Abstract:
:T cells were most sensitive to cyclophosphamide in DBA/2 mice, while in C57Bl/6 mice both T and B cells were sensitive. The formation of antibody-producing cells and the production of specific antibodies were delayed in DBA/2 mice immunized after pretreatment with antitumor drug. Accumulation of antibody-producing cells in the spleen was more active in immunized C57Bl/6 mice treated with cyclophosphamide compared to animals not treated with cyclophosphamide.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Masnaya NV,Churin AA,Borsuk OS,Sherstoboev EYdoi
10.1023/a:1024664815450subject
Has Abstractpub_date
2003-04-01 00:00:00pages
365-9issue
4eissn
0007-4888issn
1573-8221journal_volume
135pub_type
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