A new method for express analysis of flavonoid fraction in nephrophite plant extract and prediction of its antioxidant effects.

abstract：:We studied changes in cell cycle and apoptosis in normal keratinocytes and melanocytes after exposure to UV-B radiation. UV-B radiation modulated proliferation rate in the studied cell and produced an apoptosis-modulating effect in epidermal melanocytes. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ruksha TG

更新日期：2009-05-01 00:00:00

abstract：:Peroral administration of alpha-tocopherol in a daily dose of 150 mg/kg for 1, 4, 8, and 12 days leads to induction of cytochromes P450 1A in male rats. Activity of CYP1A1 and CYP1A2 increased most significantly one day after alpha-tocopherol administration (by 2.6 and 2.7 times, respectively). CYP1A1 was immunohistoc...

journal_title：Bulletin of experimental biology and medicine

authors： Sidorova YA,Grishanova AY,Lyakhovich VV

更新日期：2004-09-01 00:00:00

abstract：:A series of short neurotoxins (molecular weight 3500-5000 D) was isolated from Vietnamese scorpion B. occitanus sp. All these toxins blocked generation of action potentials (this effect depended on their molecular weight), but did not change conduction velocity and excitation threshold of the nerve. ...

journal_title：Bulletin of experimental biology and medicine

authors： Hoang NA,Maksimov GV,Berezin BB,Piskarev VE,Yamskov IA

更新日期：2001-10-01 00:00:00

abstract：:We used tests for evaluation of latent period, duration, and accuracy of eyes, head, or hand movements and their coordinated movements. Comparative analysis of these parameters was performed in healthy subjects and in patients with early stages of Parkinson's disease. The pathology data significantly (p<0.05) differed...

journal_title：Bulletin of experimental biology and medicine

authors： Baziyan BKh

更新日期：2012-12-01 00:00:00

abstract：:The efficiency of drug therapy should be evaluated by not only its directed action on specific organ or target parameter, but also its effects on general regulatory and adaptive status. ...

journal_title：Bulletin of experimental biology and medicine

authors： Pokrovskii VM,Kompaniets OG

更新日期：2008-06-01 00:00:00

abstract：:Fucoidans isolated from Fucus evanescens and Laminaria cichorioides kelp can inhibit thrombin and factor Xa of the blood coagulation system. In rats, intravenous injection of fucoidans dose-dependently increased anticoagulant activity of the plasma. Fucoidans can form complexes with protamine sulfate. The observed qua...

journal_title：Bulletin of experimental biology and medicine

authors： Drozd NN,Tolstenkov AS,Makarov VA,Kuznetsova TA,Besednova NN,Shevchenko NM,Zvyagintseva TN

更新日期：2006-11-01 00:00:00

abstract：:The effects of norepinephrine on the heart rate were studied in 1-, 3-, 6-, and 20-week-old rats before and after blockade of hyperpolarization-activated currents (I f , I h ). In animals with mature sympathetic regulation of cardiac activity (6- and 20-week-old animals), I f blockage decreased the severity of norepin...

journal_title：Bulletin of experimental biology and medicine

authors： Ziyatdinova NI,Dement'eva RE,Khisamieva LI,Zefirov TL

更新日期：2013-11-01 00:00:00

abstract：:The rate and strength of heart contractions decreased after 10-min perfusion of rat myocardium with Krebs-Henseleit solution containing a selective cannabinoid receptor agonist HU-210 in a final concentration of 10 nM. HU-210 completely blocked the positive inotropic and chronotropic effect of beta-adrenoceptor agonis...

journal_title：Bulletin of experimental biology and medicine

authors： Maslov LN,Lasukova OV,Krylatov AV,Uzhachenko RV,Pertwee R

更新日期：2004-12-01 00:00:00

abstract：:Significant associations between clinical history factors, lipid metabolism parameters, and type of atherosclerotic process (area of vascular lesions and severity of clinical manifestations) were detected. The predominance of generalized atherosclerosis in chronic coronary heart disease group was associated with patie...

journal_title：Bulletin of experimental biology and medicine

authors： Bakarev MA,Karpova AA,Pichigin VI,Nikityuk DB,Lushnikova EL

更新日期：2016-12-01 00:00:00

abstract：:The levels of natural antibodies to β-endorphin, bradykinin, histamine, dopamine, and serotonin were measured in 271 cardiological patients in order to evaluate the severity of their clinical status. The patients were distributed into groups differing by the course of the pathological process. The levels of natural an...

journal_title：Bulletin of experimental biology and medicine

authors： Morozova VS,Petrochenko SN,Myagkova MA,Bachurin SO

更新日期：2017-05-01 00:00:00

abstract：:We studied anticonvulsant effects of combined treatment with citicoline, a nootropic substance with neuroregenerative and neuroprotective activities, and valproate, an antiepileptic agent widely used in the treatment of epilepsy, on the model of pentylenetetrazole-induced (75 mg/kg, intraperitoneally) acute generalize...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova MN,Kuznetsova LV,Zin'kovskii KA,Klishina NV

更新日期：2016-02-01 00:00:00

abstract：:Changes in blood pressure and sympathetic nerve activity induced by local injection of endothelin-1 into the rostroventrolateral medulla were studied in narcotized stroke-prone spontaneously hypertensive rats (SHRSP) and normotensive WKY rats. Endothelin-1 produced similar biphasic response in both rat strains: a tran...

journal_title：Bulletin of experimental biology and medicine

authors： Ponomareva TI,Khokhlova ON,Tukhovskaya EA,Murashov AM

更新日期：2003-03-01 00:00:00

abstract：:We studied the correlation between the rank and age of baboons (n=12) with their cognitive abilities. A positive correlation was found between performances of different tests by male. The ability to solve the tests related to bait placement depended on the age of the males and age-related hierarchical status. Four-yea...

journal_title：Bulletin of experimental biology and medicine

authors： Anikaev AE,Chalyan VG,Meishvili NV

更新日期：2018-08-01 00:00:00

abstract：:Comparative analysis of proteoglycans in the control and tumor tissue of human mammary gland revealed disorders in the biosynthesis of dermatan sulfate proteoglycans in tumor cells. Using the methods of reverse transcription-PCR and Western blotting for the analysis of decorin expression we showed that these disorders...

journal_title：Bulletin of experimental biology and medicine

authors： Rykova VI,Grigorieva EV,Chernenko AV,Eshenko TY,Dymshits GM

更新日期：2007-09-01 00:00:00

abstract：:Precise location of IL-18 in cell and tissue elements of the atherosclerotic lesions in humans and its role in destabilization of the atherosclerotic plaque were detected. The data suggested a hypothesis on indirect involvement of IL-18 in destruction of the elastic and collagen fibers in an unstable plaque due to thi...

journal_title：Bulletin of experimental biology and medicine

authors： Pigarevskii PV,Maltseva SV,Snegova VA,Davydova NG

更新日期：2014-10-01 00:00:00

abstract：:We studied the role of cAMP- and IKK-2-dependent pathways under conditions of functional stimulation of mesenchymal progenitor cells by basic fibroblast growth factor. An adenylate cyclase inhibitor 2',5'-dideoxyadenosine had no effect on functional activity of early (primitive) mesenchymal precursors. This agent prod...

journal_title：Bulletin of experimental biology and medicine

authors： Zyuz'kov GN,Zhdanov VV,Danilets MG,Udut EV,Miroshnichenko LA,Ligacheva AA,Simanina EV,Chaikovskii AV,Trofimova ES,Minakova MY,Udut VV,Dygai AM

更新日期：2014-06-01 00:00:00

abstract：:The dynamics of coenzyme Q10 concentration in the blood plasma, liver, and brain of passive and active rats was studied on the model of metabolic stress. This parameter was shown to differ in rats with various patterns of behavior. Dietary consumption of coenzyme Q10 in doses of 10 and 100 mg/kg body weight was follow...

journal_title：Bulletin of experimental biology and medicine

authors： Kirbaeva NV,Sharanova NE,Baturina VA,Zhminchenko VM,Pertsov SS,Vasil'ev AV

更新日期：2016-09-01 00:00:00

abstract：:Testosterone and its high-molecular-weight form (testosterone covalently immobilized on bovine serum albumin) induced a rise of intracellular calcium concentration. The effectiveness of dihydrotestosterone was much lower compared to that of testosterone. Gestagens drospirenone and, to a lesser extent, 17alpha-acetoxy-...

journal_title：Bulletin of experimental biology and medicine

authors： Popova NY,Dukhanin AS,Shimanovskii NL

更新日期：2007-05-01 00:00:00

abstract：:The cell composition of leukocyte infiltrates in the endometrium, myometrium, and vaginal walls was studied in Wistar rats with modeled chronic endomyometritis after administration of IFNγ (0.1 μg/100 g body weight) in different daily regimens (10.00 or 20.00). Morning injections of this cytokine ameliorated inflammat...

journal_title：Bulletin of experimental biology and medicine

authors： Dergacheva TI,Shurlygina AV,Abdalova AM,Klimontov VV,Trufakin VA,Letyagin AY

更新日期：2020-08-01 00:00:00

abstract：:We studied the effect of continuous vibration and treatment with licorice root (Glycyrrhiza glabra L.) on peripheral blood red cells in rabbits. Active substances of licorice root accelerated metabolism in cells of the bone marrow erythroid stem, enhanced compensatory reserve of the organism, and increased animal's re...

journal_title：Bulletin of experimental biology and medicine

authors： Adamyan TI,Gevorkyan ES,Minasyan SM,Oganesyan KR,Kirakosyan KA

更新日期：2005-08-01 00:00:00

abstract：:Regeneratory activities of Baikal aconite alkaloids were studied on the excision skin wound model. Manifest wound healing effects of songorine, napelline, and hypaconitine were detected. The therapeutic efficiency was based on activation of residual mesenchymal progenitor elements. The development of this phenomenon w...

journal_title：Bulletin of experimental biology and medicine

authors： Zyuz'kov GN,Krapivin AV,Nesterova YV,Povetieva TN,Zhdanov VV,Suslov NI,Fomina TI,Udut EV,Miroshnichenko LA,Simanina EV,Semenov AA,Kravtsova SS,Dygai AM

更新日期：2012-10-01 00:00:00

abstract：:We studied the effect of electroconvulsive therapy on cognitive functions in rats with depression-like disorder caused by exposure to ultrasound of varying frequency (20-45 kHz). Object recognition and Morris water-maze tests revealed no negative effects of the therapy on memory. Moreover, positive effect of therapy w...

journal_title：Bulletin of experimental biology and medicine

authors： Ushakova VM,Zubkov EA,Morozova AY,Gorlova AV,Pavlov DA,Inozemtsev AN,Chekhonin VP

更新日期：2017-09-01 00:00:00

abstract：:We studied the effect of apolipoprotein A-I-tetrahydrocortisone complex on (14)C glucose absorption and lactate accumulation and on the rate of protein biosynthesis in isolated rat hepatocytes. The presence of apolipoprotein A-I-tetrahydrocortisone complex in the incubation medium increased absorption of labeled gluco...

journal_title：Bulletin of experimental biology and medicine

authors： Sumenkova DV,Knyazev RA,Guschya RS,Polyakov LM,Panin LE

更新日期：2009-08-01 00:00:00

abstract：:The risk of essential arterial hypertension was assessed in carriers of the NOS2 gene variants (rs1800482 (-954G>C), rs3730017 (C>T)). In subjects carrying C allele (rs1800482), the risk for essential arterial hypertension developing was higher by 1.7 times (OR=1.712, 95%CI 1.07-2.74), while the presence of T-allele (...

journal_title：Bulletin of experimental biology and medicine

authors： Topchieva LV,Balan OV,Korneeva VA,Malysheva IE

更新日期：2019-11-01 00:00:00

abstract：:We demonstrated the influence of short peptides on the expression of signaling molecules in organotypic culture of the pineal gland from 3-month-old rats. Peptides Ala-Glu-Asp-Gly and Lys-Glu-Asp stimulate the expression of proliferative protein Ki-67 in pineal gland culture. These peptides as well as Glu-Asp-Arg and ...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Linkova NS,Chalisova NI,Dudkov AV,Koncevaya EA

更新日期：2011-11-01 00:00:00

abstract：:The cytokine status (IFN, IL, etc.) of different monkey species (M. mulatta, P. hamadryas, C. aethiops) was studied. The interferon status is determined by the following parameters: IFN content in circulating blood and production of IFN-alpha and IFN-gamma by lymphocytes after appropriate in vitro induction. The inter...

journal_title：Bulletin of experimental biology and medicine

authors： Agrba VZ,Lapin BA,Mezentseva MV,Karal-ogly DD,Surgutcheva IM,Ignatova IE,Sherbenko VE,Agumava AA,Aphanasiev NA

更新日期：2009-08-01 00:00:00

abstract：:Phenibut and its derivatives normalized cellular (index of delayed-type hypersensitivity reaction) and humoral (antierythrocyte antibody titer) immunity and the lymphoproliferative processes in immunocompetent organs of animals with cyclophosphamide-induced immunosuppression. This indicates pronounced immunocorrective...

journal_title：Bulletin of experimental biology and medicine

authors： Tyurenkov IN,Samotrueva MA

更新日期：2009-05-01 00:00:00

abstract：:We compared the efficiency of different stereoisomers of organic magnesium salts (Mg DL-, Mg D-, and Mg L-aspartate and Mg L- and Mg DL-glutamate) after oral administration under conditions of furosemide-induced magnesium deficiency. The time to complete compensation of erythrocyte magnesium level was 5 days for Mg L-...

journal_title：Bulletin of experimental biology and medicine

authors： Spasov AA,Ozerov AA,Iezhitsa IN,Kharitonova MV,Kravchenko MS,Zheltova AA

更新日期：2011-07-01 00:00:00

abstract：:Cytochemical activity of succinate dehydrogenase and lactate dehydrogenase in blood lymphocytes, activity of hydroperoxides, MDA, and blood plasma antioxidants were studied in experimental animals during immobilization stress after preliminary injection of doxazosin. Preliminary adrenergic receptor blockade prevented ...

journal_title：Bulletin of experimental biology and medicine

authors： Vishnevskii EL,Vishnevskii AE,Shabel'nikova EI,Safronova ON,Dreval AA,Topchieva GV,Sukhorukov VS

更新日期：2004-11-01 00:00:00

abstract：:We studied expression of Flt-1 and Flk-1 receptors on tumor cells obtained from 83 patients with locally advanced breast cancer after neoadjuvant chemotherapy. The mean period of observations was 32.3 months. The median recurrence-free survival periods for Flt-1(+) and Flt-1(-) patients were 55 and 32 months, respecti...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova LG,Zhukov NV,Lichinitser MR

更新日期：2003-05-01 00:00:00