Cytokine gene expression in cerebral hemispheres and behavioral reactions of (CBAxC57Bl)F1 mice.

Abstract:

:Interleukin-1beta mRNA, interleukin-1beta receptor mRNA, and erythropoietin receptor mRNA are expressed in the brain of (CBAxC57Bl)F1 mice. Immunization with sheep erythrocytes stimulated the expression of these cytokines in the cerebral hemispheres. Injection of recombinant erythropoietin reduced expression of interleukin-1beta, interleukin-1beta receptor, and erythropoietin receptor genes in the brain of experimental animals and considerably increased their motor activity in the open field test.

journal_name

Bull Exp Biol Med

authors

Poveshchenko AF,Markova EV,Korotkova NA,Yakushenko EV,Abramov VV,Kozlov VA

doi

10.1023/a:1015112729103

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

65-7

issue

1

eissn

0007-4888

issn

1573-8221

journal_volume

133

pub_type

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