Abstract:
:o-Aminoazotoluene in noncarcinogenic doses promoted the development of liver tumors in female ICR mice induced by administration of diethylnitrosamine during early ontogeny. Severe inflammatory infiltration and proliferation of oval cells were found in liver tissue of these animals. The concentration of free thyroxin decreased in the blood. Our results supplement published data that promoters of hepatocarcinogenesis inhibit thyroid function.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Baginskaya NV,Il'nitskaya SI,Nikitenko EV,Kaledin VIdoi
10.1007/s10517-007-0440-0subject
Has Abstractpub_date
2007-12-01 00:00:00pages
821-4issue
6eissn
0007-4888issn
1573-8221journal_volume
144pub_type
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