Abstract:
:The number of CD3(+)CD56-HLA-G(+) cells in the peripheral blood of breast cancer patients was shown to increase by 2 times. Our results and published data suggest that the increase in the relative content of CD3(+)CD56-HLA-G(+) cells in the circulating blood in breast cancer contributes to tumor development due to suppression of antitumor immunity.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Ostapchuk EO,Perfi L'eva YV,Talaeva ShZh,Omarbaeva NA,Belyaev NNdoi
10.1007/s10517-015-3038-ysubject
Has Abstractpub_date
2015-09-01 00:00:00pages
649-51issue
5eissn
0007-4888issn
1573-8221pii
10.1007/s10517-015-3038-yjournal_volume
159pub_type
杂志文章abstract::We studied reflection of artificially induced and amplified food motivation in impulse activity of the masticatory muscles during electrostimulation of "hunger center" of the lateral hypothalamus in the absence and presence of food. The threshold stimulation of the lateral hypothalamus in hungry and satiated animals i...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-012-1602-2
更新日期:2012-04-01 00:00:00
abstract::The animals were adapted to intermittent hypoxic hypoxia in a flow pressure chamber for 3 days. Each one-day training session consisted of 4 elevations to an altitude of 6000 m for 20 min (15 m/sec, 20-min intervals between assents). Trekrezan (25 mg/kg intraperitoneally) was injected immediately after the end of dail...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-008-0010-0
更新日期:2008-01-01 00:00:00
abstract::A composition containing culture medium conditioned by mesenchymal stem cells and mesenchymal stem cell lysate improves biochemical parameters, reduces inflammation, and stimulates regenerative processes in the liver. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-015-2905-x
更新日期:2015-05-01 00:00:00
abstract::We studied the effect of audiovisual stimulation training course on physical development, functional state of the cardiovascular system, blood biochemical parameters, and hormonal status of athletes. The training course led to improvement of physical performance and adaptive capacities of the circulatory system, incre...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-016-3474-3
更新日期:2016-09-01 00:00:00
abstract::The data of genome-wide association analysis suggest that human 6p21.3 chromosomal region (localization of HLA genes) contains polymorphic loci influencing the risk of developing non-Hodgkin's lymphomas. We analyzed association of rs2647012 and rs805288 loci with the risk for non-Hodgkin's malignant lymphomas in the p...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2520-2
更新日期:2014-06-01 00:00:00
abstract::Organized activity of the myocardium manifested in dominant frequency structure of EСG was typical of the first 10 min of ventricular fibrillation in canine heart. The first minute of fibrillation was characterized by the most pronounced changes in the structure of oscillation frequency and transition from domination ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-016-3153-4
更新日期:2016-01-01 00:00:00
abstract::Polylactide degradation processes after its implantation into the subcutaneous fat of rats were studied by microscopy. After implantation polylactide was encapsulated in connective tissue. If a fragment of polylactide had sharp edges, injuring the tissue, a thick capsule formed with pronounced inflammatory infiltratio...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2473-5
更新日期:2014-04-01 00:00:00
abstract::Interleukin-1beta mRNA, interleukin-1beta receptor mRNA, and erythropoietin receptor mRNA are expressed in the brain of (CBAxC57Bl)F1 mice. Immunization with sheep erythrocytes stimulated the expression of these cytokines in the cerebral hemispheres. Injection of recombinant erythropoietin reduced expression of interl...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1015112729103
更新日期:2002-01-01 00:00:00
abstract::Morphometric analysis of structural and functional changes in the human mesenteric lymph nodes during aging revealed the development of fibrous connective tissue, fragmentation of the lymphoid parenchyma, the absence of follicles with germinal centers, and a decrease in the level of lymphocyte proliferation, which was...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04782-0
更新日期:2020-03-01 00:00:00
abstract::We studied mesenchymal stem cells from human bone marrow, adipose tissue, skin, placenta, and thymus. Morphological study and cytofluorometrical analysis by the main marker genes (CD10, CD13, CD31, CD44, CD90, CD105) were carried out. Mesemchymal stem cells of the studied tissues during isolation and culturing were mo...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0331-1
更新日期:2005-04-01 00:00:00
abstract::Presentation of visual and acoustic stimuli at a rate of 2-30 Hz modulated variability of the heart rhythm in volunteers. Potentation of vagal influences and a decrease in the contribution of ergotropic systems to the regulation of the heart rate were noted after 10 sessions of audiovisual stimulation. These changes w...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1017667903060
更新日期:2001-03-01 00:00:00
abstract::Blood levels of stem cell marker proteins CD34 and osteonectin were studied in male patients with coronary atherosclerosis by direct biomagnetic separation of proteins with magnetic microspheres using the PureProteome Protein A and Protein G Magnetic Beads proteomic technology. High concentration of osteonectin in the...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1333-9
更新日期:2011-07-01 00:00:00
abstract::We studied reactions of the granulocytic hemopoietic stem during hypoxia of different genesis and severity. Stimulation of granulocytopoiesis was determined by an increase in functional activity of granulomonocytic precursors due to changes in feeder capacity of cells in the hemopoiesis-inducing microenvironment and c...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0271-9
更新日期:2005-03-01 00:00:00
abstract::Calmodulin inhibitor W-7 did not cause changes in the quantal content of postsynaptic end-plate potentials (EPP) in newly formed synapses, but prevented facilitation of acetylcholine secretion induced by L-type Ca(2+)channels blocker nitrendipine. CaMKII inhibitor KN-62 produced similar effect and suppressed the incre...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-013-1940-8
更新日期:2013-01-01 00:00:00
abstract::Here we review the mechanisms underlying systemic regulation of the genome in brain nerve cells. Expression of early and late behavioral genes is regulated by systemic processes in dominant functional systems. The main elements of this molecular and genetic cascade are similar during learning and development. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章,评审
doi:10.1023/a:1023843125404
更新日期:2003-02-01 00:00:00
abstract::Preliminary injection of succinic semialdehyde into animals in experiments with hypoxia led to a lower concentration of free ammonia in their brain tissues than in control experiments in which the compound was not given. The enzyme system of the liver tissue catalyzes the oxidation of NAD-H-2 by succinic semialdeyde a...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/BF00799318
更新日期:1975-01-01 00:00:00
abstract::Experiments on the model of an aggressive-conflict situation were designed to study the effect of emotional stress on biogenic amine content in the sensorimotor cortex of the right cerebral hemisphere in behaviorally active and passive rats with experimental hemorrhage in the left caudate nucleus of the brain. Prior e...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-013-1966-y
更新日期:2013-02-01 00:00:00
abstract::Differential expression of type 1 cannabinoid receptors (CR1) was evaluated at different stages of human skin fibroblast transformation into terminally differentiated neurons. Immunocytochemical staining detected no CR1 on fibroblasts, but their transformation into induced pluripotent stem cells was accompanied by mar...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-017-3782-2
更新日期:2017-06-01 00:00:00
abstract::We studied the specific features of ultrasonic vocalization of Wistar rats in various motivational and emotional states. No significant changes were found in ultrasonic vocalization of rats during experimental food motivation and after the satisfaction of food requirements. The state of thirst and satisfaction of wate...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-012-1831-4
更新日期:2012-10-01 00:00:00
abstract::The formation of an ischemic focus in the myocardium is paralleled by autoimmune processes involving immunoglobulins with abnormal thermal solubility, cryoglobulins. Serum levels of cryoglobulins and their complexes were measured in 25 patients with Q-forming myocardial infarction on days 1, 2, 3, 7, and 14 of the dis...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1155-9
更新日期:2011-02-01 00:00:00
abstract::Studies of the effects of Trichoderma harzianum Rifai F-180 culture fluid concentrate containing L-lysine-α-oxidase antitumor enzyme produced by the fungus and the homogenous enzyme, on ultrahazardous bacterium Acidovorax citrulli demonstrated the antibacterial activity of the concentrate. Trichoderma harzianum Rifai ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-018-4012-2
更新日期:2018-03-01 00:00:00
abstract::An important role in the development of the immune response is played by macrophages that acquire either anti-inflammatory M1 or anti-inflammatory M2 phenotype depending on their microenvironment. The possibility of targeted reprogramming of the initial M2 macrophage phenotype towards M1 phenotype and vice versa using...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-012-1572-4
更新日期:2012-02-01 00:00:00
abstract::We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-019-04438-8
更新日期:2019-04-01 00:00:00
abstract::The effects of intramuscular administration of neostigmine and physostigmine on Na+,K+-ATPase activity in various cerebral subdivisions were examined in rats. In CNS and peripheral tissues, both agents rapidly and significantly reduced activity of cholinesterases by 30-50%. The development of intoxication did not chan...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-018-4287-3
更新日期:2018-11-01 00:00:00
abstract::Model experiments on biomicroscopy of mesenteric microvessels in laboratory rats were performed to evaluate the effect of natural metabolites (e.g., amino acid glycine) on the microcirculation. The effect of glycine was determined from a change in the diameter of arterioles. Application of glycine (0.1 ml, 1 M) to the...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-009-0498-y
更新日期:2009-03-01 00:00:00
abstract::Olivomycin (DNA-binding antibiotic) in nanomolar concentrations induces apoptosis of human tumor cells and inhibits p53-dependent transcription of the reporter gene (basal and induced by antitumor drugs). Olivomycin aglycon induces no cytotoxicity and does not block transcription. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0321-3
更新日期:2005-04-01 00:00:00
abstract::Effect of afobazole on the threshold of electrical fibrillation of the heart was studied on anesthetized rats with intact myocardium. It was shown that the drug considerably increased the threshold of electrical fibrillation of the heart, being not inferior to reference class I antiarrhythmic drugs (lidocaine and proc...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-010-0935-y
更新日期:2010-09-01 00:00:00
abstract::"Therapeutic Effects of Salidroside on Cognitive Ability in Rats with Experimental Vascular Dementia," by Z. Tian, Yu. Li, G. Wang, J. Wang, and Ye. Zhang, Vol. 169, No. 1, pp. 35-39, May 2020. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10517-020-04872-z
更新日期:2020-06-01 00:00:00
abstract::Effects of Miramistin and Phosprenil on biofilms of S. pyogenes, S. aureus, E. coli, L. acidophilus, and L. plantarum were studied. Significant differences in the effects of these substances on mature biofilms of microorganisms and the process of their formation were observed. Miramistin had significant inhibiting eff...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-017-3823-x
更新日期:2017-08-01 00:00:00
abstract::We studied the effect of vasopressin analogue desglycinamide-arginine-vasopressin on changes in platelet hemostasis produced by intragastric administration of Ticlid or clopidogrel (inhibitors of ADP-induced platelet aggregation). Intranasal administration of the peptide under conditions of hemorrhagic diathesis produ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0434-8
更新日期:2005-08-01 00:00:00