Transplantation of bone marrow mononuclear cells does not affect postinfarction electrical remodeling of the heart.

Abstract:

:We studied the effect of allotransplantation of bone marrow mononuclear cells on postinfarction remodeling of the heart in rats. The cells were transplanted into the periinfarction zone of the heart. The transplantation was performed on day 9 after coronary occlusion. It was found that on day 45 after coronary occlusion myocardial hypertrophy developed, ventricular fibrillation threshold decreased, but myocardial contractility remained within the normal. Allotransplantation of bone marrow mononuclear cells had no effect on myocardial hypertrophy and did not prevent the development of electrical instability of the heart.

journal_name

Bull Exp Biol Med

authors

Maslov LN,Shakhov VP,Krylatov AV,Platonov AA

doi

10.1007/s10517-008-0029-2

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

129-32

issue

1

eissn

0007-4888

issn

1573-8221

journal_volume

145

pub_type

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