Effect of plant extracts on trans-sialidase activity in human blood plasma.

Abstract:

:We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum inhibitory effect. trans-Sialidase activity of blood plasma ex vivo decreased 2-fold after peroral administration of pollen and garlic powder. A correlation was found between the decrease in trans-sialidase activity in blood plasma and ability of blood plasma to induce cholesterol accumulation in cultured cells from the intact human aortic intima.

journal_name

Bull Exp Biol Med

authors

Aksenov DV,Kaplun VV,Tertov VV,Sobenin IA,Orekhov AN

doi

10.1007/s10517-007-0013-2

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

46-50

issue

1

eissn

0007-4888

issn

1573-8221

journal_volume

143

pub_type

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