volume
143pub_type
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