Abstract：
:Structure of arteries of different diameter in early and late periods of hypertension caused by experimental coarctation of the aorta was studied by histological and morphometric methods. Blood pressure was measured directly via catheterization of the common carotid artery and used for evaluation of hemodynamic in the cerebral basin. It was shown that the late period of hypertension is characterized by dilatation of medium arteries and constriction and increase tone of small arteries and arterioles. Comparison of blood pressure parameters with the parameters of inner diameter and thickness of the tunica media attests to progressive decrease of permissible tensile strength and initiation of rapture of the wall of small arteries and arterioles during chronic hypertension.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Gansburgsky AN,Jaltsev AVdoi
10.1007/s10517-012-1724-6subject
Has Abstractpub_date
2012-07-01 00:00:00pages
393-5issue
3eissn
0007-4888issn
1573-8221journal_volume
153pub_type
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