Quantitative assessment of neurons and neuroglia with computer morphometry.

abstract：:We studied proliferation, migration, and secretion of NO by bone marrow multipotent mesenchymal stromal cells from Wistar rats during conditioning under hypoxic and hyperglycemic conditions and the effect of erythropoietin on these parameters. A stimulating effect of erythropoietin on cell proliferation under normal c...

journal_title：Bulletin of experimental biology and medicine

authors： Lykov AP,Nikonorova YV,Bondarenko NA,Poveshchenko OV,Kim II,Poveshchenko AF,Konenkov VI

更新日期：2015-08-01 00:00:00

abstract：:We studied the effect of ozonized physiological saline on phagocytic properties of polymorphonuclear neutrophilic leukocytes from dog blood. Intravenous infusion of the examined doses of ozonized saline stimulated phagocytosis. Repeated intravenous infusion (48 h after) of the same dose was followed by a significant d...

journal_title：Bulletin of experimental biology and medicine

authors： Volkhovskaya NB,Tkachenko SB,Belopolsky AA

更新日期：2008-11-01 00:00:00

abstract：:Location of cathepsin D and elastase in rat uterus was studied by electron-histochemical method. Activities of both proteinases in the myometrium was detected in lysosomes of smooth-muscle cells, macrophages, and fibroblasts. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ryvnyak VV,Gudumak VS,Dulgieru OF

更新日期：2003-08-01 00:00:00

abstract：:We studied morphological changes in rat abdominal aorta and vena cava inferior induced by endovascular microwave destruction. This treatment induced thrombosis and necrosis of the vascular walls, but fibrous framework was not completely destroyed. Then we observed irreversible changes in vessels: obliteration, atrophy...

journal_title：Bulletin of experimental biology and medicine

authors： Denisov-Nikol'skii YI,Shafranov VV,Borkhunova EN,Doktorov AA,Mikhaleva LM,Mikhalev AP

更新日期：2002-07-01 00:00:00

abstract：:Measurements with extracellular microelectrode technique showed that depolarization of motor nerve terminals in frog cutaneous pectoris muscle with high-potassium solution (40 mM K(+)) increased frequency of miniature end-plate currents. Both fast intracellular calcium chelator BAPTA-AM and slow chelator EGTA-AM equal...

journal_title：Bulletin of experimental biology and medicine

authors： Zefirov AL,Grigor'ev PN

更新日期：2008-12-01 00:00:00

abstract：:A simple method for the diagnosis of insulin resistance, easily realized in clinical practice, is developed in order to detect patients at a high risk of diseases associated with this condition. The metabolic index is estimated as the proportion of triglycerides and glucose values to quadratic HDL cholesterol value (i...

journal_title：Bulletin of experimental biology and medicine

authors： Roitberg GE,Dorosh ZhV,Sharkhun OO

更新日期：2015-01-01 00:00:00

abstract：:Comparative analysis of the parameters of LPO, antioxidant defense (AOD), and the thiol/disulfide system was performed in fertile and infertile males of reproductive age carrying different genotypes of the glutathione system genes. Blood plasma, blood hemolysate, and ejaculate served as specimens for biochemical studi...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LI,Kurashova NA,Bairova TA,Dolgikh MI,Ershova OA,Natyaganova LV,Dashiev BG,Gutnik IN,Koroleva NV

更新日期：2017-07-01 00:00:00

abstract：:The incidence of 5 polymorphisms of N-acetyltransferase-2 gene was evaluated in patients with lung cancer. A803G polymorphism is a factor of lung cancer resistance in tobacco smoking Caucasians in Novosibirsk. Opposite effects of NAT2 gene polymorphisms on the risk of lung cancer are possible. ...

journal_title：Bulletin of experimental biology and medicine

authors： Nikishina MV,Vavilin VA,Makarova SI,Lyakhovich VV

更新日期：2007-01-01 00:00:00

abstract：:The cell composition of leukocyte infiltrates in the endometrium, myometrium, and vaginal walls was studied in Wistar rats with modeled chronic endomyometritis after administration of IFNγ (0.1 μg/100 g body weight) in different daily regimens (10.00 or 20.00). Morning injections of this cytokine ameliorated inflammat...

journal_title：Bulletin of experimental biology and medicine

authors： Dergacheva TI,Shurlygina AV,Abdalova AM,Klimontov VV,Trufakin VA,Letyagin AY

更新日期：2020-08-01 00:00:00

abstract：:The anti-ischemic effect of synthetic and pharmacologically tested anxiolytic afobazole (10 mg/kg intravenously) was studied on anesthetized rats with acute endocardial ischemia caused by isoproterenol infusion (20 mg/kg/min). A calcium antagonist verapamil (1 mg/kg intravenously) belonging to the group of phenyl alky...

journal_title：Bulletin of experimental biology and medicine

authors： Seredenin SB,Tsorin IB,Vititnova MB,Stolyaruk VN,Chichkanov GG,Kryzhanovskii SA

更新日期：2013-10-01 00:00:00

abstract：:T cells were most sensitive to cyclophosphamide in DBA/2 mice, while in C57Bl/6 mice both T and B cells were sensitive. The formation of antibody-producing cells and the production of specific antibodies were delayed in DBA/2 mice immunized after pretreatment with antitumor drug. Accumulation of antibody-producing cel...

journal_title：Bulletin of experimental biology and medicine

authors： Masnaya NV,Churin AA,Borsuk OS,Sherstoboev EY

更新日期：2003-04-01 00:00:00

abstract：:We studied the effect of increased systemic levels of the proinflammatory cytokine IL-1β on the vasomotor reactions of pial microvessels in anesthetized rats under conditions of experimentally simulated progressively increasing acute normobaric hypoxia. Vital microscopy showed that more pronounced dilatation of pial v...

journal_title：Bulletin of experimental biology and medicine

authors： Mel'nikova NN,Baranova EV,Aleksandrova NP

更新日期：2020-11-01 00:00:00

abstract：:Antisense oligonucleotide to alpha2A-adrenoceptors increased the levels of mRNA (reverse polymerase chain reaction) and protein for a key executioner protease of apoptosis caspase-3 (immunoblotting assay) in the cerebral cortex of newborn rats. The relationship between the observed effect and low expression of alpha2-...

journal_title：Bulletin of experimental biology and medicine

authors： Men'shanov PN,Bannova AV,Il'inykh FA,Dygalo NN

更新日期：2007-03-01 00:00:00

abstract：:We studied the phospholipid composition of high-density lipoproteins in patients with hypercholesterolemia before and after treatment with simvastatin. Individual phospholipids were separated by thin-layer chromatography on glass plates coated with silica gel. It was found that apart from hypolipidemic effect, simvast...

journal_title：Bulletin of experimental biology and medicine

authors： Ozerova IN,Paramonova IV,Olfer'ev AM,Akhmedzhanov NM,Aleksandrova MA,Perova NV

更新日期：2001-08-01 00:00:00

abstract：:We studied the effect of Selank administered intraperitoneally in doses of 100, 300, and 1000 μg/kg to male Wistar rats 15 min prior to restraint stress on the content of aminotransferases and total protein concentration in blood serum and intensity of free radical oxidation in the liver. Under conditions of acute res...

journal_title：Bulletin of experimental biology and medicine

authors： Fomenko EV,Bobyntsev II,Kryukov AA,Ivanov AV,Andreeva LA,Myasoedov NF

更新日期：2017-08-01 00:00:00

abstract：:Experiments on rats showed that activation of the peripheral ion channel TRPM8 with menthol and rapid cooling (decrease in core temperature by 3°C) led to 1.5-fold activation of the expression of TRPV3 ion channel gene in the posterior hypothalamus, but had no effect on the expression of this gene in the anterior hypo...

journal_title：Bulletin of experimental biology and medicine

authors： Kozyreva TV,Evtushenko AA,Voronova IP,Khramova GM,Kozaruk VP

更新日期：2018-12-01 00:00:00

abstract：:The epileptogenic effects of applications of NMDA and kainic acid solutions to the frontal cortex were attenuated in rats receiving ketogenic diet (80% lipids, 3.3% carbohydrates, and 16.7% proteins) during 4 weeks. Spike latency increased, the power of focal epileptic activity decreased, and focus lifetime was shorte...

journal_title：Bulletin of experimental biology and medicine

authors： Kresyun VI,Polyasny VA,Godovan VV,Godlevsky LS

更新日期：2013-02-01 00:00:00

abstract：:Here we present the results of histochemical detection of 3β-hydroxysteroid dehydrogenase in neurons of the neocortex, cerebellum, and brainstem. The positive reaction was observed in a low number of neocortical, midbrain, and pontine neurons. The maximum number of positive neurons was detected in the cerebellar corte...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva VM

更新日期：2012-01-01 00:00:00

abstract：:We present a method of minimally invasive transcutaneous insertion of screws using a prefabricated extracorporeal navigation system using additive technologies (based on primary data obtained from the DICOM package in multi-detector computed tomography of the affected spine segment) according to the principle of perso...

journal_title：Bulletin of experimental biology and medicine

authors： Dotsenko IA,Kotomtsev VV,Medvinsky ID,Chertkov AK,Saveliev AV

更新日期：2020-04-01 00:00:00

abstract：:Taurine is an important endogenous agonist of glycine receptors (GlyR). Using the patchclamp technique, we measured chloride current induced by a short (600 msec) application of taurine (ITau) on isolated rat pyramidal neurons. pH of taurine solution in the applicator pipette was neutral (7.4) or acidic (7.0-5.0). App...

journal_title：Bulletin of experimental biology and medicine

authors： Solntseva EI,Bukanova YV,Kondratenko RV,Skrebitsky VG

更新日期：2019-06-01 00:00:00

abstract：:Lipemia modeled by injections of Triton WR-1339 (500 mg/kg) and poloxamer 407 (500 mg/kg) to mice were compared. LP fraction and subfraction compositions were compared by small-angle X-ray scattering on a diffractometer. Both compounds in the same dose caused a sharp increase in serum concentrations of total cholester...

journal_title：Bulletin of experimental biology and medicine

authors： Loginova VM,Tuzikov FV,Tuzikova NA,Korolenko TA

更新日期：2013-06-01 00:00:00

abstract：:Structure of arteries of different diameter in early and late periods of hypertension caused by experimental coarctation of the aorta was studied by histological and morphometric methods. Blood pressure was measured directly via catheterization of the common carotid artery and used for evaluation of hemodynamic in the...

journal_title：Bulletin of experimental biology and medicine

authors： Gansburgsky AN,Jaltsev AV

更新日期：2012-07-01 00:00:00

abstract：:Intranigral administration of glutamate to rats with parkinsonian syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine augmented the development of parkinsonian symptoms (oligokinesia and muscular rigidity), but did not affect motor activity of intact animals. Memantine administered intraperitoneally in pa...

journal_title：Bulletin of experimental biology and medicine

authors： Kucheryanu VG,Kryzhanovskii GN

更新日期：2000-07-01 00:00:00

abstract：:The dynamics of coenzyme Q10 concentration in the blood plasma, liver, and brain of passive and active rats was studied on the model of metabolic stress. This parameter was shown to differ in rats with various patterns of behavior. Dietary consumption of coenzyme Q10 in doses of 10 and 100 mg/kg body weight was follow...

journal_title：Bulletin of experimental biology and medicine

authors： Kirbaeva NV,Sharanova NE,Baturina VA,Zhminchenko VM,Pertsov SS,Vasil'ev AV

更新日期：2016-09-01 00:00:00

abstract：:Differential expression of type 1 cannabinoid receptors (CR1) was evaluated at different stages of human skin fibroblast transformation into terminally differentiated neurons. Immunocytochemical staining detected no CR1 on fibroblasts, but their transformation into induced pluripotent stem cells was accompanied by mar...

journal_title：Bulletin of experimental biology and medicine

authors： Bobrov MY,Bezuglov VV,Khaspekov LG,Illarioshkin SN,Novosadova EV,Grivennikov IA

更新日期：2017-06-01 00:00:00

abstract：:We carried out a retrospective immunohistochemical study of Ki-67, PCNA, Bcl-2, BAX, BclX, and VEGF expression in tumors of two groups of breast cancer patients with favorable and unfavorable course of the disease. Considerably enhanced VEGF expression was detected in tumors of patients with early relapses of breast c...

journal_title：Bulletin of experimental biology and medicine

authors： Kushlinskii NE,Orinovskii MB,Gurevich LE,Kazantseva IA,Talaeva ShZh,Shirokii VP,Ermilova VD,Dvorova EK,Ozherelev AS

更新日期：2004-02-01 00:00:00

abstract：:Preliminary injection of succinic semialdehyde into animals in experiments with hypoxia led to a lower concentration of free ammonia in their brain tissues than in control experiments in which the compound was not given. The enzyme system of the liver tissue catalyzes the oxidation of NAD-H-2 by succinic semialdeyde a...

journal_title：Bulletin of experimental biology and medicine

authors： Zubovskaya AM,Ostrovskaya RU,Tsybina NM

更新日期：1975-01-01 00:00:00

abstract：:Blood flow in reproductive organs was studied during experimental cessation of blood outflow in the testicular vein. This pathological state was accompanied by disturbances of the complex pathogenesis. The major component was autoregulatory focal ischemia, which resulted from the venoarterial response to venous hypert...

journal_title：Bulletin of experimental biology and medicine

authors： Artifeksov SB,Artyukhin AA

更新日期：2007-06-01 00:00:00

abstract：:We performed comparative analysis of hemodynamic in the periodontal microcirculatory bed in adolescents with arterial hypertension (AH) and morphological changes in the periodontal tissues of in hypertensive ISIAH rats of comparable biological age. In the periodontal tissues of adolescents with hypertension, the blood...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LR,Darenskaya MA,Kolesnikova LI,Grebenkina LA,Korytov LI,Batoroev YK,Belinskaya EI,Mikhalevich IM,Kolesnikov SI

更新日期：2020-10-01 00:00:00

abstract：:The rates of oxyhemoglobin drop and CO(2) release in dogs with magnetized and nonmagnetized blood were compared. Stationary magnetic field enhances blood oxygen capacity by no less than 24%. A hypothesis was proposed on formation of bioxyhemoglobin molecules under the effect of magnetic field, in which hem binds two O...

journal_title：Bulletin of experimental biology and medicine

authors： Zhernovoi AI,Skorik VI,Chirukhin VA,Sharshina LM

更新日期：2001-02-01 00:00:00