Electron-histochemical location of cathepsin D and elastase in the uterus.

abstract：:We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum i...

journal_title：Bulletin of experimental biology and medicine

authors： Aksenov DV,Kaplun VV,Tertov VV,Sobenin IA,Orekhov AN

更新日期：2007-01-01 00:00:00

abstract：:The distribution of polymorphic variants of innate immunity genes TLR9 (+2848G>A) and DEFB1(-20G>A; -44C>G; -52G>A) was evaluated in long-living individuals. No significant differences were found in the distribution of genotypes and alleles of the TLR9 gene. The following features were revealed: increase in the freque...

journal_title：Bulletin of experimental biology and medicine

authors： Gankovskaya LV,Svitich OA,Artem'eva OV,Miroshnichenkova AM,Rusanova KV

更新日期：2015-05-01 00:00:00

abstract：:The content of urokinase- and tissue-type plasminogen activators and plasminogen activator inhibitor PAI-1 in the cytosol of primary and metastatic melanomas and benign skin pigment neoplasms was estimated by enzyme immunoassay. It was shown that local growth and invasion of melanomas are related to suppressed express...

journal_title：Bulletin of experimental biology and medicine

authors： Gershtein ES,Medvedeva SV,Babkina IV,Kushlinskii NE,Trapeznikov NN

更新日期：2001-07-01 00:00:00

abstract：:The effects of cerivastatin on antiatherogenic properties of high-density lipoproteins were studied in patients with coronary heart disease and hyperlipidemia. Apart from hypolipidemic effects, cerivastatin changed the phospholipid composition of high-density lipoproteins and improved their cholesterol-acceptor proper...

journal_title：Bulletin of experimental biology and medicine

authors： Ozerova IN,Jeevan DM,Serdyuk AP,Paramonova IV,Akhmedzhanov NM,Metel'skaya VA,Perova NV

更新日期：2000-10-01 00:00:00

abstract：:We studied the effect of audiovisual stimulation training course on physical development, functional state of the cardiovascular system, blood biochemical parameters, and hormonal status of athletes. The training course led to improvement of physical performance and adaptive capacities of the circulatory system, incre...

journal_title：Bulletin of experimental biology and medicine

authors： Golovin MS,Golovin MS,Aizman RI

更新日期：2016-09-01 00:00:00

abstract：:The micronucleus test was used tu study the possibility of inducing cross-adaptive response in mouse bone marrow cells in vivo with an 850 nm infrared light modulated by a 101 Hz frequency, emitted by a light therapy device "Kurator". We demonstrated that this exposure led to a substantial reduction of cytogenetic cel...

journal_title：Bulletin of experimental biology and medicine

authors： Zaichkina SI,Rozanova OM,Dyukina AR,Akhmadieva AKh,Aptikaeva GF,Romanchenko SP,Muller X

更新日期：2009-04-01 00:00:00

abstract：:The effect of melanin solutions on the skin exposed to UV irradiation (1,050 kJ/m(2)) depended on its dose and varied from photoprotection (0.005 mg/ml) to photosensitization and phototoxicity (burn, 0.1 mg/ml). These results suggest that doses of melanin preparations should be empirically selected to achieve optimum ...

journal_title：Bulletin of experimental biology and medicine

authors： Paramonov BA,Turkovskii II,Potokin IL,Chebotarev VY

更新日期：2002-04-01 00:00:00

abstract：:Burn trauma increased blood chemiluminescence, while lipopolysaccharide in a dose of 1 mg/kg potentiated this effect, activated LPO, and decreased plasma antioxidant activity. In erythrocytes, superoxide dismutase activity increased, while activity of peroxide-utilizing enzymes decreased. Myeloperoxidase content incre...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhal'chik EV,Titkova SM,Anurov MV,Ettinger AP,Korkina LG

更新日期：2006-06-01 00:00:00

abstract：:Drug resistance and viability of Mycobacterium tuberculosis were studied in 637 patients with pulmonary tuberculosis, detected by screening fluorography (group 1) and in 909 patients in whom the specific process was detected when they applied for medical care (group 2). The mycobacteria in the two groups did not diffe...

journal_title：Bulletin of experimental biology and medicine

authors： Koretskaya NM,Narkevich AN

更新日期：2014-11-01 00:00:00

abstract：:We studied the effects of ionophores on activity of Na+,Cl-(HCO 3- )-ATPase. The most significant effect on the activity of this enzyme was produced by protonophore 2,4-dinitrophenol. The effect of this drug largely depended on the cation and anion composition and pH of the incubation medium and its pH. Activity of Na...

journal_title：Bulletin of experimental biology and medicine

authors： Yurkiv VA,Melikhov VI,Shubin VS

更新日期：2016-10-01 00:00:00

abstract：:The epileptogenic effects of applications of NMDA and kainic acid solutions to the frontal cortex were attenuated in rats receiving ketogenic diet (80% lipids, 3.3% carbohydrates, and 16.7% proteins) during 4 weeks. Spike latency increased, the power of focal epileptic activity decreased, and focus lifetime was shorte...

journal_title：Bulletin of experimental biology and medicine

authors： Kresyun VI,Polyasny VA,Godovan VV,Godlevsky LS

更新日期：2013-02-01 00:00:00

abstract：:We studied etiologic structure of bacterial intestinal infections in monkeys of Adler nursery. A total of 533 monkeys with diarrhea syndrome and monkeys dead from intestinal infections, as well as clinically healthy monkeys and animals dead from other pathologies were examined by bacteriological and molecular-genetic ...

journal_title：Bulletin of experimental biology and medicine

authors： Ardasheliya SN,Kalashnikova VA,Dzhikidze EK

更新日期：2011-10-01 00:00:00

abstract：:Transcription profiles of genes of local immune response were determined in the vagina of women with bacterial vaginosis, aerobic vaginitis, and vulvovaginal candidosis for detection of the most specific immune markers for these vaginal infections. Laboratory diagnosis of the vaginal infections was performed microscop...

journal_title：Bulletin of experimental biology and medicine

authors： Budilovskaya OV,Shipitsina EV,Spasibova EV,Pereverzeva NA,Vorob'eva NE,Tsypurdeeva ND,Grigoryev AN,Savicheva AM

更新日期：2020-03-01 00:00:00

abstract：:We studied the effects of lithium carbonate on the cell cycle, apoptosis, and autophagy in hepatocellular carcinoma-29 cells (HCC-29) in vitro. Flow cytofluorometry analysis revealed accumulation of G2/M-phase HCC-29 cells and increase in the number of apoptotic cells in 48 h after administration of 5 mM lithium carbo...

journal_title：Bulletin of experimental biology and medicine

authors： Taskaeva YS,Bgatova NP,Dossymbekova RS,Solovieva AO,Miroshnichenko SM,Sharipov KO,Tungushbaeva ZB

更新日期：2020-12-01 00:00:00

abstract：:Plasma cytokine concentration in patients with Parkinson's disease and mutation in GBA gene, in patients with sporadic Parkinson's disease, and in healthy volunteers were measured by ELISA and multiplex analysis. In patients with Parkinson's disease and mutation in GBA gene, elevated plasma concentrations of IL-1β and...

journal_title：Bulletin of experimental biology and medicine

authors： Miliukhina IV,Usenko TS,Senkevich KA,Nikolaev MA,Timofeeva AA,Agapova EA,Semenov AV,Lubimova NE,Totolyan AA,Pchelina SN

更新日期：2020-02-01 00:00:00

abstract：:The C-terminal fragment Pro-Gly-Pro of semax does not modulate the development of symptoms of neurological deficiency and mortality in rats with incomplete global cerebral ischemia. Hence, previously revealed neuroprotective effects of semax are mainly determined by corticotropin ACTH4-7 fragment. ...

journal_title：Bulletin of experimental biology and medicine

authors： Fadyukova OE,Kadi A,Bai O,Andzhusheva GM,Koshelev VB

更新日期：2005-04-01 00:00:00

abstract：:Trekrezan in a dose of 25 mg/kg normalized the lymphocyte immune status and produced an energy-stabilizing effect, which manifested in decreased levels of lactate, ADP, and AMP and increased content of pyruvate and ATP in blood lymphocytes and lung tissue of rats with experimental acute bronchopneumonia. ...

journal_title：Bulletin of experimental biology and medicine

authors： Zarubina IV,Bolekhan AV,Shabanov PD

更新日期：2006-08-01 00:00:00

abstract：:Experiments on the model of mouse BCG-induced granulomatous showed that the content of glycosaminoglycans and proteoglycans in the extracellular matrix of the liver and lungs are changed at the early stages of inflammation (days 3 and 30 postinfection) before cell destruction in the organs begins. This is related to d...

journal_title：Bulletin of experimental biology and medicine

authors： Kim LB,Shkurupy VA,Putyatina AN

更新日期：2015-01-01 00:00:00

abstract：:Regeneratory activities of Baikal aconite alkaloids were studied on the excision skin wound model. Manifest wound healing effects of songorine, napelline, and hypaconitine were detected. The therapeutic efficiency was based on activation of residual mesenchymal progenitor elements. The development of this phenomenon w...

journal_title：Bulletin of experimental biology and medicine

authors： Zyuz'kov GN,Krapivin AV,Nesterova YV,Povetieva TN,Zhdanov VV,Suslov NI,Fomina TI,Udut EV,Miroshnichenko LA,Simanina EV,Semenov AA,Kravtsova SS,Dygai AM

更新日期：2012-10-01 00:00:00

abstract：:Application of anxiolytic drug Selank to hippocampal slices increased the amplitude and discharge rate of spontaneous inhibitory postsynaptic currents in rat hippocampal pyramidal CA1 neurons. In some neurons, Selank-induced up-regulation of spontaneous inhibitory postsynaptic currents was preceded by a transient decr...

journal_title：Bulletin of experimental biology and medicine

authors： Povarov IS,Kondratenko RV,Derevyagin VI,Myasoedov NF,Skrebitsky VG

更新日期：2017-03-01 00:00:00

abstract：:We demonstrated the influence of short peptides on the expression of signaling molecules in organotypic culture of the pineal gland from 3-month-old rats. Peptides Ala-Glu-Asp-Gly and Lys-Glu-Asp stimulate the expression of proliferative protein Ki-67 in pineal gland culture. These peptides as well as Glu-Asp-Arg and ...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Linkova NS,Chalisova NI,Dudkov AV,Koncevaya EA

更新日期：2011-11-01 00:00:00

abstract：:The inotropic response of the myocardium to extrasystolic treatment was studied on isolated perfused papillary muscles from rats with postinfarction cardiosclerosis. The development of postinfarction cardiosclerosis was accompanied by a decrease in myocardial excitability. The amplitude of extrasystolic contractions i...

journal_title：Bulletin of experimental biology and medicine

authors： Kondrat'eva DS,Afanas'ev SA,Falaleeva LP,Shakhov VP

更新日期：2005-06-01 00:00:00

abstract：:An important role in the development of the immune response is played by macrophages that acquire either anti-inflammatory M1 or anti-inflammatory M2 phenotype depending on their microenvironment. The possibility of targeted reprogramming of the initial M2 macrophage phenotype towards M1 phenotype and vice versa using...

journal_title：Bulletin of experimental biology and medicine

authors： Lyamina SV,Kruglov SV,Vedenikin TY,Borodovitsyna OA,Suvorova IA,Shimshelashvili ShL,Malyshev IY

更新日期：2012-02-01 00:00:00

abstract：:The cell composition of leukocyte infiltrates in the endometrium, myometrium, and vaginal walls was studied in Wistar rats with modeled chronic endomyometritis after administration of IFNγ (0.1 μg/100 g body weight) in different daily regimens (10.00 or 20.00). Morning injections of this cytokine ameliorated inflammat...

journal_title：Bulletin of experimental biology and medicine

authors： Dergacheva TI,Shurlygina AV,Abdalova AM,Klimontov VV,Trufakin VA,Letyagin AY

更新日期：2020-08-01 00:00:00

abstract：:We studied the interaction of neural stem cells and dental pulp-derived mesenchymal stem cells with lymphocytes from autologous and heterologous donors. Flow cytometry analysis with the use of CFSE-labeled lymphocytes demonstrated an increase in the content of proliferating CD8, CD16 and CD56 cells, but not CD4 cells ...

journal_title：Bulletin of experimental biology and medicine

authors： Svirshchevskaya EV,Poltavtseva RA,Beletskii IP,Selezneva II,Savilova AM,Sukhikh GT

更新日期：2016-08-01 00:00:00

abstract：:Blood flow in reproductive organs was studied during experimental cessation of blood outflow in the testicular vein. This pathological state was accompanied by disturbances of the complex pathogenesis. The major component was autoregulatory focal ischemia, which resulted from the venoarterial response to venous hypert...

journal_title：Bulletin of experimental biology and medicine

authors： Artifeksov SB,Artyukhin AA

更新日期：2007-06-01 00:00:00

abstract：:Paclitaxel in a single MTD of 40 mg/kg caused chromosome aberrations and genome changes (polyploidy) in the bone marrow cells of mice early and 3 months after the injection. The quantity of early precursors of erythropoiesis in the bone marrow decreased, as did their proliferative potential irrespective of the animal ...

journal_title：Bulletin of experimental biology and medicine

authors： Neupokoeva OV,Fedorova EP,Stavrova LA,Voronova OL,Sandrikina LA,Filonova MV,Churin AA

更新日期：2020-05-01 00:00:00

abstract：:Viability of keratinocytes of HaCaT immortalized line incubated with sodium dodecyl sulfate for 3 min, 1 and 48 h, was studied by light microscopy, MTT test, and neutral red absorption test. The IC50 values were determined for each of the studied lengths of exposure. HaCaT cells exhibited a dose-dependent decrease of ...

journal_title：Bulletin of experimental biology and medicine

authors： Rusanov AL,Luzgina NG,Lisitsa AV

更新日期：2017-06-01 00:00:00

abstract：:We studied properties of cloned BACE mRNA (beta-site of the enzyme cleaving amyloid precursor protein) and evaluated the possibility of using this clone for identification and/or prediction of neurodegenerative disorders associated with cholinergic deficiency. Wistar rats subjected to immunohistochemical destruction o...

journal_title：Bulletin of experimental biology and medicine

authors： Lushchekina EA,Bigl M,Apelt J,Lange-Dohna C,Rossner S,Schliebs R

更新日期：2002-09-01 00:00:00

abstract：:Oxidized dextran is suggested for prevention of infection induced by influenza A/H5N1 viruses, methods of its use and doses are determined. Two intravenous injections of dextran 3 and 1 days before experimental infection of outbred mice by influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus resulted in a high preven...

journal_title：Bulletin of experimental biology and medicine

authors： Shkurupy VA,Potapova OV,Sharkova TV,Troitskii AV,Gulyaeva EP,Bystrova TN,Shestopalov AM

更新日期：2014-11-01 00:00:00