Interaction of human apolipoprotein A-I with rsCD4 receptor.

abstract：:We studied the peculiarities of oxidative and substrate phosphorylation in isolated cardiomyocytes and myocardial mitochondria in 2- and 15-month-old rats. It was shown that age factor reduces the degree of oxidation and phosphorylation coupling both in cardiomyocytes and in mitochondria, which was associated with the...

journal_title：Bulletin of experimental biology and medicine

authors： Tsapko LP,Afanas'ev SA

更新日期：2019-08-01 00:00:00

abstract：:Solid-phase ELISA revealed increased content of macrophage-granulocyte colony-stimulating factor and basic fibroblast growth factor in the serum of hyperlipoproteinemic patients. ...

journal_title：Bulletin of experimental biology and medicine

authors： Saburova OS,Tvorogova MG,Soboleva EL

更新日期：2003-02-01 00:00:00

abstract：:The effect of panavir on Parkinson's syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine was studied in C57Bl/6 mice and outbred albino rats. Two injections of panavir significantly reduced the severity of oligokinesia and autonomic manifestations of experimentally induced Parkinson's syndrome. ...

journal_title：Bulletin of experimental biology and medicine

authors： Kalinina TS,Nerobkova LN,Voronina TA,Stovbun SV,Litvin AA,Sergienko VI

更新日期：2005-07-01 00:00:00

abstract：:We studied the interaction between the sympathetic and parasympathetic parts of the autonomic nervous system in the regulation of smooth muscles in the femoral artery and trachea. It was shown that this regulation involves ganglionic serotoninergic neurons transmitting excitation to 5-HT, receptors in the effector tis...

journal_title：Bulletin of experimental biology and medicine

authors： Lazebnik LB,Lychkova AE

更新日期：2006-01-01 00:00:00

abstract：:Study was performed by counting cells with chromosomal aberrations in C57Bl/6 mice. Bark dry extract was given perorally in doses of 50, 150, 450, and 1500 mg/kg. Mutagens dioxidine and cyclophosphamide were injected intraperitoneally in doses of 200 and 20 mg/kg, respectively. Bark dry extract in doses of 150 and 150...

journal_title：Bulletin of experimental biology and medicine

authors： Zhanataev AK,Presnova GA,Chistyakov AN,Durnev AD

更新日期：2004-11-01 00:00:00

abstract：:The effect of a 40-day toluene inhalation on learning of young and adult rats was examined in a multi-branched maze. Experimental rats of both age groups needed more time to pass the maze and made more errors than controls. This impairment was observed in young rats immediately after termination of toluene inhalation ...

journal_title：Bulletin of experimental biology and medicine

authors： Bikashvili TZ,Chilachava LR,Gelazonia LK,Japaridze NJ,Zhvania MG,Lordkipanidze TG,Okuneva VG

更新日期：2012-03-01 00:00:00

abstract：:We studied sterility and toxicity of vaccine LS1 containing aberrant gangliosides isolated from brain bioptates of 48 patients with gliomas of different malignancy and covalently bound to keyhole limpet hemocyanin. The vaccine was safe. This preparation produced no side effects in experimental animals. Our findings su...

journal_title：Bulletin of experimental biology and medicine

authors： Lombardi V,Shnaar R,Minev B,Misasi R,Gitstsi Kh,Sorice M,Troncone A

更新日期：2002-10-01 00:00:00

abstract：:Experiments on outbred albino rats showed that subacute poisoning with tetrachloromethane in a total dose of 1.0 LD50 appreciably decreased blood concentrations of cytokines (IFN-gamma, IL-2, IL-4, IL-6, IL-10), reduced the IFN-gamma/IL-4 ratio in comparison with the control, and suppressed the immune reactions, which...

journal_title：Bulletin of experimental biology and medicine

authors： Zabrodskii PF,Kirichuk VF,Lim VG,Balashov SV,Svistunov AA

更新日期：2009-01-01 00:00:00

abstract：:Influenza virus hemagglutinins are surface proteins responsible for fusion of the viral and cellular membranes. Their capacity to mediate membrane fusion (fusogenic activity) is studied by various methods, including the syncytium formation and pseudovirus transduction methods. We constructed plasmids coding for genes ...

journal_title：Bulletin of experimental biology and medicine

authors： Kononova AA,Cheresiz SV,Chechushkov AV,Razumova YV,Pokrovskii AG

更新日期：2017-11-01 00:00:00

abstract：:Isolation and identification of rat brain protein regulated by serotonin-modulated protein SMP-69 is described. Intracerebral administration of anti-SMP-69 antibodies activates cerebral cortex cell genome and increases the content of electropheretic fraction 28. Intracerebral administration of isolated and purified pr...

journal_title：Bulletin of experimental biology and medicine

authors： Mekhtiev AA

更新日期：2000-08-01 00:00:00

abstract：:Applications of cold and warm activated cellular immunity and orientation and exploratory behavior in mice. Application of cold increased the number of turns to the left in the open field, muscle force, and activity of the food instinct, and caused an increase in the total count of peripheral blood leukocytes. Warm ap...

journal_title：Bulletin of experimental biology and medicine

authors： Kalyonova LF,Novikova MA

更新日期：2013-04-01 00:00:00

abstract：:Number and size of aggregated lymphoid nodules in the small intestine of mice exposed to radiation using a γ-irradiation unit GOBO-60 with 137Cs source were measured using the methods of visual microscopy and morphometry. Morphological status of the nodules was estimated on days 4, 28, 60, and 90 after the exposure. S...

journal_title：Bulletin of experimental biology and medicine

authors： Klochkova SV,Kvaratskheliya AG,Alekseeva NT,Nikityuk DB

更新日期：2017-12-01 00:00:00

abstract：:Peroral administration of alpha-tocopherol in a daily dose of 150 mg/kg for 1, 4, 8, and 12 days leads to induction of cytochromes P450 1A in male rats. Activity of CYP1A1 and CYP1A2 increased most significantly one day after alpha-tocopherol administration (by 2.6 and 2.7 times, respectively). CYP1A1 was immunohistoc...

journal_title：Bulletin of experimental biology and medicine

authors： Sidorova YA,Grishanova AY,Lyakhovich VV

更新日期：2004-09-01 00:00:00

abstract：:We designed a new complex drug with antiallergic effect containing, in addition to the main component loratadine, a phytocomplex for an extra therapeutic effect. A collection of plants with sedative activity is chosen and the optimal agent for extraction of bioactive compounds (40% ethanol) and optimal degree of plant...

journal_title：Bulletin of experimental biology and medicine

authors： Kulikovskii VF,Zhilyakova ET,Novikov OO,Pisarev DI,Prokushchenko NV,Ivanova LL

更新日期：2017-10-01 00:00:00

abstract：:Silicon crystal 2-5 nm nanoparticles in the form of 1-5-μ granules in water suspension were injected intraperitoneally in a single dose to male F(1)(CBA×C57Bl/6) mice or to outbred albino rats on days 1, 7, and 14 of gestation. Silicon crystal nanoparticles in doses of 5, 25, and 50 mg/kg exhibited no cytogenetic acti...

journal_title：Bulletin of experimental biology and medicine

authors： Durnev AD,Solomina AS,Daugel-Dauge NO,Zhanataev AK,Shreder ED,Nemova EP,Shreder OV,Veligura VA,Osminkina LA,Timoshenko VY,Seredenin SB

更新日期：2010-10-01 00:00:00

abstract：:Phenibut and its derivatives normalized cellular (index of delayed-type hypersensitivity reaction) and humoral (antierythrocyte antibody titer) immunity and the lymphoproliferative processes in immunocompetent organs of animals with cyclophosphamide-induced immunosuppression. This indicates pronounced immunocorrective...

journal_title：Bulletin of experimental biology and medicine

authors： Tyurenkov IN,Samotrueva MA

更新日期：2009-05-01 00:00:00

abstract：:We studied the effects of dipeptidyl peptidase 4 (DPP4) inhibitor linagliptin on the expression of apoptosis regulator proteins Bcl-2 and Bad in the liver of db/db mice with genetically determined obesity and type 2 diabetes mellitus. The mice received daily linagliptin or saline (placebo) by gavage from week 10 to we...

journal_title：Bulletin of experimental biology and medicine

authors： Michurina SV,Cherepanova MA,Ishchenko IY,Arkhipov SA,Klimontov VV,Zav'yalov EL

更新日期：2019-06-01 00:00:00

abstract：:Using rat model of spinal cord contusion injury at TVIII, we compared the effectiveness of immediate single transplantation of human mononuclear umbilical cord blood cells transfected with pBud-VEGF-FGF2 plasmid and immediate direct injection of the same plasmid into the lesion area. The results suggest that the deliv...

journal_title：Bulletin of experimental biology and medicine

authors： Shaymardanova GF,Mukhamedshina YO,Salafutdinov II,Rizvanov AA,Chelyshev YA

更新日期：2013-02-01 00:00:00

abstract：:We studied competitive activities of 16 alpha,17 alpha-cyclohexano-5 alpha- and 5 beta-dihydroprogesterone in replacing(3)H-progesterone and(3)H-16 alpha,17 alpha-cyclohexano-6 alpha-methylprogesterone from protein complexes. Direct binding of(3)H-5-reduced derivatives with proteins of soluble fractions from rat and r...

journal_title：Bulletin of experimental biology and medicine

authors： Smirnov AN,Pokrovskaya EV,Levina IS,Kulikova LE,Kamernitskii AV,Shevchenko VP

更新日期：2001-03-01 00:00:00

abstract：:Ultralow doses of antibodies to histamine in produced an antiproliferative effect on experimental animals with inflammation. Analgesic activity of antibodies to histamine was revealed on the model of acetic acid-induced writhing. ...

journal_title：Bulletin of experimental biology and medicine

authors： Krylova SG,Razina TG,Zueva EP,Amosova EN,Shilova NV,Dugina YL,Epstein OI

更新日期：2003-01-01 00:00:00

abstract：:Metabolic processes in the brain cortex of albino rats with prenatal and postnatal alcohol intoxication were studied by the method of electron paramagnetic resonance. Accumulation of superoxide radical-generating agents, inactivation of superoxide dismutase, and increase in nitric oxide concentration were detected. Ac...

journal_title：Bulletin of experimental biology and medicine

authors： Museridze DP,Sanikidze TV,Svanidze IK

更新日期：2006-09-01 00:00:00

abstract：:Intranigral administration of glutamate to rats with parkinsonian syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine augmented the development of parkinsonian symptoms (oligokinesia and muscular rigidity), but did not affect motor activity of intact animals. Memantine administered intraperitoneally in pa...

journal_title：Bulletin of experimental biology and medicine

authors： Kucheryanu VG,Kryzhanovskii GN

更新日期：2000-07-01 00:00:00

abstract：:We studied the effect of gold nanospheres coated with components of autologous blood plasma on ADP-induced platelet aggregation. Gold nanoparticles in the chosen concentration range (5-40 μM) and particle size (5-30 nm) with or without coating produced no activating effect on platelet aggregation caused by aggregation...

journal_title：Bulletin of experimental biology and medicine

authors： Aseychev AV,Azizova OA,Beckman EM,Dudnik LB,Sergienko VI

更新日期：2013-09-01 00:00:00

abstract：:Drug resistance and viability of Mycobacterium tuberculosis were studied in 637 patients with pulmonary tuberculosis, detected by screening fluorography (group 1) and in 909 patients in whom the specific process was detected when they applied for medical care (group 2). The mycobacteria in the two groups did not diffe...

journal_title：Bulletin of experimental biology and medicine

authors： Koretskaya NM,Narkevich AN

更新日期：2014-11-01 00:00:00

abstract：:Autooxidation of low-density lipoproteins during incubation at 37 degrees C was accompanied by accumulation of LPO products, decrease in UV autofluorescence (FUV), and increase in autofluorescence in the visible band (FVIS). The degree of low-density lipoprotein modification was estimated by calculating the FVIS/FUV r...

journal_title：Bulletin of experimental biology and medicine

authors： Aidyraliev RK,Azizova OA,Vakhrusheva TV,Lopukhin YM,Mirrakhimov MM

更新日期：2006-10-01 00:00:00

abstract：:Changes in the diurnal light cycle affect the morphofunctional state of the pineal gland. The volume of the nucleus, Golgi apparatus, and mitochondria in pinealocytes decreases after 45-day exposure to bright light. After 90 days, the degree of nuclear polymorphism increased, the specific volume of the Golgi apparatus...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimov AV,Logvinov SV,Kostyuchenko VP

更新日期：2010-12-01 00:00:00

abstract：:Formation of Ala-Glu-Asp-Gly peptide complex with duplex DNA [poly(dA-dT):poly(dA-dT)] at neutral pH and ambient temperature was studied experimentally. Peptide binding to duplex DNA was associated with hyperchromic effect indicating local separation of the double helix. Energies of paired interactions between amino a...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Solovyov AY,Shataeva LK

更新日期：2006-04-01 00:00:00

abstract：:Administration of granulocyte CSF preparation to patients with chronic heart failure produced a hemostimulating effect and increased the content of leukocytes and neutrophils in the peripheral blood. Granulocyte CSF induced mobilization of bone marrow progenitor cells into the peripheral blood. The content of hemopoie...

journal_title：Bulletin of experimental biology and medicine

authors： Konenkov VI,Pokushalov EA,Poveshchenko OV,Kim II,Romanov AB,Guleva NA,Bernvald VV,Soloviova AO,Yankayte EV,Poveshchenko AF,Karaskov AM

更新日期：2012-05-01 00:00:00

abstract：:We analyzed the dynamics of neuropathic pain development and changes in catalase and superoxide dismutase (SOD) activities in the brain, liver, and skeletal muscles of male Wistar rats with 1-month streptozotocin-induced diabetes mellitus. A decrease in mechanical nociceptive threshold was revealed that progressed dur...

journal_title：Bulletin of experimental biology and medicine

authors： Shipilov VN,Chistyakova OV,Trost AM

更新日期：2016-05-01 00:00:00

abstract：:We revealed a significant positive correlation between the concentrations of tissue VEGF and its receptor VEGFR2 in the primary tumor. The degree and direction of changes in the content of VEGF and VEGFR2 in cytosols of tumors from patients with locally spread breast cancer during the preoperation therapy depended on ...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EA,Gershtein ES,Vysotskaya IV,Kushlinskii NE

更新日期：2008-02-01 00:00:00