Effects of fullerene C60 nanocomposites on human platelet aggregation.

abstract：:Comparative study on inbred mouse stains showed that in vitro response of T lymphocytes from tuberculosis-susceptible I/St mice to mycobacterial antigens did not differ from that of T lymphocytes from resistant mouse strains. The defect appeared only in the presence of virulent mycobacteria and was not related to T ly...

journal_title：Bulletin of experimental biology and medicine

authors： Radaeva TV,Nikonenko BV

更新日期：2000-06-01 00:00:00

abstract：:Toxicity of different types of manganese nanoparticles against glioblastoma U-87MG and U-251 cells and normal human cells was studied using MTT test. The selectivity of the toxic effect of nanoparticles was evaluated as the ratio of 50% cytotoxic concentration (СС50) for human embryos fibroblasts (FECh-15) to their СС...

journal_title：Bulletin of experimental biology and medicine

authors： Razumov IA,Zav'yalov EL,Troitskii SY,Romashchenko AV,Petrovskii DV,Kuper KE,Moshkin MP

更新日期：2017-08-01 00:00:00

abstract：:We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4(+) T cells and an increase in the count of central CD8(+) memory T cells in these patients....

journal_title：Bulletin of experimental biology and medicine

authors： Korolevskaya LB,Shmagel KV,Saidakova EV,Shmagel NG,Slobodchikova SV,Chereshnev VA

更新日期：2016-06-01 00:00:00

abstract：:We studied the course and outcome of pregnancy in the model of inflammation of internal genital organs in female rats. It was shown that inflammation of internal genital organs impairing the state of the lymphatic region of the uterus and adnexa and relationship between the drainage and detoxification function therein...

journal_title：Bulletin of experimental biology and medicine

authors： Dergacheva TI,Borodin YI,Konenkov VI

更新日期：2014-10-01 00:00:00

abstract：:Experiments on rat model of toxic liver damage (CCl4, subcutaneously) have demonstrated that selenium nanopreparation on arabinogalactan matrix and partially arabinogalactan alone prevented the development of oxidative stress assessed by the balance of LPO and antioxidant defense processes. ...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LI,Karpova EA,Vlasov BY,Sukhov BG,Mov BA

更新日期：2015-06-01 00:00:00

abstract：:Comparative analysis of proteoglycans in the control and tumor tissue of human mammary gland revealed disorders in the biosynthesis of dermatan sulfate proteoglycans in tumor cells. Using the methods of reverse transcription-PCR and Western blotting for the analysis of decorin expression we showed that these disorders...

journal_title：Bulletin of experimental biology and medicine

authors： Rykova VI,Grigorieva EV,Chernenko AV,Eshenko TY,Dymshits GM

更新日期：2007-09-01 00:00:00

abstract：:New methods of restriction fragment length polymorphism analysis were developed to distinguish polymorphic variants C190T, G191A, G857A, and 859Del of the NAT2 gene located close to each other. ...

journal_title：Bulletin of experimental biology and medicine

authors： Nikishina MV,Vavilin VA,Lyakhovich VV

更新日期：2008-10-01 00:00:00

abstract：:Treatment with a combination of artrofoon and anaferon significantly reduced clinical and laboratory parameters of rheumatoid inflammation and significantly decreased the content of antiinflammatory cytokines in the blood. These findings attest to antiinflammatory and immunomodulating effects of these preparations. ...

journal_title：Bulletin of experimental biology and medicine

authors： Petrov VI,Babaeva AR,Solodenkova KS,Cherevkova EV,Zabolotneva YA,Kachanova MV,Sergeeva SA

更新日期：2009-09-01 00:00:00

abstract：:Effect of one-day and chronic (3 week) drinking of 0.1% caffeine as a single source of fluid on anxiety in rats with different anxiety level (either genetically determined or individually acquired) was studied. When housed in groups, Fisher-344 rats had a significantly higher anxiety level than WAG/G rats. When the ra...

journal_title：Bulletin of experimental biology and medicine

authors： Sudakov SK,Medvedeva OF,Rusakova IV,Figurina IB

更新日期：2001-12-01 00:00:00

abstract：:Serum activity of tartrate-resistant acid phosphatase 5b (TRAP 5b) in patients with breast cancer and prostate cancer having bone metastases was much higher than in healthy donors and patients without skeletal injuries. TRAP 5b activity in patients with breast cancer and multiple bone metastases surpassed that in pati...

journal_title：Bulletin of experimental biology and medicine

authors： Lyubimova NV,Pashkov MV,Tyulyandin SA,Gol'dberg VE,Kushlinskii NE

更新日期：2004-07-01 00:00:00

abstract：:Lipemia modeled by injections of Triton WR-1339 (500 mg/kg) and poloxamer 407 (500 mg/kg) to mice were compared. LP fraction and subfraction compositions were compared by small-angle X-ray scattering on a diffractometer. Both compounds in the same dose caused a sharp increase in serum concentrations of total cholester...

journal_title：Bulletin of experimental biology and medicine

authors： Loginova VM,Tuzikov FV,Tuzikova NA,Korolenko TA

更新日期：2013-06-01 00:00:00

abstract：:Comparative study of cultured human bone marrow and adipose tissue (lipoaspirate) mesenchymal stem cells was carried out. The main morphological parameters, proliferative activity, expression of surface and intracellular markers of these cells were characterized. Flow cytofluorometry and histological staining showed t...

journal_title：Bulletin of experimental biology and medicine

authors： Romanov YA,Darevskaya AN,Merzlikina NV,Buravkova LB

更新日期：2005-07-01 00:00:00

abstract：:Expression of glucocorticoid receptor protein in the hippocampus and frontal cortex of male and female rats during the 1st, 2nd, and 3rd weeks of life was studied by Western blot hybridization. In the frontal cortex, the concentration of receptor protein progressively increased from the 1st to the 3rd week of life; in...

journal_title：Bulletin of experimental biology and medicine

authors： Ordyan NE,Galeeva AY,Pivina SG

更新日期：2008-08-01 00:00:00

abstract：:We studied the effect of audiovisual stimulation training course on physical development, functional state of the cardiovascular system, blood biochemical parameters, and hormonal status of athletes. The training course led to improvement of physical performance and adaptive capacities of the circulatory system, incre...

journal_title：Bulletin of experimental biology and medicine

authors： Golovin MS,Golovin MS,Aizman RI

更新日期：2016-09-01 00:00:00

abstract：:We measured activity of angiotensin-converting enzyme in plasma and tissue of NISAG and normotensive WAG rats. In different organs of NISAG rats, activity of this enzyme did not differ from the corresponding values of WAG rats, although enzyme activity in the plasma of NISAG rats was significantly lower than that of W...

journal_title：Bulletin of experimental biology and medicine

authors： Cherkasova OP,Fedorov VI,Markel AL

更新日期：2005-10-01 00:00:00

abstract：:Experiments on rats showed that blockade of norepinephrine reuptake in the early reperfusion period after focal myocardial ischemia aggravates myocardial injury and abolishes the protective effect of ischemic preconditioning. ...

journal_title：Bulletin of experimental biology and medicine

authors： Naumenko SE,Latysheva TV,Gilinskii MA

更新日期：2010-12-01 00:00:00

abstract：:Administration of granulocyte CSF preparation to patients with chronic heart failure produced a hemostimulating effect and increased the content of leukocytes and neutrophils in the peripheral blood. Granulocyte CSF induced mobilization of bone marrow progenitor cells into the peripheral blood. The content of hemopoie...

journal_title：Bulletin of experimental biology and medicine

authors： Konenkov VI,Pokushalov EA,Poveshchenko OV,Kim II,Romanov AB,Guleva NA,Bernvald VV,Soloviova AO,Yankayte EV,Poveshchenko AF,Karaskov AM

更新日期：2012-05-01 00:00:00

abstract：:Transplantation of erythroid and bone marrow cells to irradiated mice stimulated exogenous colony formation. Pretreatment of erythroid cells with specific rabbit antiserum to erythroblasts abolished this effect. The reverse transcriptase polymerase chain reaction revealed the presence of mRNA for interleukin-1alpha, i...

journal_title：Bulletin of experimental biology and medicine

authors： Sennikov SV,Inzhelevskaya TV,Eremina LV,Kozlov VA

更新日期：2000-12-01 00:00:00

abstract：:Free radical oxidation of arachidonic acid with soybean lipoxygenase was accompanied by inhibition of retinal synthesis from beta-carotene catalyzed by enzyme preparation from rabbit intestinal mucosa. Lipoxygenase inhibitor salicylhydroxamic acid and antioxidants suppressing free radical reactions (ethyl gallate, alp...

journal_title：Bulletin of experimental biology and medicine

authors： Gessler NN,Gomboeva SB,Shumaev KB,Bykhovskii VY,Lankin VZ

更新日期：2001-05-01 00:00:00

abstract：:Application of anxiolytic drug Selank to hippocampal slices increased the amplitude and discharge rate of spontaneous inhibitory postsynaptic currents in rat hippocampal pyramidal CA1 neurons. In some neurons, Selank-induced up-regulation of spontaneous inhibitory postsynaptic currents was preceded by a transient decr...

journal_title：Bulletin of experimental biology and medicine

authors： Povarov IS,Kondratenko RV,Derevyagin VI,Myasoedov NF,Skrebitsky VG

更新日期：2017-03-01 00:00:00

abstract：:We studied cardiac pumping function in the offspring of rats subjected to swimming exercise and the offspring of untrained rats. The rat pups were adapted for swimming with stepwise increasing load from day 21 to 70 life. At the age of 21 and 70 days, offspring of trained rats showed lower HR and significantly higher ...

journal_title：Bulletin of experimental biology and medicine

authors： Valeev AM,Abzalov NI,Abzalov RA,Nigmatullina RR,Abzalov RR,Nikitin AS

更新日期：2012-07-01 00:00:00

abstract：:Penetration of pegylated (enveloped in polyethylene glycol) gold nanoparticles 5 and 30 nm in diameter through the placental barrier was studied in pregnant rats injected intravenously with these particles in a dose of about 0.8 mg Au/kg on day 10 of gestation. The particles were visualized in tissues by silver nitrat...

journal_title：Bulletin of experimental biology and medicine

authors： Tsyganova NA,Khairullin RM,Terentyuk GS,Khlebtsov BN,Bogatyrev VA,Dykman LA,Erykov SN,Khlebtsov NG

更新日期：2014-07-01 00:00:00

abstract：:Proinflammatory markers were evaluated in patients with chronic heart failure of ischemic origin and essential hypertension with preserved left-ventricular ejection fraction before and after a 6-month course of simvastatin therapy (20 mg/day). The study was carried out in 125 patients with diastolic dysfunction manife...

journal_title：Bulletin of experimental biology and medicine

authors： Pinchuk TV,Fedulaev YN,Khairetdinova GA,Denisova NN,Chura OV,Logunova IY

更新日期：2014-09-01 00:00:00

abstract：:The study examined maturation of preovulatory germinal vesicles oocytes (GV oocytes) induced by gonadotropic hormone PMSG in the inbred C57Bl/6J mice (viewed as a gold standard for diverse biomedical studies) as well as in the first generation hybrid C57Bl/6J×СВА/lac and СВА/lac×C57Bl/6J mice at various ages. The most...

journal_title：Bulletin of experimental biology and medicine

authors： Riabukha YA,Petrova DA,Zatsepina OV

更新日期：2019-09-01 00:00:00

abstract：:Single intramuscular injection of selective of NMDA receptor blocker memantine in the maximum dose of 20 mg/kg prevented the development of acute generalized tonic-clonic kainate seizures in 60% rats, but did not alleviate clonic kainate seizures and prevented chronic kainate lethality in only 30% rats. Intramuscular ...

journal_title：Bulletin of experimental biology and medicine

authors： Serdyuk SE,Gmiro VE,Veselkina OS

更新日期：2014-05-01 00:00:00

abstract：:A series of short neurotoxins (molecular weight 3500-5000 D) was isolated from Vietnamese scorpion B. occitanus sp. All these toxins blocked generation of action potentials (this effect depended on their molecular weight), but did not change conduction velocity and excitation threshold of the nerve. ...

journal_title：Bulletin of experimental biology and medicine

authors： Hoang NA,Maksimov GV,Berezin BB,Piskarev VE,Yamskov IA

更新日期：2001-10-01 00:00:00

abstract：:The content of MMP-8 and MMP-9 in oral fluid of 145 patients (95 women and 50 men, 18-52 years) was measured by enzyme immunoassay. We examined 63 subjects with the intact periodontium and 82 patients with chronic generalized periodontitis (25 patients with mild disease, 45 patients with moderate disease, and 12 patie...

journal_title：Bulletin of experimental biology and medicine

authors： Kushlinskii NE,Solovykh EA,Karaoglanova TB,Bayar U,Gershtein ES,Troshin AA,Kostyleva OI,Grinin VM,Maksimovskaya LN,Yanushevitch OO

更新日期：2011-12-01 00:00:00

abstract：:Quantitative assay of nitric oxide (NO) and iron (Fe) was carried out by the electron paramagnetic resonance (EPR) method in epidermal derivative (hair) of 45 liquidators of the Chernobyl accident, 30 employees of radiological institutions having contact with radiation, and 50 students of Vladimir State University, mo...

journal_title：Bulletin of experimental biology and medicine

authors： Petukhov VI,Baumane LK,Reste ED,Zvagule TY,Romanova MA,Shushkevich NI,Sushkova LT,Skavronsky SV,Shchukov AN

更新日期：2013-04-01 00:00:00

abstract：:Alofanib is a potential allosteric inhibitor of FGFR2 used in oncology. The inhibitor blocks the extracellular part of the receptor and prevents its binding with the ligand. Alofanib suppressed proliferation of endothelial cells, their migration activity, and ability to form vessellike structures in vitro and signific...

journal_title：Bulletin of experimental biology and medicine

authors： Khochenkov DA,Solomko ES,Peretolchina NM,Ryabaya OO,Stepanova EV

更新日期：2015-11-01 00:00:00

abstract：:Local injection of 4 nmol moxonidine (unilaterally) into the rostroventrolateral medulla of spontaneously hypertensive rats (SHR-SP) decreased mean blood pressure and heart rate by 24+/-3 and 3+/-4%, respectively. Pretreatment with the I1/alpha2-receptor antagonist efaroxan abolished the moxonidine-induced decrease in...

journal_title：Bulletin of experimental biology and medicine

authors： Khokhlova ON,Murashev AN,Medvedev OS

更新日期：2001-04-01 00:00:00