Anticonvulsant Effects of Combined Treatment with Citicoline and Valproate on the Model of Acute Generalized Convulsions Induced by Pentylenetetrazole in Wistar Rats.

abstract：:In August rats more resistant to acute stress-induced gastric damage than Wistar rats, preadaptation to nondamaging stress exposure did not prevent damage and even potentiated these damages. By contrast, in Wistar rats such adaptation decreased gastric damage caused by acute stress. Higher initial resistance of August...

journal_title：Bulletin of experimental biology and medicine

authors： Pshennikova MG,Popkova EV,Shimkovich MV

更新日期：2002-10-01 00:00:00

abstract：:Intraperitoneal injection of Semax (synthetic analogue of ACTH4-7, MEHFPGP) in a dose of 50 mg/kg produced a protective effect on rats with experimental indomethacin-induced ulcers. Experiments on narcotized rats showed that Semax in the studied dose had no effect on basal blood flow in the stomach, but prevented redu...

journal_title：Bulletin of experimental biology and medicine

authors： Zhuikova SE,Sergeev VI,Samonina GE,Myasoedov NF

更新日期：2002-06-01 00:00:00

abstract：:The appearance of autoantibodies to neuronal proteins (S100, GFAP, MBP, and NGF) in rat serum was analyzed by ELISA on days 5, 10, 17, 25, and 32 after streptozotocin injection. Simultaneously, blood glucose and insulin autoantibodies were assayed. Serum glucose level increased on the next day after streptozotocin inj...

journal_title：Bulletin of experimental biology and medicine

authors： Lotosh NG,Savel'eva EK,Selishcheva AA,Savel'ev SV

更新日期：2013-05-01 00:00:00

abstract：:A new phenomenon (or paradox) consisting in higher statistical stability of samples, for example, tremorograms, in a group of different subjects than in the same subject in unchanged homeostasis. At the same time, it turns out that 15 different subjects are more similar (statistically) to each other than one person to...

journal_title：Bulletin of experimental biology and medicine

authors： Zilov VG,Khadartsev AA,Eskov VM,Ilyashenko LK

更新日期：2019-08-01 00:00:00

abstract：:We studied a combined effect of subcomponents of vitamin B complex on the growth, development, and death of human embryonic brain-derived cells (E90) cultured using a modified method of Matson. Cell death was detected by trypan blue staining. According to our results, vitamin B-complex in low-doses promote the develop...

journal_title：Bulletin of experimental biology and medicine

authors： Danielyan KE,Abramyan RA,Galoyan AA,Kevorkian GA

更新日期：2011-09-01 00:00:00

abstract：:The concentration of tissue inhibitor of type 1 metalloproteinases in blood serum from intact CBA mice measured by enzyme immunoassay is similar to that in healthy humans. The concentration of tissue inhibitor of type 1 metalloproteinases in mouse bile was higher than in blood serum, while its concentration in liver h...

journal_title：Bulletin of experimental biology and medicine

authors： Korolenko TA,Filatova TG,Savchenko NG,Yuz'ko YV,Goncharova IA,Alexeenko TV

更新日期：2007-03-01 00:00:00

abstract：:Experiments on male and female CC57BR/Mv mice differing by the sensitivity to carcinogenic effect of urethane on the lungs showed that castration 1 week before carcinogen challenge reduced the number of lung adenomas caused by it in males and somewhat increased the number of tumors in females. Exogenous testosterone a...

journal_title：Bulletin of experimental biology and medicine

authors： Morozkova TS,Kaledin VI

更新日期：2015-10-01 00:00:00

abstract：:Study of the arteriovenous difference in hormone levels and hemostasis parameters in rats with experimental gestosis induced by hyper-sodium diet showed decreased production of progesterone, increased level of hydrocortisone (resultant from its increased production and additional release of the hormone by the lungs), ...

journal_title：Bulletin of experimental biology and medicine

authors： Myasnikova VV,Lysenkov SP,Galenko-Yaroshevskii PA,Barbakidze TR,Sukoyan GV

更新日期：2005-07-01 00:00:00

abstract：:At the early stages of development (3 months), transplants from bone marrow donors subjected to single in vivo stimulation (curettage, administration of BMP-2 or antigenic complex of S. typhimurium) 1 day before transplantation were characterized by significantly elevated content of nucleated cells (by 1.4, 1.9 and 2....

journal_title：Bulletin of experimental biology and medicine

authors： Gorskaya YF,Nesterenko VG

更新日期：2017-05-01 00:00:00

abstract：:We developed an optimal protocol for preparing and culturing of olfactory ensheathing cells from human olfactory mucosa. Using this protocol, we obtained a culture enriched with human olfactory ensheathing cells. Immunofluorescence analysis by simultaneous expression of GFAP and p75NTR markers showed that the content ...

journal_title：Bulletin of experimental biology and medicine

authors： Voronova АD,Stepanova OV,Valikhov MP,Chadin AV,Dvornikov АS,Reshetov IV,Chekhonin VP

更新日期：2018-03-01 00:00:00

abstract：:Immunohistochemistry with semi-quantitative analysis of computer images showed that prolactin receptor and cystic fi brosis transmembrane regulator (CFTR) in cholangiocytes of female rats elevated in cholestasis quickly respond to its relief. The effect of hyperprolactinemia on the extent of return of these proteins t...

journal_title：Bulletin of experimental biology and medicine

authors： Aleksandrova MI,Sirotina NS,Smirnova OV

更新日期：2015-07-01 00:00:00

abstract：:Immunocytochemical study has shown that Ki-67 antigen is detected in adenomyosis in both endometrial and myometrial cell populations (in the eutopic and ectopic endometrial glandular epithelium, stromal cells, smooth muscle cells, and vascular endotheliocytes of the endometrium and myometrium), the label index differi...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh LM,Lushnikova EL,Molodykh OP,Pichigina AK

更新日期：2013-08-01 00:00:00

abstract：:We studied the interaction of neural stem cells and dental pulp-derived mesenchymal stem cells with lymphocytes from autologous and heterologous donors. Flow cytometry analysis with the use of CFSE-labeled lymphocytes demonstrated an increase in the content of proliferating CD8, CD16 and CD56 cells, but not CD4 cells ...

journal_title：Bulletin of experimental biology and medicine

authors： Svirshchevskaya EV,Poltavtseva RA,Beletskii IP,Selezneva II,Savilova AM,Sukhikh GT

更新日期：2016-08-01 00:00:00

abstract：:The content of MMP-8 and MMP-9 in oral fluid of 145 patients (95 women and 50 men, 18-52 years) was measured by enzyme immunoassay. We examined 63 subjects with the intact periodontium and 82 patients with chronic generalized periodontitis (25 patients with mild disease, 45 patients with moderate disease, and 12 patie...

journal_title：Bulletin of experimental biology and medicine

authors： Kushlinskii NE,Solovykh EA,Karaoglanova TB,Bayar U,Gershtein ES,Troshin AA,Kostyleva OI,Grinin VM,Maksimovskaya LN,Yanushevitch OO

更新日期：2011-12-01 00:00:00

abstract：:Experiments on rats showed that activation of the peripheral ion channel TRPM8 with menthol and rapid cooling (decrease in core temperature by 3°C) led to 1.5-fold activation of the expression of TRPV3 ion channel gene in the posterior hypothalamus, but had no effect on the expression of this gene in the anterior hypo...

journal_title：Bulletin of experimental biology and medicine

authors： Kozyreva TV,Evtushenko AA,Voronova IP,Khramova GM,Kozaruk VP

更新日期：2018-12-01 00:00:00

abstract：:The kinetics of thrombin inhibition by irons ions was studied in the thrombin time test with normal plasma. The kinetic and concentration characteristics for recovery of thrombin activity by desferal were evaluated at various periods of thrombin incubation with iron ions. The thrombin time test showed that incubation ...

journal_title：Bulletin of experimental biology and medicine

authors： Azizova OA,Shvachko AG,Aseichev AV

更新日期：2009-11-01 00:00:00

abstract：:Cell cultures isolated from human endometrium by enzyme digestion consisted of highly viable fibroblast-like mesenchymal cells expressing CD90, CD73, and CD105. During passage 1, the cultures contained a small fraction of cytokeratin-7(+) epithelial cells that disappeared by passage 2. The cultures from the endometriu...

journal_title：Bulletin of experimental biology and medicine

authors： Savilova AM,Yushina MN,Rudimova YV,Khil'kevich EG,Chuprynin VD

更新日期：2016-02-01 00:00:00

abstract：:We studied the involvement of protein kinase Mζ (PKMζ) in the mechanisms of amnesia development within 10 days after disruption of conditioned food aversion memory with ZIP (a PKMζ inhibitor). Repeated training performed in 3 days after amnesia induction with ZIP, led to the formation of conditioned food aversion memo...

journal_title：Bulletin of experimental biology and medicine

authors： Nikitin VP,Solntseva SV,Kozyrev SA

更新日期：2019-10-01 00:00:00

abstract：:Ready dosage form (eye drops) prepared on the basis of recombinant alpha2-IFN exhibits high activity towards herpes simplex type 1 virus in vitro. Systematic study of the antiherpesvirus effect of this drug in combination with modified nucleosides showed an inhibitory effect of the synergic type. Combination of IFN pr...

journal_title：Bulletin of experimental biology and medicine

authors： Vyzhlova EN,Andronova VL,Galegov GA,Malinovskaya VV

更新日期：2006-06-01 00:00:00

abstract：:Experiments on cultured peritoneal macrophage from mice with HA-1 ascitic hepatoma showed that plasma lipoproteins present in the incubation medium decreased intracellular concentration of interleukin-1beta. These changes were most pronounced for high-density lipoproteins (alone or in combination with cortisol). Bacte...

journal_title：Bulletin of experimental biology and medicine

authors： Polyakov LM,Sumenkova DV,Panin LE

更新日期：2009-04-01 00:00:00

abstract：:Morphological changes in the mesenteric lymph nodes of male C57Bl/6 mice and subpopulation composition of lymphocytes in these nodes were studied in experimental acute and chronic ulcerative colitis induced by sodium dextran sulfate. Acute and chronic ulcerative colitis was associated with the development of reactive ...

journal_title：Bulletin of experimental biology and medicine

authors： Postovalova EA,Khochansky DN,Zolotova NA,Gao Y,Makarova OV,Dobrynina MT

更新日期：2016-04-01 00:00:00

abstract：:The involvement of the studied signal cascades in the regulation of erythropoietin production by bone marrow nuclears under conditions of immobilization stress depends on the type of the hemopoiesis-inducing microenvironment cells and the period of blood system reaction to stress exposure. Secretory activity of monocy...

journal_title：Bulletin of experimental biology and medicine

authors： Miroshnichenko LA,Zhdanov VV,Udut EV,Polyakova TY,Zyuz'kov GN,Simanina EV,Sherstoboev EY,Stavrova LA,Agafonov VI,Minakova MY,Chaikovskii AV,Dygai AM

更新日期：2017-07-01 00:00:00

abstract：:Blood levels of stem cell marker proteins CD34 and osteonectin were studied in male patients with coronary atherosclerosis by direct biomagnetic separation of proteins with magnetic microspheres using the PureProteome Protein A and Protein G Magnetic Beads proteomic technology. High concentration of osteonectin in the...

journal_title：Bulletin of experimental biology and medicine

authors： Ragino YI,Kashtanova EV,Chernjavski AM,Volkov AM,Polonskaya YV,Tsimbal SY,Eremenko NV,Ivanova MV

更新日期：2011-07-01 00:00:00

abstract：:Total antioxidant activity of the serum in patients with liver pathology was assessed by two chemiluminescent methods based on different models of free radical oxidation: Hb-H2O2-luminol and ABAP-luminol. Comparative analysis showed a significant, but not high correlation of the results (r=0.798), which can be explain...

journal_title：Bulletin of experimental biology and medicine

authors： Titov VN,Sazhina NN

更新日期：2014-12-01 00:00:00

abstract：:Data are presented on chemical study of flavonoid glycosides in some botanical subjects using matrix-assisted laser desorption ionization, compared to HPLC. The method of matrix-assisted laser desorption ionization (MALDI) allows characterizing the composition of anthocyanin and flavonoid mixture without preliminary s...

journal_title：Bulletin of experimental biology and medicine

authors： Novikov OO,Pisarev DI,Zhilyakova ET,Novikova MY,Pisareva NA,Voronkova OS,Bezmenova MD

更新日期：2013-01-01 00:00:00

abstract：:Morphofunctional evaluation of the effect of biological dressing with collagen-1 on healing of 3A degree burn wound in outbred and mutant Hr(hr)/Hr(hr)(hairless) mice was carried out by the histological method and optic radioautography. A pronounced stimulatory effect of the dressing on skin regeneration in mice was d...

journal_title：Bulletin of experimental biology and medicine

authors： Kolokolchikova EG,Zhirkova EA,Golovatenko-Abramov PK,Platonov ES,Botcharova VS,Khvatov VB

更新日期：2010-07-01 00:00:00

abstract：:Experiments on stationary culture of posterior eye and roll-bottle culture of the whole eye from adult water lizards Pleurodeles waltl showed that sclera bioregulator produces a stabilizing effects on adhesion interactions between the sclera, choroid, and pigment epithelium and on the maintenance of viability of scler...

journal_title：Bulletin of experimental biology and medicine

authors： Yamskova VP,Krasnov MS,Skripnikova VS,Yamskov IA

更新日期：2010-10-01 00:00:00

abstract：:Enlargement of the brain weight was attained in rats by reducing the number of neonates in the litter. The brain of 14- and 30-day-old animals was examined (controls: intact animals from litters of average numbers). Difference between the brain weight at 14 and 30 days was about 200 mg. The parameter in the experiment...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva EM

更新日期：2012-11-01 00:00:00

abstract：:We studied the role of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) in functional differentiation of HC11 mouse mammary gland cells. It was found that both IGF-1 and IGF-2 activate the expression of milk protein β-casein in the presence of prolactin and hydrocortisone. It was found that β-casein expression is...

journal_title：Bulletin of experimental biology and medicine

authors： Shushanov SS

更新日期：2011-12-01 00:00:00

abstract：:Antiradical activity of the chalone-antichalone system in the liver of albino rats is characterized by circadian rhythms. The production of tissue regulators of proliferation is synchronized with the 24-h light/darkness cycle. Active phase of the rhythm of antiradical activity falls on night hours. Epiphysectomy cause...

journal_title：Bulletin of experimental biology and medicine

authors： Slesarev SM,Arav VI,Antohin AI,Pashkov AN

更新日期：2008-09-01 00:00:00