Interaction of Lymphocytes with Mesenchymal Stem Cells.

Abstract:

:We studied the interaction of neural stem cells and dental pulp-derived mesenchymal stem cells with lymphocytes from autologous and heterologous donors. Flow cytometry analysis with the use of CFSE-labeled lymphocytes demonstrated an increase in the content of proliferating CD8, CD16 and CD56 cells, but not CD4 cells in cultures of HLA-DR-negative mesenchymal stromal cells from the dental pulp co-cultured with lymphocytes. In neural cultures expressing HLA-DR, all subpopulations of T cells and NK cells were activated. No differences between the autologous and heterologous cultures were revealed.

journal_name

Bull Exp Biol Med

authors

Svirshchevskaya EV,Poltavtseva RA,Beletskii IP,Selezneva II,Savilova AM,Sukhikh GT

doi

10.1007/s10517-016-3463-6

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

571-9

issue

4

eissn

0007-4888

issn

1573-8221

pii

10.1007/s10517-016-3463-6

journal_volume

161

pub_type

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