Abstract：
:Morphofunctional evaluation of the effect of biological dressing with collagen-1 on healing of 3A degree burn wound in outbred and mutant Hr(hr)/Hr(hr)(hairless) mice was carried out by the histological method and optic radioautography. A pronounced stimulatory effect of the dressing on skin regeneration in mice was demonstrated. According to radioautography data, early dressing of the burn wounds in Hr(hr)/Hr(hr)mice led to active proliferation of epithelial cells in dermal cyst and vascular endotheliocytes. The possible mechanisms of the stimulatory effect of collagen-based dressing on wound healing are discussed.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Kolokolchikova EG,Zhirkova EA,Golovatenko-Abramov PK,Platonov ES,Botcharova VS,Khvatov VBdoi
10.1007/s10517-010-0896-1subject
Has Abstractpub_date
2010-07-01 00:00:00pages
154-60issue
1eissn
0007-4888issn
1573-8221journal_volume
149pub_type
杂志文章abstract：:An important role in the development of the immune response is played by macrophages that acquire either anti-inflammatory M1 or anti-inflammatory M2 phenotype depending on their microenvironment. The possibility of targeted reprogramming of the initial M2 macrophage phenotype towards M1 phenotype and vice versa using...
journal_title：Bulletin of experimental biology and medicine
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doi：10.1007/s10517-012-1572-4
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abstract：:We studied anticonvulsant effects of combined treatment with citicoline, a nootropic substance with neuroregenerative and neuroprotective activities, and valproate, an antiepileptic agent widely used in the treatment of epilepsy, on the model of pentylenetetrazole-induced (75 mg/kg, intraperitoneally) acute generalize...
journal_title：Bulletin of experimental biology and medicine
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doi：10.1007/s10517-016-3188-6
更新日期：2016-02-01 00:00:00
abstract：:A test system developed by the authors was used to measure serum concentrations of soluble Fas in patients with malignant and benign tumors of different location and morphology. Relationships between soluble Fas levels and the main clinical and morphological characteristics of cancer were evaluated. It is proven that ...
journal_title：Bulletin of experimental biology and medicine
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doi：10.1007/s10517-010-0784-8
更新日期：2009-10-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1021563703378
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abstract：:We studied the phospholipid composition of high-density lipoproteins in patients with hypercholesterolemia before and after treatment with simvastatin. Individual phospholipids were separated by thin-layer chromatography on glass plates coated with silica gel. It was found that apart from hypolipidemic effect, simvast...
journal_title：Bulletin of experimental biology and medicine
pub_type： 临床试验,杂志文章
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更新日期：2001-08-01 00:00:00
abstract：:Fibroblasts isolated from skin biopsy specimens from patients with genetic forms of Parkinson's disease, carriers of mutations in LRRK2 and PARK2 genes, and from a healthy volunteer were reprogrammed using lentiviral vectors into induced pluripotent stem cells (iPSC). iPSC were differentiated into neuron-like cells us...
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journal_title：Bulletin of experimental biology and medicine
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更新日期：2014-08-01 00:00:00
abstract：:We compared the level of transforming growth factor-β1 (TGF-β1) in the tear fluid of 20 patients with high myopia who underwent transepithelial photorefractive keratectomy (T-PRK) in one eye and laser subepithelial keratomileusis (LASEK) in the contralateral eye. Tear fluid samples were collected with scaled microcapi...
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更新日期：2006-12-01 00:00:00
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更新日期：2011-08-01 00:00:00
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更新日期：2003-02-01 00:00:00
abstract：:Metabolic processes in the brain cortex of albino rats with prenatal and postnatal alcohol intoxication were studied by the method of electron paramagnetic resonance. Accumulation of superoxide radical-generating agents, inactivation of superoxide dismutase, and increase in nitric oxide concentration were detected. Ac...
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journal_title：Bulletin of experimental biology and medicine
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更新日期：2008-03-01 00:00:00
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更新日期：2008-05-01 00:00:00
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更新日期：2016-04-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
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journal_title：Bulletin of experimental biology and medicine
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1019805603373
更新日期：2002-05-01 00:00:00
abstract：:The study examined the effect of endogenous lipid-soluble antioxidant coenzyme Q10 on the expression of UbiA gene of prenyltransferase domain-containing protein 1 (UbiAd1) involved in synthesis of vitamin K2 (and probably of coenzyme Q10) on a rat model of ischemic stroke provoked by ligation of the middle cerebral ar...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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更新日期：2018-05-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-010-0845-z
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