In Vitro Effects of Lithium Carbonate on Cell Cycle, Apoptosis, and Autophagy in Hepatocellular Carcinoma-29 Cells.

abstract：:We studied the peculiarities of oxidative and substrate phosphorylation in isolated cardiomyocytes and myocardial mitochondria in 2- and 15-month-old rats. It was shown that age factor reduces the degree of oxidation and phosphorylation coupling both in cardiomyocytes and in mitochondria, which was associated with the...

journal_title：Bulletin of experimental biology and medicine

authors： Tsapko LP,Afanas'ev SA

更新日期：2019-08-01 00:00:00

abstract：:The effects of Biopin (ointment containing pine resin) used in the treatment of burns, wounds, and pyoinflammatory processes on cell composition of the wound surface (smears) and granulation tissue were studied on rats. In vitro antibacterial activity of the drug was also evaluated. At the early stage of inflammation ...

journal_title：Bulletin of experimental biology and medicine

authors： Simbirtsev AS,Konusova VG,Mchelidze GSh,Fidarov EZ,Paramonov BA,Chebotarev VY

更新日期：2002-05-01 00:00:00

abstract：:We studied the influence of pretreatment with chemical mildronate analogue sibusol on the course of experimental gastric ulcer in rats. Sibusol produced a protective effects on the stomach and duodenum. ...

journal_title：Bulletin of experimental biology and medicine

authors： Lychkova AE,Savchuk VI,Smirnov VM

更新日期：2004-01-01 00:00:00

abstract：:Arginine-vasopressin or arginine-vasotocin hormones introduced into the small intestine are absorbed and exert a hydrosmotic effect. The amount of absorbed antidiuretic hormone increased when it is introduced with intestinal peptidase inhibitor aprotinin. These data attest to the possibility of absorption of pituitary...

journal_title：Bulletin of experimental biology and medicine

authors： Natochin YV,Shakhmatova EI

更新日期：2004-01-01 00:00:00

abstract：:We studied in vitro cytostatic effect of doxorubicin on bone marrow cells preincubated with NAD and reduced glutathione. The presence of NAD and glutathione in the medium potentiated membrane toxicity of this antibiotic, but prevented its toxic effects on intracellular pool of pyridine nucleotides during oxidative str...

journal_title：Bulletin of experimental biology and medicine

authors： Egorova AB,Uspenskaya YA,Nefedov VP

更新日期：2001-07-01 00:00:00

abstract：:We revealed some relationships between the level of orientation and exploratory behavior, functional activity of the immune system, and structural and functional organization of the CNS in animals. Significant differences in brain morphology and expression of cytokine IL-1 beta, type I IL-1 receptor, and erythropoieti...

journal_title：Bulletin of experimental biology and medicine

authors： Markova EV,Chernova TG,Fillimonov PN,Korotkova NA,Abramov VV,Kozlov VA

更新日期：2004-10-01 00:00:00

abstract：:Number and size of aggregated lymphoid nodules in the small intestine of mice exposed to radiation using a γ-irradiation unit GOBO-60 with 137Cs source were measured using the methods of visual microscopy and morphometry. Morphological status of the nodules was estimated on days 4, 28, 60, and 90 after the exposure. S...

journal_title：Bulletin of experimental biology and medicine

authors： Klochkova SV,Kvaratskheliya AG,Alekseeva NT,Nikityuk DB

更新日期：2017-12-01 00:00:00

abstract：:We studied the interaction of neural stem cells and dental pulp-derived mesenchymal stem cells with lymphocytes from autologous and heterologous donors. Flow cytometry analysis with the use of CFSE-labeled lymphocytes demonstrated an increase in the content of proliferating CD8, CD16 and CD56 cells, but not CD4 cells ...

journal_title：Bulletin of experimental biology and medicine

authors： Svirshchevskaya EV,Poltavtseva RA,Beletskii IP,Selezneva II,Savilova AM,Sukhikh GT

更新日期：2016-08-01 00:00:00

abstract：:We studied the incidence of chromosome aberrations in bone marrow cells and primary spermatocytes in various mouse strains. Experiments were performed on SAMP mice (accelerated aging), control SAMR mice, and long-living CBA and SHR mice. Experiments revealed a positive correlation between the age and the incidence of ...

journal_title：Bulletin of experimental biology and medicine

authors： Rozenfel'd SV,Togo EF,Mikheev VS,Popovich IG,Zabezhinskii MA,Anisimov VN

更新日期：2001-05-01 00:00:00

abstract：:We studied the effects of selective delta-opiate receptor agonists and antagonists on the phosphoinositide pathway in lymphocytes from healthy donors and patients with diabetes mellitus. The test compounds probably play a role in changes in the sensitivity to pharmacological substances binding to delta-opiate receptor...

journal_title：Bulletin of experimental biology and medicine

authors： Agadjanov MI,Vartanian GS,Tadevosyan YV,Batikyan TB,Agadjanova EM

更新日期：2004-02-01 00:00:00

abstract：:We studied changes in cerebral and central hemodynamics during active orthostatic load in 26 healthy men aging 20-26 years. Two types of central hemodynamics were revealed: progressive increase in blood pressure throughout the test (type 1) or initial blood pressure increase followed by its decrease with maximum incre...

journal_title：Bulletin of experimental biology and medicine

authors： Zabolotskikh NV

更新日期：2008-05-01 00:00:00

abstract：:We studied biocompatibility and bioresorption of 3D-printed polylactide and polyglycolide tissue membranes. Ultrasound microscopy and histological examination showed that membranes fabricated of a copolymer of lactic and glycolic acids in a mass ratio of 1:9 are bioresorbed and have good biocompatibility with soft tis...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EV,Petronyuk YS,Guseynov NA,Tereshchuk SV,Popov AA,Volkov AV,Gorshenev VN,Olkhov AA,Levin VM,Dymnikov AB,Rodionov VE,Tumanyan GA,Ivashkevich SG,Bonartsev AP,Borozdkin LL

更新日期：2021-01-01 00:00:00

abstract：:We studied a biomaterial for a new domestic product, a biological envelope for implantation of cardiac electronic devices. The product is designed to prevent complications after pacemaker implantation and to facilitate the reimplantation procedure. By chemical and biological processing of raw materials (submucosa of p...

journal_title：Bulletin of experimental biology and medicine

authors： Shadrina DV,Venediktov AA,Evdokimov SV,Vaskovskii VA,Artyukhina EA,Revishvili AS,Durmanov SS,Bazylev VV

更新日期：2020-01-01 00:00:00

abstract：:Developed form of metabolic syndrome was revealed in 64.3% men with grade 1 obesity and in 81.8% men with grade 2-3 obesity (patients of the therapeutic clinic). The major components were dyslipidemia, fatty hepatosis, arterial hypertension, and hyperinsulinemia. In patients with excess body weight, changes in some bi...

journal_title：Bulletin of experimental biology and medicine

authors： Kogai MA,Lutov UV,Selyatitskaya VG

更新日期：2008-12-01 00:00:00

abstract：:Heart rate variability was examined in random-bred albino rats at rest. The rats were clusterized according to activity of autonomic contour of heart rate control. Combination of factor and cluster analyses enhanced informative value of spectrum parameters of the heart rate variability in nonlinear rats grouped by ini...

journal_title：Bulletin of experimental biology and medicine

authors： Kur'yanova EV,Teplyi DL,Savin VF

更新日期：2009-01-01 00:00:00

abstract：:The content of urokinase- and tissue-type plasminogen activators and plasminogen activator inhibitor PAI-1 in the cytosol of primary and metastatic melanomas and benign skin pigment neoplasms was estimated by enzyme immunoassay. It was shown that local growth and invasion of melanomas are related to suppressed express...

journal_title：Bulletin of experimental biology and medicine

authors： Gershtein ES,Medvedeva SV,Babkina IV,Kushlinskii NE,Trapeznikov NN

更新日期：2001-07-01 00:00:00

abstract：:We developed wound coating based on natural biopolymer chitosan with additional components (ceruloplasmin, L-asparaginic acid, and glycerol). Experiments on albino male rats demonstrated its regeneratory, antioxidant, and antibacterial effects on wounds involving all layers of the skin. Due to chemical composition and...

journal_title：Bulletin of experimental biology and medicine

authors： Gladkova EV,Babushkina IV,Norkin IA,Mamonova IA,Puchin'yan DM,Konyuchenko EA

更新日期：2016-03-01 00:00:00

abstract：:Analysis of planned endomyocardial biopsy specimens of heart allotransplants from 22 recipients revealed signs of humoral type rejection (slight, medium, and severe) presenting as fixation of IgG, IgM, and complement components (C3, C4d) in 61 of 63 sections. Permanent presence of rejection signs attests to rheumatoid...

journal_title：Bulletin of experimental biology and medicine

authors： Beletskaya LV,Kupriyanova AG,Kormer AY,Mironkov BL,Kazakov EN,Shumakov VI

更新日期：2006-09-01 00:00:00

abstract：:The level of antipaternal antileukocytic antibodies detected by flow cytometry is a parameter reflecting the efficiency of alloimmunization of women with reproductive disorders during preparation to pregnancy. The results of evaluation of antipaternal antileukocytic antibodies by two modifications of the method are pr...

journal_title：Bulletin of experimental biology and medicine

authors： Krechetova LV,Nikolaeva MA,Van'ko LV,Ziganshina MM,Golubeva EL,Stepanova EO,Sukhikh GT

更新日期：2012-09-01 00:00:00

abstract：:Analysis of placenta homogenate from pregnant women having an episode of herpes-virus infection during the third trimester revealed suppression of Bcl-2 protein activity and increase in caspase 3 concentration. Activity of Bcl-2 protein decreases with increasing the titer of antibodies to herpes virus. Increased caspa...

journal_title：Bulletin of experimental biology and medicine

authors： Lutsenko MT,Andrievskaya IA

更新日期：2010-10-01 00:00:00

abstract：:Neuroprotective effects of GABA(B) agonist baclofen and GABA(A) agonists THIP and muscimol are completely additive. GABAA and GABA(B) receptor antagonists block the neuroprotective effects of the corresponding agonists without cross-blocking. In fact, the blockade of combined effect of two agonists with selective GABA...

journal_title：Bulletin of experimental biology and medicine

authors： Kulinskii VI,Mikhel'son GV

更新日期：2000-08-01 00:00:00

abstract：:Oxidative modification of fibrinogen in acute myocardial infarction increased 1.3-fold compared to that in CHD and 1.5-fold surpassed that in the control without CHD. Elevated content of oxidized fibrinogen correlated with increased levels of LPO products, von Willebrand factor, and fibrin degradation products, with a...

journal_title：Bulletin of experimental biology and medicine

authors： Ragino YI,Baum VA,Polonskaya YV,Sadovski EV,Baum SR,Nikitin YP

更新日期：2008-04-01 00:00:00

abstract：:Antiaggregant activity of a new tricyclic benzimidazole derivative, RU-891 compound, was studied on the model of ADP-induced platelet aggregation in vitro and intravascular platelet aggregation in vivo. We evaluated the effect of this substance on blood coagulation potential. Antiaggregant agent acetylsalicylic acid w...

journal_title：Bulletin of experimental biology and medicine

authors： Kucheryavenko AF,Spasov AA,Petrov VI,Anisimova VA

更新日期：2014-04-01 00:00:00

abstract：:A new phenomenon (or paradox) consisting in higher statistical stability of samples, for example, tremorograms, in a group of different subjects than in the same subject in unchanged homeostasis. At the same time, it turns out that 15 different subjects are more similar (statistically) to each other than one person to...

journal_title：Bulletin of experimental biology and medicine

authors： Zilov VG,Khadartsev AA,Eskov VM,Ilyashenko LK

更新日期：2019-08-01 00:00:00

abstract：:Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level foll...

journal_title：Bulletin of experimental biology and medicine

authors： Kuznetsova NV,Palchikova NA,Selyatitskaya VG,Shkurupiy VA

更新日期：2010-11-01 00:00:00

abstract：:o-Aminoazotoluene in noncarcinogenic doses promoted the development of liver tumors in female ICR mice induced by administration of diethylnitrosamine during early ontogeny. Severe inflammatory infiltration and proliferation of oval cells were found in liver tissue of these animals. The concentration of free thyroxin ...

journal_title：Bulletin of experimental biology and medicine

authors： Baginskaya NV,Il'nitskaya SI,Nikitenko EV,Kaledin VI

更新日期：2007-12-01 00:00:00

abstract：:The mechanisms of extracardiac regulation of heart rate were studied in rats subjected to muscle training on a treadmill with different slope angle (0 degrees , 5.5 degrees up, and 5.5 degrees down). Muscle training on a treadmill sloping down was optimal for the development of training bradycardia in 70-day-old rats....

journal_title：Bulletin of experimental biology and medicine

authors： Abzalov RA,Ryabysheva SS

更新日期：2008-11-01 00:00:00

abstract：:Fifty-three transplantations of pituitary tissue (intact and minced with scissors) under the tunica albuginea testis were carried out. In both series pituitary cells retained viability for up to 6 months. Transplantation of cell suspension was not accompanied by the formation of necrotic zone in the transplant; the ad...

journal_title：Bulletin of experimental biology and medicine

authors： Dendeberov ES

更新日期：2001-02-01 00:00:00

abstract：:An open comparative clinical study evaluated the efficiency of Proproten-100 in reliving affective, somatovegetative, behavioral, and cognitive post-withdrawal disorders and manifestations of primary pathological alcohol addiction in patients with alcohol dependence in the stage of therapeutic remission. We compared t...

journal_title：Bulletin of experimental biology and medicine

authors： Bokhan NA,Abolonin AF,Krylov EN,Vetlugina TP,Ivanova SA,Epstein OI

更新日期：2003-01-01 00:00:00

abstract：:In patients with viral and bacterial infectious mononucleosis during the acute period of disease and clinical convalescence blood content of CD72(+)and CD16(+)lymphocytes increased compared to normal. The count of CD8(+)cells increased in viral mononucleosis during convalescence and these changes persist in delayed pe...

journal_title：Bulletin of experimental biology and medicine

authors： Novitskii VV,Urazova OI,Naslednikova IO,Pomogaeva AP,Syusina LV

更新日期：2002-07-01 00:00:00