Abstract:
:Experiments on outbred albino rats showed that subacute poisoning with tetrachloromethane in a total dose of 1.0 LD50 appreciably decreased blood concentrations of cytokines (IFN-gamma, IL-2, IL-4, IL-6, IL-10), reduced the IFN-gamma/IL-4 ratio in comparison with the control, and suppressed the immune reactions, which attests to greater damage to Th1 compared to Th2 lymphocytes.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Zabrodskii PF,Kirichuk VF,Lim VG,Balashov SV,Svistunov AAdoi
10.1007/s10517-009-0449-7subject
Has Abstractpub_date
2009-01-01 00:00:00pages
52-4issue
1eissn
0007-4888issn
1573-8221journal_volume
147pub_type
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