Oxidative status and citrate concentration in rat tissues during experimental hyperthyroidism and melatonin treatment.

abstract：:The effects of glucocorticoids on monocyte morphology and function in vitro and the results of high-dose budesonide therapy in patients with non-severe bronchial asthma were analyzed. Before therapy with inhalation glucocorticosteroid (budesonide) characteristics of blood monocytes and the effects of different concent...

journal_title：Bulletin of experimental biology and medicine

authors： Terpigorev SA,Il'chenko VA,Vasilenko IA,Slinchenko OI,Stotskaya TV,Markina TR,Paleev NR

更新日期：2003-06-01 00:00:00

abstract：:Differences in the gene expression profiles in resident macrophages (in particular, Kupffer cells) and monocytes were revealed. However, these differences in gene expression profiles do not allow considering resident liver macrophages as purely M2 macrophages and monocytes as purely M1 macrophages. At the same time, a...

journal_title：Bulletin of experimental biology and medicine

authors： Nikitina MP,Elchaninov AV,Lokhonina AV,Makarov AV,Tagirova MK,Grinberg MV,Bolshakova GB,Glinkina VV,Goldshtein DV,Fatkhudinov TK

更新日期：2020-02-01 00:00:00

abstract：:A combination of electrochemical lysis and photodynamic therapy were used to attain complete resorption of M-1 sarcoma in rats; both treatment modalities were used with minimum parameters. Fotolon served as the photosensitizer for photodynamic therapy. Accumulation of the sensitizer in the tumor and normal tissue was ...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhailovskaya AA,Kaplan MA,Brodskij RA,Bandurko LN

更新日期：2009-01-01 00:00:00

abstract：:During exacerbation of cytomegalovirus infection during pregnancy, cytomegalovirus proteins penetrate across the external membrane of placental villous syncytiotrophoblast and suppress activities of ATPase and Bcl-2 protein. Simultaneous increase in the content of annexin V and caspase 3 leads to structural disturbanc...

journal_title：Bulletin of experimental biology and medicine

authors： Lutsenko MT,Andrievskaya IA

更新日期：2016-01-01 00:00:00

abstract：:Isolation and identification of rat brain protein regulated by serotonin-modulated protein SMP-69 is described. Intracerebral administration of anti-SMP-69 antibodies activates cerebral cortex cell genome and increases the content of electropheretic fraction 28. Intracerebral administration of isolated and purified pr...

journal_title：Bulletin of experimental biology and medicine

authors： Mekhtiev AA

更新日期：2000-08-01 00:00:00

abstract：:Dihydroquercetin (flavonoid of plant origin) immobilized with an amino acid in lecithin nanoparticles promotes reduction of inflammatory reactions in the wound after thermal burn. The use of a liposomal complex in burn injury stabilizes endogenous antioxidant system and limits the secondary necrotic zone in the wounds...

journal_title：Bulletin of experimental biology and medicine

authors： Naumov AA,Shatalin YV,Potselueva MM

更新日期：2010-07-01 00:00:00

abstract：:Maximum magnetic resonance artifacts from stents are often determined by the presence of ferromagnetic compounds in the delivery system. We propose a mathematic model describing artifacts caused by nitinol stents. A method for evaluation of critical radial rigidity of the stents was developed. ...

journal_title：Bulletin of experimental biology and medicine

authors： Sergienko VI,Martynov AK,Petryaikin AV,Koshurnikov DS,Fadeev AA,Nikolaev DA,Karmazanovskii GG,Osipova NY,Fedorov VD

更新日期：2007-09-01 00:00:00

abstract：:Antioxidant properties of recombinant peroxiredoxin-6 and chimeric protein PSH combining peroxidase and superoxide dismutase activities were studied on the model of retrograde perfusion of isolated rat heart under conditions of H2O2-induced oxidative stress. The exogenous antioxidant proteins exhibited cardioprotectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Karaduleva EV,Mubarakshina EK,Sharapov MG,Volkova AE,Pimenov OY,Ravin VK,Kokoz YM,Novoselov VI

更新日期：2016-03-01 00:00:00

abstract：:We studied the incidence of chromosome aberrations in bone marrow cells and primary spermatocytes in various mouse strains. Experiments were performed on SAMP mice (accelerated aging), control SAMR mice, and long-living CBA and SHR mice. Experiments revealed a positive correlation between the age and the incidence of ...

journal_title：Bulletin of experimental biology and medicine

authors： Rozenfel'd SV,Togo EF,Mikheev VS,Popovich IG,Zabezhinskii MA,Anisimov VN

更新日期：2001-05-01 00:00:00

abstract：:We studied the mechanisms of erythropoiesis stimulation and effectiveness of Poetam, a preparation containing release-active anti-erythropoietin antibodies as a supplement treatment for experimental iron deficiency anemia during gestation. The results confirmed potency of combined therapy to stimulate erythropoiesis, ...

journal_title：Bulletin of experimental biology and medicine

authors： Burmina YV,Udut EV,Zhdanov VV,Sotnikova LS,Miroshnichenko LA,Simanina EV,Polyakova TY,Zyuz'kov GN,Chaikovskii AV,Stavrova LA,Epshtein OI,Dygai AM

更新日期：2016-04-01 00:00:00

abstract：:Taftsin, an endogenous peptide immunostimulator, exhibits also high antiulcer activity. In a dose of 0.6 micromol/kg Taftsin decreases the area of ulcerative lesions in albino rats on various models of ulceration. ...

journal_title：Bulletin of experimental biology and medicine

authors： Pavlov TS,Samonina GE

更新日期：2004-08-01 00:00:00

abstract：:Expression of glucocorticoid receptor protein in the hippocampus and frontal cortex of male and female rats during the 1st, 2nd, and 3rd weeks of life was studied by Western blot hybridization. In the frontal cortex, the concentration of receptor protein progressively increased from the 1st to the 3rd week of life; in...

journal_title：Bulletin of experimental biology and medicine

authors： Ordyan NE,Galeeva AY,Pivina SG

更新日期：2008-08-01 00:00:00

abstract：:We studied the effect of experimental liver injury of various origins (toxic, autoimmune, alcoholic, and mesenchymal) in the females on motility of spermatozoa in the offspring. The number of infertile (jerking and immotile) spermatozoa increased, whereas the number of fertile spermatozoa (progressive motile and slow ...

journal_title：Bulletin of experimental biology and medicine

authors： Bryukhin GV,Sizonenko ML

更新日期：2014-11-01 00:00:00

abstract：:The effects of neural progenitor and hemopoietic stem cells on C6 glioma cells were studied in in vivo and in vitro experiments. Considerable inhibition of proliferation during co-culturing of glioma cells with neural progenitor cells was revealed by quantitative MTT test and bromodeoxyuridine incorporation test. Labe...

journal_title：Bulletin of experimental biology and medicine

authors： Baklaushev VP,Grinenko NF,Savchenko EA,Bykovskaya SN,Yusubalieva GM,Viktorov IV,Bryukhovetskii AS,Bryukhovetskii IS,Chekhonin VP

更新日期：2012-02-01 00:00:00

abstract：:A stable preparation of agaricinic acid nanoparticles was obtained. The mean hydrodynamic size of nanoparticles according to photon correlation spectroscopy was 200 nm and zeta potential was -57 mV. Cytotoxic activity of agaricinic acid nanoparticles against human HepG2 hepatoma cells was evaluated. Nanoparticles with...

journal_title：Bulletin of experimental biology and medicine

authors： Gudkova OI,Demchenko AG,Shvets AV,Kuryakov VN,Sedyakina NE,Lyundup AV,Feldman NB,Gromovykh TI,Lutsenko SV

更新日期：2020-08-01 00:00:00

abstract：:The effects of a new thietanylbenzimidazole derivative (K-134) on estrous cycles, conception processes, and sexual behavior of female rats were studied. Two-week oral treatment with K-134 in doses of 5 and 50 mg/kg shortened the estrus phase and prolonged proestrus. Changes in sexual behavior were presented by activat...

journal_title：Bulletin of experimental biology and medicine

authors： Kuzubova EA,Bugaeva LI,Sergeeva SA,Petrov VI,Kataev VA,Kharlamov IV,Mal'tsev MV

更新日期：2015-09-01 00:00:00

abstract：:We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4(+) T cells and an increase in the count of central CD8(+) memory T cells in these patients....

journal_title：Bulletin of experimental biology and medicine

authors： Korolevskaya LB,Shmagel KV,Saidakova EV,Shmagel NG,Slobodchikova SV,Chereshnev VA

更新日期：2016-06-01 00:00:00

abstract：:Micro- and nanomolar concentrations of ganglioside GM1 improved viability of neuronal PC12 cells under conditions of oxidative stress and reduced H2O2-induced ROS accumulation in these cells. These effects were more pronounced at micromolar concentrations. GM1 in concentrations of 100 nM and 10 μM significantly and su...

journal_title：Bulletin of experimental biology and medicine

authors： Zakharova IO,Sokolova TV,Akhmetshina AO,Avrova NF

更新日期：2015-09-01 00:00:00

abstract：:Systemic administration of ACTH to rats with normal hormone production induced a rapid (started 3 min postinjection) and long-term (persisted 30 min) elevation of pain threshold. Complete inhibition of glucocorticoid production shortened the duration of ACTH-induced analgesia to 15 min. The biphasic effect of ACTH on ...

journal_title：Bulletin of experimental biology and medicine

authors： Bogdanov AI,Yarushkina NI

更新日期：2001-03-01 00:00:00

abstract：:Location of cathepsin D and elastase in rat uterus was studied by electron-histochemical method. Activities of both proteinases in the myometrium was detected in lysosomes of smooth-muscle cells, macrophages, and fibroblasts. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ryvnyak VV,Gudumak VS,Dulgieru OF

更新日期：2003-08-01 00:00:00

abstract：:The effect of melanin solutions on the skin exposed to UV irradiation (1,050 kJ/m(2)) depended on its dose and varied from photoprotection (0.005 mg/ml) to photosensitization and phototoxicity (burn, 0.1 mg/ml). These results suggest that doses of melanin preparations should be empirically selected to achieve optimum ...

journal_title：Bulletin of experimental biology and medicine

authors： Paramonov BA,Turkovskii II,Potokin IL,Chebotarev VY

更新日期：2002-04-01 00:00:00

abstract：:Phenotypical study was carried out in rats with pendulum movements. The animals exhibited a high level of abortive seizures in response to audiogenic stimuli and longer postictal catalepsy in comparison with those in Wistar population. Seizure severity positively correlated with the duration of poststimulus catalepsy ...

journal_title：Bulletin of experimental biology and medicine

authors： Alekhina TA,Kozhemyakina RV

更新日期：2019-12-01 00:00:00

abstract：:Typical signs of cardiomyoblasts were determined: high mitochondrial membrane potential and high number of mitochondria in these cells compared to fibroblasts. These signs can be used for identification of these cells. Energy-dependent accumulation of highly specific mitochondrial fluorescent probes applied for visual...

journal_title：Bulletin of experimental biology and medicine

authors： Khryapenkova TG,Plotnikov EY,Korotetskaya MV,Sukhikh GT,Zorov DB

更新日期：2008-10-01 00:00:00

abstract：:The intensity of calcium and phosphate accumulation in regenerating bone tissue decreased significantly during the posttraumatic period in 54 male CBA mice with acute hepatic intoxication. The formation of organic components of the bone decreased to a lesser degree. Creatine metabolism in the muscles of damaged segmen...

journal_title：Bulletin of experimental biology and medicine

authors： Stogov MV,Luniova SN,Tkachuk EA

更新日期：2010-10-01 00:00:00

abstract：:Experiments on rats showed that activation of the peripheral ion channel TRPM8 with menthol and rapid cooling (decrease in core temperature by 3°C) led to 1.5-fold activation of the expression of TRPV3 ion channel gene in the posterior hypothalamus, but had no effect on the expression of this gene in the anterior hypo...

journal_title：Bulletin of experimental biology and medicine

authors： Kozyreva TV,Evtushenko AA,Voronova IP,Khramova GM,Kozaruk VP

更新日期：2018-12-01 00:00:00

abstract：:Conditions of human BM and umbilical cord blood MSC in vitro differentiation in the hepatogenic direction were studied. Changes in cell morphology, phenotype, acquisition of the capacity to produce albumin and accumulate glycogen, express cytokeratin, alkaline phosphatase, and albumin mRNA indicated that BM and umbili...

journal_title：Bulletin of experimental biology and medicine

authors： Kosmacheva SM,Seviaryn IN,Goncharova NV,Petyovka NV,Potapnev MP

更新日期：2011-05-01 00:00:00

abstract：:We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum i...

journal_title：Bulletin of experimental biology and medicine

authors： Aksenov DV,Kaplun VV,Tertov VV,Sobenin IA,Orekhov AN

更新日期：2007-01-01 00:00:00

abstract：:The spatial and the amplitude-temporal parameters of cardiac body surface potentials were examined in female Wistar rats with experimental pulmonary hypertension during ventricular depolarization. The cardiac body surface potentials have been led from 64 subcutaneous electrodes evenly distributed across the chest surf...

journal_title：Bulletin of experimental biology and medicine

authors： Suslonova OV,Smirnova SL,Roshchevskaya IM

更新日期：2016-11-01 00:00:00

abstract：:The cardioprotective effects of Ganoderma lucidum extract were examined in experiments with global ischemia (45 min) and reperfusion (30 min) of isolated and perfused rat heart. The course of preventive administration of the extract in a dose of 400 mg/kg for 15 days diminished necrotic death of cardiomyocytes and red...

journal_title：Bulletin of experimental biology and medicine

authors： Lasukova TV,Maslov LN,Arbuzov AG,Burkova VN,Inisheva LI

更新日期：2015-04-01 00:00:00

abstract：:Human umbilical cord represents a source of multipotent stromal cells of a supreme therapeutic potential. The cells can be isolated from either fresh or cryopreserved umbilical cord tissues. DMSO is a cryoprotectant most commonly used for preservation of umbilical cord tissues; however, cyto- and genotoxicity of this ...

journal_title：Bulletin of experimental biology and medicine

authors： Arutyunyan IV,Strokova SО,Makarov АV,Mullabaeva SМ,Elchaninov АV,Lokhonina АV,Abramov АА,Fatkhudinov ТK

更新日期：2018-11-01 00:00:00