Abstract:
:The involvement of the studied signal cascades in the regulation of erythropoietin production by bone marrow nuclears under conditions of immobilization stress depends on the type of the hemopoiesis-inducing microenvironment cells and the period of blood system reaction to stress exposure. Secretory activity of monocytes is regulated mainly by PI3K improving cell resistance to disturbances. The functional role of signal cascades involved in the production of erythropoietin by T cells is determined by the stage of the common adaptation syndrome.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Miroshnichenko LA,Zhdanov VV,Udut EV,Polyakova TY,Zyuz'kov GN,Simanina EV,Sherstoboev EY,Stavrova LA,Agafonov VI,Minakova MY,Chaikovskii AV,Dygai AMdoi
10.1007/s10517-017-3802-2subject
Has Abstractpub_date
2017-07-01 00:00:00pages
352-355issue
3eissn
0007-4888issn
1573-8221pii
10.1007/s10517-017-3802-2journal_volume
163pub_type
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