Pine resin and Biopin ointment: effects on repair processes in tissues.

Abstract:

:The effects of Biopin (ointment containing pine resin) used in the treatment of burns, wounds, and pyoinflammatory processes on cell composition of the wound surface (smears) and granulation tissue were studied on rats. In vitro antibacterial activity of the drug was also evaluated. At the early stage of inflammation Biopin modulated the nonspecific and inhibited specific cell immune response, normalized hemodynamics in the inflammation focus, activated synthetic processes in the wound, and was effective towards anaerobes and bacilli.

journal_name

Bull Exp Biol Med

authors

Simbirtsev AS,Konusova VG,Mchelidze GSh,Fidarov EZ,Paramonov BA,Chebotarev VY

doi

10.1023/a:1019805603373

subject

Has Abstract

pub_date

2002-05-01 00:00:00

pages

457-60

issue

5

eissn

0007-4888

issn

1573-8221

journal_volume

133

pub_type

杂志文章
  • Using the matrix-assisted laser desorption ionization for the analysis of flavonoid glycosides in objects of plant origin.

    abstract::Data are presented on chemical study of flavonoid glycosides in some botanical subjects using matrix-assisted laser desorption ionization, compared to HPLC. The method of matrix-assisted laser desorption ionization (MALDI) allows characterizing the composition of anthocyanin and flavonoid mixture without preliminary s...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-013-1960-4

    authors: Novikov OO,Pisarev DI,Zhilyakova ET,Novikova MY,Pisareva NA,Voronkova OS,Bezmenova MD

    更新日期:2013-01-01 00:00:00

  • Possible neurophysiological markers of early neurodegenerative process: Parkinson's disease.

    abstract::We used tests for evaluation of latent period, duration, and accuracy of eyes, head, or hand movements and their coordinated movements. Comparative analysis of these parameters was performed in healthy subjects and in patients with early stages of Parkinson's disease. The pathology data significantly (p<0.05) differed...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-012-1907-1

    authors: Baziyan BKh

    更新日期:2012-12-01 00:00:00

  • Comparative Assessment of Leukocyte Infiltrate Composition in the Uterine and Vaginal Tissues in Rats with Experimental Endomyometritis Treated with Interferon-γ at Different Times of the Day.

    abstract::The cell composition of leukocyte infiltrates in the endometrium, myometrium, and vaginal walls was studied in Wistar rats with modeled chronic endomyometritis after administration of IFNγ (0.1 μg/100 g body weight) in different daily regimens (10.00 or 20.00). Morning injections of this cytokine ameliorated inflammat...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-020-04921-7

    authors: Dergacheva TI,Shurlygina AV,Abdalova AM,Klimontov VV,Trufakin VA,Letyagin AY

    更新日期:2020-08-01 00:00:00

  • Antiarrhythmic and arrhythmogenic effects of L-carnitine in ischemia and reperfusion.

    abstract::Isolated rat hearts were subjected to 30-min coronary artery occlusion followed by 120-min reperfusion. The hearts (n=8-12) were perfused with Krebs-Henseleit solution enriched with L-carnitine (0.5, 2.5 and 5 mM) for 10 min before and after ischemia or reperfusion and for the whole period of ischemia and reperfusion....

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-008-0249-5

    authors: Najafi M,Garjani A,Maleki N,Eteraf Oskouei T

    更新日期:2008-08-01 00:00:00

  • Lymphatic region of the uterus and adnexa during pregnancy after inflammation of internal genital organs.

    abstract::We studied the course and outcome of pregnancy in the model of inflammation of internal genital organs in female rats. It was shown that inflammation of internal genital organs impairing the state of the lymphatic region of the uterus and adnexa and relationship between the drainage and detoxification function therein...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-014-2672-0

    authors: Dergacheva TI,Borodin YI,Konenkov VI

    更新日期:2014-10-01 00:00:00

  • Blood lymphocyte proliferation reaction in autoimmune thyropathies.

    abstract::Spontaneous and stimulated reaction of lymphocyte proliferation and blood levels of CD25- and CD120-expressing lymphocytes were studied in patients with autoimmune thyroiditis and diffuse toxic goiter. Activation of CD25- and CD120-presenting function of blood lymphocytes was revealed. The findings indicate that the c...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-008-0278-0

    authors: Urazova OI,Kravets EB,Nedosekova YV,Rogaleva AV,Kuznecova VN,Rumpel OA

    更新日期:2008-09-01 00:00:00

  • Effects of a local focus of granulation tissue formed in the bone marrow cavity on reparative osteogenesis.

    abstract::The stimulatory effect of a local focus of granulation tissue, created in the bone marrow cavity, on reparative osteogenesis after tibial bone fracture was detected in experimental rats by microscopic examination of histological sections, scanning electron microscopy, and X-ray electron probe microanalysis. ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-014-2503-3

    authors: Ir'yanov YM,Dyuryagina OV

    更新日期:2014-05-01 00:00:00

  • Effects of Lys-Glu-Trp peptide on cell-cell interactions and vascular endothelium proliferation under normal conditions and during atherosclerosis.

    abstract::The molecular mechanism of atherosclerosis is based on decreased expression of signal molecules connexin (Cx37 and Cx40), vascular endothelial growth factor (VEGF), and proliferative protein Ki-67, which characterize the processes of cell-cell interactions and proliferation of vascular endotheliocytes. Lys-Glu-Trp pep...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-014-2556-3

    authors: Malinin VV,Durnova AO,Polyakova VO,Kvetnoi IM

    更新日期:2014-07-01 00:00:00

  • Contractile function of the heart and the state of some stages of lipid metabolism during acute diphtheritic intoxication.

    abstract::Acute diphtheritic intoxication was modeled in rabbits by intravenous administration of native diphtherin (0.3 minimal lethal dose per 1 kg body weight). The contractile function of the left and right ventricles (peak systolic pressure under conditions of basal hemodynamics and during 5-sec occlusion of the aorta and ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-010-0714-9

    authors: Blagonravov ML,Demurov EA,Frolov VA,Onufriev MV

    更新日期:2009-09-01 00:00:00

  • Reflection of induced and amplified food motivation in impulse activity of the masticatory muscles during electrostimulation of the "hunger center" in the lateral hypothalamus in rabbits.

    abstract::We studied reflection of artificially induced and amplified food motivation in impulse activity of the masticatory muscles during electrostimulation of "hunger center" of the lateral hypothalamus in the absence and presence of food. The threshold stimulation of the lateral hypothalamus in hungry and satiated animals i...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-012-1602-2

    authors: Ignatova JP,Kromin AA

    更新日期:2012-04-01 00:00:00

  • Deoxyribonuclease activity in biological fluids of healthy donors and cancer patients.

    abstract::Integral activity of neutral deoxyribonucleases in the plasma and urine or donors, patients with benign prostatic hyperplasia, and patients with stomach and prostatic cancer was studied by IFA based on hydrolysis of DNA fragment modified with haptene molecules. In donors plasma deoxyribonuclease activity was 0.16+/-0....

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-008-0213-4

    authors: Tamkovich SN,Cherepanova AV,Bryzgunova OE,Kolesnikova EV,Permyakova VI,Vlassov VV,Laktionov PP

    更新日期:2008-07-01 00:00:00

  • Experimental Study of Heart Functionality during Treatment of Chronic Heart Failure in Rats of Different Age Groups with Levosimendan (Experimental Study).

    abstract::Levosimendan is effective in the therapy of chronic heart failure in both mature and old rats, but the duration of its therapeutic effect differs in these age groups. In 15 days after treatment, the myocardium in old rats maintained augmented functionality, whereas in old animals, functional potencies returned to the ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-020-04815-8

    authors: Mamalyga ML,Mamalyga LM

    更新日期:2020-05-01 00:00:00

  • A Marker of Cerebral Ischemia in Solid State Structures of Blood Serum.

    abstract::Reversible cerebral ischemia of medium severity was reproduced in male Wistar rats by bilateral occlusion of the common carotid arteries. Solid-phase structures (anisomorphons) were obtained by marginal dehydration of the serum. Small focal isotropic defects in the serum anisomorphon texture were found in 100% cases d...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-018-3991-3

    authors: Shatokhina SN,Aleksandrin VV,Shatokhina IS,Kubatiev AA,Shabalin VN

    更新日期:2018-01-01 00:00:00

  • Antiviral activity of liposomal preparations of antibiotic geliomycin.

    abstract::A liposomal preparation with maximally possible content of incorporated geliomycin was obtained. Its cytotoxicity was studied in a culture of human embryonal diploid fibroblasts. Antiviral activity was studied on a model of cytomegaloviral infection in vitro by the capacity to plaque formation. Liposomal geliomycin wa...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-005-0291-5

    authors: Podol'skaya SV,Naryshkina NA,Sorokoumova GM,Kaplun AP,Fedorova NE,Medzhidova AA,Kuts AA,Shvets VI

    更新日期:2005-03-01 00:00:00

  • Prenatal Hyperhomocysteinemia Impairs Hypothalamic Regulation of Reproductive Cycles in Rat Progeny.

    abstract::Effects of prenatal hyperhomocysteinemia on hypothalamic regulation of estrous cycles were studied in female rats. In mature rats exposed to prenatal hyperhomocysteinemia, changes in the catecholamine content in hypothalamic areas responsible for the formation of the preovulatory surge of gonadotropin-releasing hormon...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-017-3701-6

    authors: Arutyunyan AV,Zaloznyaya IV,Kerkeshko GO,Milyutina YP,Korenevskii AV

    更新日期:2017-04-01 00:00:00

  • Effect of glyprolines on homeostasis of gastric mucosa in rats with stress ulcers.

    abstract::Pro-Gly-Pro and its metabolite Gly-Pro effectively prevented the development of erosive and ulcerative lesions of the gastric mucosa in rats under conditions of water-immersion restraint stress by restoring the oxidatant-antioxidant balance in the total fraction of gastric mucosa cells. Pro-Gly was least effective in ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-010-0866-7

    authors: Falalyeyeva TM,Samonina GE,Beregovaya TV,Andreeva LA,Dvorshchenko EV

    更新日期:2010-07-01 00:00:00

  • Content of HLA-G(+) T Cells in the Peripheral Blood from Healthy Women and Breast Cancer Patients.

    abstract::The number of CD3(+)CD56-HLA-G(+) cells in the peripheral blood of breast cancer patients was shown to increase by 2 times. Our results and published data suggest that the increase in the relative content of CD3(+)CD56-HLA-G(+) cells in the circulating blood in breast cancer contributes to tumor development due to sup...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-015-3038-y

    authors: Ostapchuk EO,Perfi L'eva YV,Talaeva ShZh,Omarbaeva NA,Belyaev NN

    更新日期:2015-09-01 00:00:00

  • Estimation of Expression of Oral Fluid Biomarkers in the Diagnosis of Pretumor Diseases of Oral Mucosa.

    abstract::Complex clinical, dental, and morphological investigation, and ELISA of levels of MMP-2, 8, 9, and TIMP-1 and 2 in the saliva was performed during primary examination of patients with premalignant lesions of maxillofacial area and practically healthy volunteers. Levels of all study MMP in the saliva significantly diff...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-017-3744-8

    authors: Kochurova EV,Nikolenko VN

    更新日期:2017-05-01 00:00:00

  • Seasonal effects of Selank on the behavior of hibernating animals.

    abstract::We studied the seasonal effects of peptide preparation Selank on orientation and exploratory activity in 36 arctic ground squirrels Citellus undulatus in the open-field and hole-board tests. Selank most significantly increased behavioral activity of hibernating animals in the spring and fall. The test peptide had no e...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-006-0060-0

    authors: Semenova TP,Kozlovskaya MM,Zuikov AV,Kozlovskii II,Andreeva LA

    更新日期:2005-12-01 00:00:00

  • Effect of Nanocrystalline Particles of Chitin on Blood Components in Humans and Experimental Animals.

    abstract::Nanocrystalline particles of chitin in the form of hydrosol in a concentration of 0.63 mg/ml have no effect on aggregation of human platelets and clotting time of platelet-poor plasma in coagulation tests. ADP-induced aggregation of human platelets was inhibited by these nanoparticles in concentrations of 0.63 and 1.0...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-018-4076-z

    authors: Drozd NN,Torlopov MA,Udoratina EV,Logvinova YS

    更新日期:2018-04-01 00:00:00

  • Circulating Proteasomes in the Pathogenesis of Head and Neck Squamous Cell Carcinoma.

    abstract::Increased proteasome activity was revealed in blood serum of patients with stage T1N0M0 head and neck squamous cell carcinoma in comparison with patients with chronic diseases of the larynx and laryngopharynx. This opens prospects of using chymotrypsin-like activity measurement for differential diagnosis of squamous c...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-017-3745-7

    authors: Kakurina GV,Cheremisina OV,Choinzonov EL,Kondakova IV

    更新日期:2017-05-01 00:00:00

  • Autoantibodies to neuron-specific proteins S100, GFAP, MBP and NGF in the serum of rats with streptozotocin-induced diabetes.

    abstract::The appearance of autoantibodies to neuronal proteins (S100, GFAP, MBP, and NGF) in rat serum was analyzed by ELISA on days 5, 10, 17, 25, and 32 after streptozotocin injection. Simultaneously, blood glucose and insulin autoantibodies were assayed. Serum glucose level increased on the next day after streptozotocin inj...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-013-2077-5

    authors: Lotosh NG,Savel'eva EK,Selishcheva AA,Savel'ev SV

    更新日期:2013-05-01 00:00:00

  • Fluorescent granular cells of the thymus can be identified as dendritic macrophages.

    abstract::Fluorescent granular cells of the thymus lobule containing neurotransmitter monoamines express Ia antigen and S-100 protein, which attests to their macrophage origin; positive staining with aldehyde fuchsin points to secretion of peptide hormones by these cells. These facts and the absence of phagocytic activity allow...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1023/a:1012552917439

    authors: Gordon DS,Sergeeva VE,Smorodchenko AT,Kirillov NA,Petrova TL,Olangin OI,Spirin IV

    更新日期:2001-07-01 00:00:00

  • Effect of epiphysectomy on the circadian dynamics of antiradical activity of chalone-antichalone system of albino rat liver.

    abstract::Antiradical activity of the chalone-antichalone system in the liver of albino rats is characterized by circadian rhythms. The production of tissue regulators of proliferation is synchronized with the 24-h light/darkness cycle. Active phase of the rhythm of antiradical activity falls on night hours. Epiphysectomy cause...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-008-0289-x

    authors: Slesarev SM,Arav VI,Antohin AI,Pashkov AN

    更新日期:2008-09-01 00:00:00

  • Effects of Thermoextracts of Brucella S and L Forms on Lipid Peroxidation and Antioxidant Defense in Organs of Laboratory Animals.

    abstract::The dynamics of LPO marker malondialdehyde formation and peroxidase-destroying activity was studied in homogenized organs of guinea pigs, immunized with thermoextracts from S and L forms Brucella abortus I-206. The L form brucella thermoextract exhibited a lower reactogenicity and adequately activated the antioxidant ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-018-4138-2

    authors: Dubrovina VI,Balakhonov SV,Yurieva OV,Starovoitova TP,Barannikova NL,Tokareva LE,Pyatidesyatnikova AB,Yastremskaya KY,Shkaruba TT

    更新日期:2018-06-01 00:00:00

  • Circadian rhythm of rectal reactivity in individuals with regular and irregular bowel evacuation function.

    abstract::Circadian dynamics of rectal reactivity was studied in humans with regular and irregular rhythms of bowel evacuation function by chronoenterography. In individuals with regular rhythm of this function (stool 7 days per week) the acrophase of circadian rhythm of rectal reactivity was observed in morning hours, while in...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1023/a:1022965212971

    authors: Shemerovskii KA

    更新日期:2002-12-01 00:00:00

  • Serum, liver, and lung levels of the major extracellular matrix components at the early stage of BCG-induced granulomatosis depending on the infection route.

    abstract::Experiments on the model of mouse BCG-induced granulomatous showed that the content of glycosaminoglycans and proteoglycans in the extracellular matrix of the liver and lungs are changed at the early stages of inflammation (days 3 and 30 postinfection) before cell destruction in the organs begins. This is related to d...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-015-2752-9

    authors: Kim LB,Shkurupy VA,Putyatina AN

    更新日期:2015-01-01 00:00:00

  • Interaction of Lymphocytes with Mesenchymal Stem Cells.

    abstract::We studied the interaction of neural stem cells and dental pulp-derived mesenchymal stem cells with lymphocytes from autologous and heterologous donors. Flow cytometry analysis with the use of CFSE-labeled lymphocytes demonstrated an increase in the content of proliferating CD8, CD16 and CD56 cells, but not CD4 cells ...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-016-3463-6

    authors: Svirshchevskaya EV,Poltavtseva RA,Beletskii IP,Selezneva II,Savilova AM,Sukhikh GT

    更新日期:2016-08-01 00:00:00

  • The Effect of Azithromycin on Biofilms Formation by Pathogens of Implant-Associated Infection in Large Joints.

    abstract::We studied the effect of subbacteriostatic azithromycin concentrations on the formation of microbial biofilms by Pseudomonas aeruginosa strains that caused implant-associated infection of large joints. Azithromycin in subinhibitory for planktonic cells concentrations 0.01-0.02 μg/ml stimulated biofilm formation by bot...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-020-04982-8

    authors: Babushkina IV,Ulyanov VY,Mamonova IA,Shpinyak SP

    更新日期:2020-10-01 00:00:00

  • Contribution of Hydrogen Sulfide to Dilation of Rat Cerebral Arteries after Ischemia/Reperfusion Injury.

    abstract::The study examined the effect of H2S on the tone of cerebral arteries in rats after global cerebral ischemia/reperfusion injury and cooperation between NO and H2S in the control over cerebral circulation during the postischemic period. In control sham-operated and in experimental rats with ischemia/reperfusion injury,...

    journal_title:Bulletin of experimental biology and medicine

    pub_type: 杂志文章

    doi:10.1007/s10517-020-04759-z

    authors: Lobov GI,Sokolova IB,Gorshkova OP,Shvetsova ME,Dvoretskii DP

    更新日期:2020-03-01 00:00:00