Effect of Coenzyme Q10 on Expression of UbiAd1 Gene in Rat Model of Local Cerebral Ischemia.

abstract：:In biopsy specimens of the gastric and duodenal mucosa from patients with psoriasis we revealed severe degenerative and dystrophic changes in cells of the surface and glandular epithelium with destruction of functionally important cytoplasmic organelles. The stroma of the gastric mucosa was characterized by hyperplasi...

journal_title：Bulletin of experimental biology and medicine

authors： Khardikova SA,Nepomnyashchikh GI,Aidagulova SV,Lapii GA

更新日期：2002-11-01 00:00:00

abstract：:Oxidized dextran is suggested for prevention of infection induced by influenza A/H5N1 viruses, methods of its use and doses are determined. Two intravenous injections of dextran 3 and 1 days before experimental infection of outbred mice by influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus resulted in a high preven...

journal_title：Bulletin of experimental biology and medicine

authors： Shkurupy VA,Potapova OV,Sharkova TV,Troitskii AV,Gulyaeva EP,Bystrova TN,Shestopalov AM

更新日期：2014-11-01 00:00:00

abstract：:We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Naumova LA,Osipova ON,Klinnikova MG

更新日期：2019-04-01 00:00:00

abstract：:Secretion of chemokines under different conditions of monocyte and endothelial cell coculturing was compared. Secretion of all the studied chemokines was recorded in cocultures: IL-8/CXCL-8, MCP-1/CCL2, RANTES/CCL5, and IP-10/CXCL10. The presence of TNF-α increased the concentrations of all chemokines, the concentrati...

journal_title：Bulletin of experimental biology and medicine

authors： Starickova EA,Sokolov DI,Selkov SA,Freidlin IS

更新日期：2011-02-01 00:00:00

abstract：:A new universal method for measuring activity of the serum complement system in humans, laboratory, domestic, agricultural animals, birds and amphibians is based on automated evaluation of the mortality of ciliate Tetrahymena pyriformis under the effect of the complement system. In contrast to the hemolytic method, me...

journal_title：Bulletin of experimental biology and medicine

authors： Kuleshina ON,Kozlov LV,Cheremnykh EG

更新日期：2014-06-01 00:00:00

abstract：:We studied the effects of calcitonin, parathyrin, and Ca(2+) channel antagonist isoptin and agonist Bay-K-8644 on glucose consumption by muscle (diaphragm) and adipose (epididymal) tissues and insulin-stimulated glucose consumption in vivo and in vitro. Calcitonin and parathyrin did not alter glucose consumption; para...

journal_title：Bulletin of experimental biology and medicine

authors： Butakova SS,Nozdrachev AD

更新日期：2009-08-01 00:00:00

abstract：:Experiments on stationary culture of posterior eye and roll-bottle culture of the whole eye from adult water lizards Pleurodeles waltl showed that sclera bioregulator produces a stabilizing effects on adhesion interactions between the sclera, choroid, and pigment epithelium and on the maintenance of viability of scler...

journal_title：Bulletin of experimental biology and medicine

authors： Yamskova VP,Krasnov MS,Skripnikova VS,Yamskov IA

更新日期：2010-10-01 00:00:00

abstract：:No appreciable disorders of cellular immunity were detected in patients with glandular cystic endometrial hyperplasia. Atypical endometrial hyperplasia was associated with quantitative changes in T lymphocytes and their subpopulations, decreased level of lymphocytes carrying activation antigens, and increased count of...

journal_title：Bulletin of experimental biology and medicine

authors： Lysenko ON,Strizhova NV,Kholodova ZhL

更新日期：2003-01-01 00:00:00

abstract：:Viability of keratinocytes of HaCaT immortalized line incubated with sodium dodecyl sulfate for 3 min, 1 and 48 h, was studied by light microscopy, MTT test, and neutral red absorption test. The IC50 values were determined for each of the studied lengths of exposure. HaCaT cells exhibited a dose-dependent decrease of ...

journal_title：Bulletin of experimental biology and medicine

authors： Rusanov AL,Luzgina NG,Lisitsa AV

更新日期：2017-06-01 00:00:00

abstract：:The cytokine status (IFN, IL, etc.) of different monkey species (M. mulatta, P. hamadryas, C. aethiops) was studied. The interferon status is determined by the following parameters: IFN content in circulating blood and production of IFN-alpha and IFN-gamma by lymphocytes after appropriate in vitro induction. The inter...

journal_title：Bulletin of experimental biology and medicine

authors： Agrba VZ,Lapin BA,Mezentseva MV,Karal-ogly DD,Surgutcheva IM,Ignatova IE,Sherbenko VE,Agumava AA,Aphanasiev NA

更新日期：2009-08-01 00:00:00

abstract：:Structural characteristics of the adrenal medulla in hypertensive NISAG rats (hereditary stress-induced arterial hypertension) were studied during various periods of postnatal ontogeny. Signs of hyperplasia of the adrenal medulla were most pronounced in adult hypertensive animals with persistent arterial hypertension,...

journal_title：Bulletin of experimental biology and medicine

authors： Buzueva II,Filyushina EE,Shmerling MD,Markel AL,Yakobson GS

更新日期：2006-12-01 00:00:00

abstract：:Thromboelastography revealed anticoagulant effects of 3 glyproline oligopeptides (in various concentrations): His-Phe-Arg-Trp-Pro-Gly-Pro, Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selank), and Pro-Gly-Pro. The parameters R, K, MA, S, TMA, and J changed to hypocoagulation direction in comparison to the control. At this, Selank dem...

journal_title：Bulletin of experimental biology and medicine

authors： Rogozinskaya EY,Lyapina MG

更新日期：2017-12-01 00:00:00

abstract：:Immunization of mice with synthetic peptide fragments of conservative sites of meningococcal outer membrane proteins led to defense formation against infection with virulent serogroup A and B Meningococci. The role of cellular immunity in the formation of defense against meningococcal infection after immunization with...

journal_title：Bulletin of experimental biology and medicine

authors： Chibiskova OV,Kotel'nikova OV,Nesmeyanov VA,Alliluev AP,Vol'pina OM,Koroev DO,Filatova MP

更新日期：2007-06-01 00:00:00

abstract：:We demonstrated the influence of short peptides on the expression of signaling molecules in organotypic culture of the pineal gland from 3-month-old rats. Peptides Ala-Glu-Asp-Gly and Lys-Glu-Asp stimulate the expression of proliferative protein Ki-67 in pineal gland culture. These peptides as well as Glu-Asp-Arg and ...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Linkova NS,Chalisova NI,Dudkov AV,Koncevaya EA

更新日期：2011-11-01 00:00:00

abstract：:During exacerbation of cytomegalovirus infection during pregnancy, cytomegalovirus proteins penetrate across the external membrane of placental villous syncytiotrophoblast and suppress activities of ATPase and Bcl-2 protein. Simultaneous increase in the content of annexin V and caspase 3 leads to structural disturbanc...

journal_title：Bulletin of experimental biology and medicine

authors： Lutsenko MT,Andrievskaya IA

更新日期：2016-01-01 00:00:00

abstract：:Biopsy specimens from large bronchi of patients with central and peripheral pulmonary cancer were studied. Central cancer was associated with hyperplasia and dysplasia of the epithelium, hyperplasia of glandular compartment, and pronounced immunocompetent cell response. Peripheral cancer was characterized by predomina...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh GI,Levitskii VA,Dolgovykh AK,Naumova LA

更新日期：2002-08-01 00:00:00

abstract：:We studied the role of ryanodine receptors in the effects of hydrogen sulfide on transmitter release from frog motor nerve ending. Sodium hydrosulfide (300 μM), a donor of hydrogen sulfide, reversibly increased the frequency of miniature endplate current without changes in its amplitude-time parameters. These effects ...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimova EV,Yakovleva OV,Zefirov AL,Sitdikova GF

更新日期：2013-05-01 00:00:00

abstract：:We studied the neuroprotective effect of a new selective anxiolytic afobazole on rats with bilateral focal ischemic stroke in the prefrontal cortex caused by photothrombosis. Intraperitoneal injection of 5 mg/kg afobazole 1 h after surgery and over the next 8 days (daily treatment) produced a neuroprotective effect. A...

journal_title：Bulletin of experimental biology and medicine

authors： Seredenin SB,Romanova GA,Shakova FM

更新日期：2008-02-01 00:00:00

abstract：:Melatonin administered to intact animals increased glutathione concentration and activities of glutathione peroxidase, glutathione reductase, NADP-isocitrate dehydrogenase, and glucose-6-phosphate dehydrogenase in the liver. In animals with toxic hepatitis melatonin treatment decreased glutathione concentration and en...

journal_title：Bulletin of experimental biology and medicine

authors： Pashkov AN,Popov SS,Semenikhina AV,Rakhmanova TI

更新日期：2005-05-01 00:00:00

abstract：:The study examined maturation of preovulatory germinal vesicles oocytes (GV oocytes) induced by gonadotropic hormone PMSG in the inbred C57Bl/6J mice (viewed as a gold standard for diverse biomedical studies) as well as in the first generation hybrid C57Bl/6J×СВА/lac and СВА/lac×C57Bl/6J mice at various ages. The most...

journal_title：Bulletin of experimental biology and medicine

authors： Riabukha YA,Petrova DA,Zatsepina OV

更新日期：2019-09-01 00:00:00

abstract：:Autooxidation of low-density lipoproteins during incubation at 37 degrees C was accompanied by accumulation of LPO products, decrease in UV autofluorescence (FUV), and increase in autofluorescence in the visible band (FVIS). The degree of low-density lipoprotein modification was estimated by calculating the FVIS/FUV r...

journal_title：Bulletin of experimental biology and medicine

authors： Aidyraliev RK,Azizova OA,Vakhrusheva TV,Lopukhin YM,Mirrakhimov MM

更新日期：2006-10-01 00:00:00

abstract：:The expression of synaptophysin (vesicular protein) and mGluR5 (metabotropic glutamate receptor) genes was studied 3, 7, and 20 days after cainic acid injury of the dorsal hippocampal area in Wistar rats. The expression of both genes was characteristically reduced in the hippocampus. Twenty days after the exposure the...

journal_title：Bulletin of experimental biology and medicine

authors： Lebedev DS,Arkhipov VI

更新日期：2009-02-01 00:00:00

abstract：:The risk of essential arterial hypertension was assessed in carriers of the NOS2 gene variants (rs1800482 (-954G>C), rs3730017 (C>T)). In subjects carrying C allele (rs1800482), the risk for essential arterial hypertension developing was higher by 1.7 times (OR=1.712, 95%CI 1.07-2.74), while the presence of T-allele (...

journal_title：Bulletin of experimental biology and medicine

authors： Topchieva LV,Balan OV,Korneeva VA,Malysheva IE

更新日期：2019-11-01 00:00:00

abstract：:The efficiency of drug therapy should be evaluated by not only its directed action on specific organ or target parameter, but also its effects on general regulatory and adaptive status. ...

journal_title：Bulletin of experimental biology and medicine

authors： Pokrovskii VM,Kompaniets OG

更新日期：2008-06-01 00:00:00

abstract：:Transplantation of human bone marrow mesenchymal stem cells is considered as a promising therapeutic approach to the therapy of many diseases. However, the problem of possible alterations of the properties of mesenchymal stem cells during their expansion in in vitro cultures before transplantation is not solved. In ou...

journal_title：Bulletin of experimental biology and medicine

authors： Grigorian AS,Kruglyakov PV,Taminkina UA,Efimova OA,Pendina AA,Voskresenskaya AV,Kuznetsova TV,Polyntsev DG

更新日期：2010-12-01 00:00:00

abstract：:Regeneratory activities of Baikal aconite alkaloids were studied on the excision skin wound model. Manifest wound healing effects of songorine, napelline, and hypaconitine were detected. The therapeutic efficiency was based on activation of residual mesenchymal progenitor elements. The development of this phenomenon w...

journal_title：Bulletin of experimental biology and medicine

authors： Zyuz'kov GN,Krapivin AV,Nesterova YV,Povetieva TN,Zhdanov VV,Suslov NI,Fomina TI,Udut EV,Miroshnichenko LA,Simanina EV,Semenov AA,Kravtsova SS,Dygai AM

更新日期：2012-10-01 00:00:00

abstract：:Newborn rats received intraperitoneal injections of endothelin-1 in a daily dose of 5 x 10(-8)mol/kg 30 min after administration of NG-nitro-L-arginine methyl ester (9.3 x 10(-5)mol/kg intraperitoneally) from the 2nd to 6th day of life. NADPH diaphorase activity in epithelial and smooth muscle cells of the tracheobron...

journal_title：Bulletin of experimental biology and medicine

authors： Lebed'ko OA,Timoshin SS,Tsygankov VI

更新日期：2002-03-01 00:00:00

abstract：:We analyzed the expression of galectin-1 and galectin-3 in tumor tissue in stomach and colorectal cancer with and without tissue eosinophilia. Low expression of galectin-3 was detected in all patients with malignant gastrointestinal tumors irrespective of the presence of eosinophilia. Low expression of galectin-1 was ...

journal_title：Bulletin of experimental biology and medicine

authors： Kolobovnikova YV,Dmitrieva AI,Yankovich KI,Vasil'eva OA,Purlik IL,Poletika VS,Novitskii VV,Urazova OI

更新日期：2018-06-01 00:00:00

abstract：:Polymorphic variants of CYP1A2 and CYP2D6 genes of the cytochrome P450 system were studied in patients with schizophrenia with drug-induced motor disorders and hyperprolactinemia against the background of long-term neuroleptic therapy. We revealed an association of polymorphic variant C-163A CYP1A2*1F of CYP1A2 gene w...

journal_title：Bulletin of experimental biology and medicine

authors： Ivanova SA,Filipenko ML,Vyalova NM,Voronina EN,Pozhidaev IV,Osmanova DZ,Ivanov MV,Fedorenko OY,Semke AV,Bokhan NA

更新日期：2016-03-01 00:00:00

abstract：:Burn trauma increased blood chemiluminescence, while lipopolysaccharide in a dose of 1 mg/kg potentiated this effect, activated LPO, and decreased plasma antioxidant activity. In erythrocytes, superoxide dismutase activity increased, while activity of peroxide-utilizing enzymes decreased. Myeloperoxidase content incre...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhal'chik EV,Titkova SM,Anurov MV,Ettinger AP,Korkina LG

更新日期：2006-06-01 00:00:00