Relationship between H+ transfer through human erythrocyte membrane and temperature.

abstract：:New methods of restriction fragment length polymorphism analysis were developed to distinguish polymorphic variants C190T, G191A, G857A, and 859Del of the NAT2 gene located close to each other. ...

journal_title：Bulletin of experimental biology and medicine

authors： Nikishina MV,Vavilin VA,Lyakhovich VV

更新日期：2008-10-01 00:00:00

abstract：:Structural characteristics of the adrenal medulla in hypertensive NISAG rats (hereditary stress-induced arterial hypertension) were studied during various periods of postnatal ontogeny. Signs of hyperplasia of the adrenal medulla were most pronounced in adult hypertensive animals with persistent arterial hypertension,...

journal_title：Bulletin of experimental biology and medicine

authors： Buzueva II,Filyushina EE,Shmerling MD,Markel AL,Yakobson GS

更新日期：2006-12-01 00:00:00

abstract：:We studied the seasonal effects of peptide preparation Selank on orientation and exploratory activity in 36 arctic ground squirrels Citellus undulatus in the open-field and hole-board tests. Selank most significantly increased behavioral activity of hibernating animals in the spring and fall. The test peptide had no e...

journal_title：Bulletin of experimental biology and medicine

authors： Semenova TP,Kozlovskaya MM,Zuikov AV,Kozlovskii II,Andreeva LA

更新日期：2005-12-01 00:00:00

abstract：:The absence of negative effects of anoceptin on the liver tissue and detoxifying function was proven experimentally in vitro and in vivo. It was proven for the first time that comenic acid (anoceptin active substance) in concentrations of 10(-4)-10(-12) does not modulate the growth of liver explants from 10-12-day chi...

journal_title：Bulletin of experimental biology and medicine

authors： Kipenko AV,Penniyaynen VA,Lopatina EV,Tsyrlin VA,Lobov GI,Krylov BV

更新日期：2010-12-01 00:00:00

abstract：:Analysis of contribution of sympathetic and parasympathetic systems into heart rate variability carried out using atenolol and atropine showed that August rats are characterized by enhanced tone of the sympathetic system and reduced tone of the parasympathetic system compared to Wistar rats. Reduced tone of the parasy...

journal_title：Bulletin of experimental biology and medicine

authors： Kirillina TN,Usacheva MA,Belkina LM

更新日期：2006-10-01 00:00:00

abstract：:We performed morphofunctional analysis of cultured rabbit buccal epithelial cells in the primary culture, during passaging, and upon interaction with collagen substrates. Three different morphological types were identified. It was demonstrated that precursors of rabbit buccal epithelium were characterized by high prol...

journal_title：Bulletin of experimental biology and medicine

authors： Chentsova EV,Konyushko OI,Makarov MS,Egorova NS,Zinov'ev MY,Borovkova NV

更新日期：2015-05-01 00:00:00

abstract：:A course of ascovertin therapy reduced manifestations of perifocal inflammation and atresia of growing follicles, corrected vascular disorders and changes in the tissue volume ratios outside the necrotic zone after monopolar coagulation of the ovaries in rats. The drug prevented the increase in blood viscosity, erythr...

journal_title：Bulletin of experimental biology and medicine

authors： Logvinov SV,Plotnikov MB,Tikhonovskaya OA,Bukharina IY,Maslov MY,Petrova MS

更新日期：2003-04-01 00:00:00

abstract：:We studied electrophysiological parameters and morphological changes in the adrenal glands and spleen of CBA mice feeding a low-choline diet and/or ethanol-containing diet. The polarization coefficient underwent similar changes in the adrenal glands and spleen, which was associated with different contribution of imped...

journal_title：Bulletin of experimental biology and medicine

authors： Tornuev YV,Nepomnyashchikh LM,Koldysheva EV

更新日期：2005-11-01 00:00:00

abstract：:The rats were divided into groups demonstrating extremely high and low stress reactivity depending on the results of testing for the nociceptive threshold and thermolability in response to bacterial lipopolysaccharide administration. Specific structural features of the nucleus and mitochondria were revealed in neurons...

journal_title：Bulletin of experimental biology and medicine

authors： Potanin MB,Tumanov VP,Pisarev VB

更新日期：2007-11-01 00:00:00

abstract：:Plasma cytokine concentration in patients with Parkinson's disease and mutation in GBA gene, in patients with sporadic Parkinson's disease, and in healthy volunteers were measured by ELISA and multiplex analysis. In patients with Parkinson's disease and mutation in GBA gene, elevated plasma concentrations of IL-1β and...

journal_title：Bulletin of experimental biology and medicine

authors： Miliukhina IV,Usenko TS,Senkevich KA,Nikolaev MA,Timofeeva AA,Agapova EA,Semenov AV,Lubimova NE,Totolyan AA,Pchelina SN

更新日期：2020-02-01 00:00:00

abstract：:Our findings indicate that expression of matrix metalloproteinase-2 is an important prognostic marker of invasive potential of pancreatic tumors. Expression of this marker in neuroendocrine tumors (particularly in gastrinomas) can be used as a differential diagnostic criterion characterizing more malignant phenotype o...

journal_title：Bulletin of experimental biology and medicine

authors： Gurevich LE

更新日期：2003-11-01 00:00:00

abstract：:The age-related features of ultrastructural reorganization of cardiomyocytes were studied in rats with anthracycline-induced injury. The development of regenerative and plastic insufficiency of cardiomyocytes in animals of various age groups was accompanied by stereotypic ultrastructural reorganization. The major chan...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh LM,Lushnikova EL,Molodykh NA,Klinnikova MG,Molodykh OP

更新日期：2011-05-01 00:00:00

abstract：:We studied a biomaterial for a new domestic product, a biological envelope for implantation of cardiac electronic devices. The product is designed to prevent complications after pacemaker implantation and to facilitate the reimplantation procedure. By chemical and biological processing of raw materials (submucosa of p...

journal_title：Bulletin of experimental biology and medicine

authors： Shadrina DV,Venediktov AA,Evdokimov SV,Vaskovskii VA,Artyukhina EA,Revishvili AS,Durmanov SS,Bazylev VV

更新日期：2020-01-01 00:00:00

abstract：:The local anaphylactic reaction and the effects of histamine during blocking of the slow sodium-calcium channels by isoptine were investigated in the spontaneously contracting oracle of the atrium of a guinea pig previously sensitized to egg albumin. Simultaneously with the intracellular recording of the potentials, i...

journal_title：Bulletin of experimental biology and medicine

authors： Khodorov BI,Voronovitskii EG,Ignat'eva VB

更新日期：1975-01-01 00:00:00

abstract：:Immunohistochemical and morphometric analysis of the microcirculatory bed in the tumor and non-tumor parenchyma of the prostate was carried out with the use of endothelial cell marker CD34 in patients treated by high-intensity focused ultrasound (HIFU). The numerical density of microvessels in the adenocarcinoma focus...

journal_title：Bulletin of experimental biology and medicine

authors： Bakarev MA,Levin VP,Kachesov IV,Abdullaev NA,Neimark AI

更新日期：2018-09-01 00:00:00

abstract：:Electron microscopy of the pineal gland in gamma-irradiated rats treated with epithalon revealed ultrastructural signs attesting to enhancement of its functional activity. ...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VK,Yakovleva ND,Popuchiev VV,Kvetnoi IM,Manokhina RP

更新日期：2001-01-01 00:00:00

abstract：:Morphological study of allotransplants of rat embryonic neocortex 14-18 months after transplantation into the neocortex, lateral cerebral ventricle, and sciatic nerve of adult animals revealed death of nerve and glial cells in the delayed postoperation period independently on the site of transplantation. After heterot...

journal_title：Bulletin of experimental biology and medicine

authors： Petrova ES,Otellin VA

更新日期：2003-09-01 00:00:00

abstract：:The linear parameters and number of Langerhans islets were evaluated in rats with alloxaninduced diabetes mellitus after transplantation of fetal pancreatic tissue to the anterior chamber of the eye. The islets significantly increased in size by week 3 after surgery and a trend to an increase in their number was obser...

journal_title：Bulletin of experimental biology and medicine

authors： Kulikov DA,Kulikov AV,Arkhipova LV,Smirnova GN,Dreval' AV,Tikhonova LP,Gaivoronskii IV,Sukhikh GT

更新日期：2015-01-01 00:00:00

abstract：:The development of experimental type II diabetes mellitus in rats was accompanied by dysfunction of inhibitory and stimulatory heterotrimeric G-proteins, components of hormone-sensitive adenylate cyclase signal system. The function of inhibitory G-proteins decreased most significantly under these conditions, which is ...

journal_title：Bulletin of experimental biology and medicine

authors： Shpakov AO,Kuznetsova LA,Plesneva SA,Bondareva VM,Guryanov IA,Vlasov GP,Pertseva MN

更新日期：2006-12-01 00:00:00

abstract：:The development of MPTP-induced depressive syndrome in rats was accompanied by activation of prolyl endopeptidase and dipeptidyl peptidase IV in the brain frontal cortex. Prolyl endopeptidase activity in the striatum also increased under these conditions. Our results indicate that proline-specific peptidases in the ta...

journal_title：Bulletin of experimental biology and medicine

authors： Krupina NA,Zolotov NN,Bogdanova NG,Orlova IN,Khlebnikova NN,Kryzhanovskii GN

更新日期：2006-11-01 00:00:00

abstract：:Afala (ultralow-dose antibodies to prostate-specific antigen) injected for 60 days to rats with hormone-induced prostatitis caused by sulpiride prevented the development of prostatic hyperplasia and reduced the severity of histological changes. The effect of Afala was superior to that of the reference drug (Serenoa re...

journal_title：Bulletin of experimental biology and medicine

authors： Savelieva KV,Borovskaya TG,Kheyfets IA,Dugina JL,Sergeeva SA,Epstein OI

更新日期：2007-11-01 00:00:00

abstract：:Isolation and identification of rat brain protein regulated by serotonin-modulated protein SMP-69 is described. Intracerebral administration of anti-SMP-69 antibodies activates cerebral cortex cell genome and increases the content of electropheretic fraction 28. Intracerebral administration of isolated and purified pr...

journal_title：Bulletin of experimental biology and medicine

authors： Mekhtiev AA

更新日期：2000-08-01 00:00:00

abstract：:Autooxidation of low-density lipoproteins during incubation at 37 degrees C was accompanied by accumulation of LPO products, decrease in UV autofluorescence (FUV), and increase in autofluorescence in the visible band (FVIS). The degree of low-density lipoprotein modification was estimated by calculating the FVIS/FUV r...

journal_title：Bulletin of experimental biology and medicine

authors： Aidyraliev RK,Azizova OA,Vakhrusheva TV,Lopukhin YM,Mirrakhimov MM

更新日期：2006-10-01 00:00:00

abstract：:We estimated the percentage of CD4+ lymphocytes synthesizing IFN-gamma and IL-4 in the peripheral blood and measured the concentrations of IL-1, IL-6, and TNF-alpha in lochia of patients with postpartum endometritis. T lymphocytes with intracellular IFN-gamma prevailed in women with physiological course of the postpar...

journal_title：Bulletin of experimental biology and medicine

authors： Sukhikh GT,Kasabulatov NM,Van'ko LV,Ordzhonikidze NV,Veryasov VN,Danelyan SZh

更新日期：2005-12-01 00:00:00

abstract：:The location and activities of nitric oxide synthases in synovial cells during different stages of inflammatory process were studied by the immunocytochemical method in animals with experimental rheumatoid arthritis. Direct involvement of the NOergic mechanisms in the development of adjuvant arthritis was demonstarted...

journal_title：Bulletin of experimental biology and medicine

authors： Belogolovykh LA,Dubikov AI,Medved' EE

更新日期：2007-05-01 00:00:00

abstract：:Differences in the gene expression profiles in resident macrophages (in particular, Kupffer cells) and monocytes were revealed. However, these differences in gene expression profiles do not allow considering resident liver macrophages as purely M2 macrophages and monocytes as purely M1 macrophages. At the same time, a...

journal_title：Bulletin of experimental biology and medicine

authors： Nikitina MP,Elchaninov AV,Lokhonina AV,Makarov AV,Tagirova MK,Grinberg MV,Bolshakova GB,Glinkina VV,Goldshtein DV,Fatkhudinov TK

更新日期：2020-02-01 00:00:00

abstract：:We analyzed association of potentially regulatory polymorphisms (rs590352, rs11542583, rs3829202, rs207258, and rs4796672) with breast cancer. A significant association was found between this disease and rs2072580T>A (p=0.001) located in the overlapping promoter regions of the SART3 and ISCU genes. In women with AA an...

journal_title：Bulletin of experimental biology and medicine

authors： Degtyareva AO,Leberfarb EY,Efimova EG,Brusentsov II,Usova AV,Lushnikova EL,Merkulova TI

更新日期：2020-05-01 00:00:00

abstract：:We studied etiologic structure of bacterial intestinal infections in monkeys of Adler nursery. A total of 533 monkeys with diarrhea syndrome and monkeys dead from intestinal infections, as well as clinically healthy monkeys and animals dead from other pathologies were examined by bacteriological and molecular-genetic ...

journal_title：Bulletin of experimental biology and medicine

authors： Ardasheliya SN,Kalashnikova VA,Dzhikidze EK

更新日期：2011-10-01 00:00:00

abstract：:Metabolic processes in the brain cortex of albino rats with prenatal and postnatal alcohol intoxication were studied by the method of electron paramagnetic resonance. Accumulation of superoxide radical-generating agents, inactivation of superoxide dismutase, and increase in nitric oxide concentration were detected. Ac...

journal_title：Bulletin of experimental biology and medicine

authors： Museridze DP,Sanikidze TV,Svanidze IK

更新日期：2006-09-01 00:00:00

abstract：:The incidence and prevalence of Actinobacillus actinomycetemcomitans, Porphyronmonas gingivalis, and Tannerella forsythensis in specimens of subgingival dental deposit were evaluated in 495 residents of St. Petersburg aged 6-82 years. The microorganisms were detected by gene-specific PCR of 16S rDNA. In accordance wit...

journal_title：Bulletin of experimental biology and medicine

authors： Chukhlovin AB,Solovyova AM,Matelo SK,Kobiyasova IV,Morosova EB,Hokhlacheva AV,Teplyakov BG,Syssoev KA,Konstantinova VE,Matelo LN,Totolian AA

更新日期：2007-10-01 00:00:00