New aspects of technical testing of intravascular stents.

abstract：:Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary oral administration of glycine almost completely prevented th...

journal_title：Bulletin of experimental biology and medicine

authors： Selin AA,Lobysheva NV,Vorontsova ON,Tonshin AA,Yaguzhinsky LS,Nartsissov YR

更新日期：2012-05-01 00:00:00

abstract：:We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Naumova LA,Osipova ON,Klinnikova MG

更新日期：2019-04-01 00:00:00

abstract：:Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP-syndrome. Different disturbances of ...

journal_title：Bulletin of experimental biology and medicine

authors： Tereshchenko LV,Yudin AG,Kuznetsov Y,Latanov AV,Shul'govskii VV

更新日期：2002-02-01 00:00:00

abstract：:We studied the effect of vasopressin analogue desglycinamide-arginine-vasopressin on changes in platelet hemostasis produced by intragastric administration of Ticlid or clopidogrel (inhibitors of ADP-induced platelet aggregation). Intranasal administration of the peptide under conditions of hemorrhagic diathesis produ...

journal_title：Bulletin of experimental biology and medicine

authors： Golubeva MG,Grigoreva ME,Smirnova MP

更新日期：2005-08-01 00:00:00

abstract：:In experiments on narcotized rats, BP in the left femoral artery as well as local electrical potential and electrical impedance of the symmetric segment of the right femoral artery were simultaneously recorded in situ with two extracellular nonpolarizable Ag/AgCl electrodes located along the artery at a distance of 3 ...

journal_title：Bulletin of experimental biology and medicine

authors： Revenko SV,Tikhomirova LN,Nesterov AV,Tarakanov IA

更新日期：2018-04-01 00:00:00

abstract：:Intraperitoneal injections of hexavalent chromium (sodium bichromate) in the concentrations of 0.025 μg/kg (10-fold lower than MAC; group 1) and 2.5 μg/kg (10-fold higher than MAC; group 2) to rats in a subacute experiment caused dose-dependent morphological changes in the thymus: increased the counts of cells in a st...

journal_title：Bulletin of experimental biology and medicine

authors： Zhumabaeva AN,Zarishnyak NV,Bekmukhambetov EZh

更新日期：2014-02-01 00:00:00

abstract：:The level of expression of CD11b and HLA-DR surface molecules on monocyte-like THP-1 cells increased significantly as a result of transmigration of these cells through a monolayer of endothelial cells. The expression of all studied markers (CD11b, HLA-DR, and CD-14) increased significantly after transendothelial migra...

journal_title：Bulletin of experimental biology and medicine

authors： Starikova EA,Sokolov DI,Chernova AA,Freidlin IS

更新日期：2008-11-01 00:00:00

abstract：:We studied the effect of sodium hydrosulfite (NaHS), a donor of hydrogen sulfide (H2S), on spontaneous contractive activity of isolated preparations of rat stomach and jejunum under isometric conditions. NaHS in concentrations of 10-200 μM reduced the amplitude, tonic tension, and frequency of contractions of the prep...

journal_title：Bulletin of experimental biology and medicine

authors： Shafigullin MY,Zefirov RA,Sabirullina GI,Zefirov AL,Sitdikova GF

更新日期：2014-07-01 00:00:00

abstract：:Induction of direct cell death is one of the mechanisms of the antitumor effect of GD2-specific antibodies used for the therapy of high-risk neuroblastoma. The mechanisms of the cytotoxic signal triggered by antibody binding to GD2 ganglioside on the surface of the tumor cell remain insufficiently studied. Using inhib...

journal_title：Bulletin of experimental biology and medicine

authors： Doronin II,Kholodenko IV,Zubareva AA,Yarygin KN,Deev SM,Kholodenko RV

更新日期：2019-02-01 00:00:00

abstract：:The study included 52 patients at a high risk of thromboembolic complications, with permanent atrial fibrillation. All patients were treated with acenocoumarol for 6 months and the incidence of hemorrhages was evaluated in all of them. All patients were genotyped by CYP2C9 and VKORC1. The presence of CYP2C9*2 and CYP2...

journal_title：Bulletin of experimental biology and medicine

authors： Sychev DV,Ignatyev IV,Emelyanov NV,Milovanova VV,Kossovskaya AV,Kukes IV,Tashenova AI,Kukes VG

更新日期：2012-10-01 00:00:00

abstract：:The inotropic response of the myocardium to extrasystolic treatment was studied on isolated perfused papillary muscles from rats with postinfarction cardiosclerosis. The development of postinfarction cardiosclerosis was accompanied by a decrease in myocardial excitability. The amplitude of extrasystolic contractions i...

journal_title：Bulletin of experimental biology and medicine

authors： Kondrat'eva DS,Afanas'ev SA,Falaleeva LP,Shakhov VP

更新日期：2005-06-01 00:00:00

abstract：:We studied the effect of UV light (240-390 nm) in doses of 75.5-4530 J/m(2) on functional properties and level of intracellular messengers (cAMP, Ca(2+), NO) in lymphocytic cells of the peripheral blood. Correcting effects of UV light in a dose of 151 J/m(2) on cytotoxic activity of lymphocytes against Ehrlich ascetic...

journal_title：Bulletin of experimental biology and medicine

authors： Nakvasina MA,Lidokhova OV,Popova LI,Trubitsyna MS,Artyukhov VG

更新日期：2011-04-01 00:00:00

abstract：:We studied mesenchymal stem cells from human bone marrow, adipose tissue, skin, placenta, and thymus. Morphological study and cytofluorometrical analysis by the main marker genes (CD10, CD13, CD31, CD44, CD90, CD105) were carried out. Mesemchymal stem cells of the studied tissues during isolation and culturing were mo...

journal_title：Bulletin of experimental biology and medicine

authors： Musina RA,Bekchanova ES,Sukhikh GT

更新日期：2005-04-01 00:00:00

abstract：:Comparative analysis of the state of the thymus, activity of cell component of the immune system, and open field behavior of Wistar and OXYS rats showed early involution of the thymus in OXYS rats. By morphological picture this involution corresponded to accidental involution and was paralleled by low level of delayed...

journal_title：Bulletin of experimental biology and medicine

authors： Markova EV,Obukhova LA,Kolosova NG

更新日期：2003-12-01 00:00:00

abstract：:The incidence of mutations in the BRCA1 and BRCA2 genes in the studied sampling of 74 patients with ovarian cancer was 19%. The incidence of mutations in the Russian sampling of patients, formed without consideration for the family history, is one of the highest in European countries. Retrospective analysis showed tha...

journal_title：Bulletin of experimental biology and medicine

authors： Smirnova TY,Pospekhova NI,Lyubchenko LN,Tjulandin SA,Gar'kavtseva RF,Ginter EK,Karpukhin AV

更新日期：2007-07-01 00:00:00

abstract：:The levels of himantane and its metabolites in daily urine and feces of rats were measured after intraperitoneal and oral dose of 25 mg/kg. The injected dose of the initial substance and 1.3% its metabolites were eliminated with excrements within 24 h after administration via both routes 0.23%. ...

journal_title：Bulletin of experimental biology and medicine

authors： Litvin EA,Bastrygin DV,Kolyvanov GB,Alekseyev KV,Zherdev VP

更新日期：2012-08-01 00:00:00

abstract：:Studies of the molecular mechanisms of esophageal cancer development have to be carried out on sufficient amount of tumor material, obtained under conditions of controlled exposure to carcinogenic factors. Esophageal cancer models on laboratory animals serve an indispensable source of this material. One of these model...

journal_title：Bulletin of experimental biology and medicine

authors： Shubin AV,Lesovaya EA,Kirsanov KI,Antoshina EE,Trukhanova LS,Gorkova TG,Belitsky GA,Yakubovskaya MG,Demidyuk IV

更新日期：2018-03-01 00:00:00

abstract：:We studied the effect of apolipoprotein A-I-tetrahydrocortisone complex on (14)C glucose absorption and lactate accumulation and on the rate of protein biosynthesis in isolated rat hepatocytes. The presence of apolipoprotein A-I-tetrahydrocortisone complex in the incubation medium increased absorption of labeled gluco...

journal_title：Bulletin of experimental biology and medicine

authors： Sumenkova DV,Knyazev RA,Guschya RS,Polyakov LM,Panin LE

更新日期：2009-08-01 00:00:00

abstract：:We studied the effect of adrenal cortex hormone dehydroepiandrosterone sulfate on maturation and functional activity of interferon-alpha-induced dendritic cells. Dehydroepiandrosterone sulfate stimulated differentiation and maturation of interferon-alpha-induced dendritic cell, which manifested in a decrease in the nu...

journal_title：Bulletin of experimental biology and medicine

authors： Leplina OY,Tikhonova MA,Sakchno LV,Tyrinova TV,Ostanin AA,Chernykh ER

更新日期：2009-07-01 00:00:00

abstract：:We studied the effects of potentiated antibodies to morphine and mu-opioid receptors on animal behavior in the forced swimming test and reaction of light avoidance after morphine withdrawal. Antibodies to morphine normalized behavioral characteristics in the forced swimming test, while antibodies to mu-opioid receptor...

journal_title：Bulletin of experimental biology and medicine

authors： Pavlov IF,Epstein OI,Shtark MB

更新日期：2003-01-01 00:00:00

abstract：:Coagulation and optical (based on chromogenic substrate) methods were employed to examine antithrombin activity of erythrocytes and erythrocyte-derived microvesicles isolated days 7, 14, 21, and 28 on erythrocyte storage. The erythrocyte-derived microvesicles decelerated fibrin clot formation from fibrinogen in the pr...

journal_title：Bulletin of experimental biology and medicine

authors： Levin GY,Sukhareva EG

更新日期：2017-04-01 00:00:00

abstract：:We studied anticonvulsant effects of combined treatment with citicoline, a nootropic substance with neuroregenerative and neuroprotective activities, and valproate, an antiepileptic agent widely used in the treatment of epilepsy, on the model of pentylenetetrazole-induced (75 mg/kg, intraperitoneally) acute generalize...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova MN,Kuznetsova LV,Zin'kovskii KA,Klishina NV

更新日期：2016-02-01 00:00:00

abstract：:We studied reflection of artificially induced and amplified food motivation in impulse activity of the masticatory muscles during electrostimulation of "hunger center" of the lateral hypothalamus in the absence and presence of food. The threshold stimulation of the lateral hypothalamus in hungry and satiated animals i...

journal_title：Bulletin of experimental biology and medicine

authors： Ignatova JP,Kromin AA

更新日期：2012-04-01 00:00:00

abstract：:Behavioral responses of 90-day-old male offspring from female Wistar rats exposed to restraint stress during the last week of pregnancy were studied in the formalin test. Specific biphasic behavioral response characterized acute (phase 1) and persistent tonic pain (phase 2). The intensity of nociceptive responses (eva...

journal_title：Bulletin of experimental biology and medicine

authors： Butkevich IP

更新日期：2002-02-01 00:00:00

abstract：:We evaluated the concentration dependence and time dependence of the effect of nitroglycerine on intracellular content of cAMP, cGMP, and free Ca2+. It was shown that after norepinephrine stimulation, nitroglycerine exhibited calcium-blocking activity in lower concentrations (starting from 10(-7) M). Under conditions ...

journal_title：Bulletin of experimental biology and medicine

authors： Dukhanin AS,Shimanovskii NL

更新日期：2006-05-01 00:00:00

abstract：:More than 70% malignant mammary tumors contain steroid hormone receptors; this suggests the possibility of hormone therapy in the majority of patients with breast cancer (BC). The main cause of inefficiency of hormone therapy in BC is hormone resistance (tumor resistance to hormonal cytostatics). Here we discuss the m...

journal_title：Bulletin of experimental biology and medicine

authors： Scherbakov AM,Krasil'nikov MA,Kushlinskii NE

更新日期：2013-07-01 00:00:00

abstract：:Fibroblasts isolated from skin biopsy specimens from patients with genetic forms of Parkinson's disease, carriers of mutations in LRRK2 and PARK2 genes, and from a healthy volunteer were reprogrammed using lentiviral vectors into induced pluripotent stem cells (iPSC). iPSC were differentiated into neuron-like cells us...

journal_title：Bulletin of experimental biology and medicine

authors： Konovalova EV,Novosadova EV,Grivennikov IA,Illarioshkin SN

更新日期：2015-10-01 00:00:00

abstract：:Changes in cerebral neurogenesis provoked by ischemia and the effect of fluoxetine on this process were studied using a three-vessel occlusion model of global transient cerebral ischemia. The global transient cerebral ischemia was modeled on male Wistar rats by transient occlusion of three major vessels originating fr...

journal_title：Bulletin of experimental biology and medicine

authors： Khodanovich MY,Kisel' AA,Chernysheva GA,Smol'yakova VI,Savchenko RR,Plotnikov MB

更新日期：2016-07-01 00:00:00

abstract：:We studied biocompatibility and bioresorption of 3D-printed polylactide and polyglycolide tissue membranes. Ultrasound microscopy and histological examination showed that membranes fabricated of a copolymer of lactic and glycolic acids in a mass ratio of 1:9 are bioresorbed and have good biocompatibility with soft tis...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EV,Petronyuk YS,Guseynov NA,Tereshchuk SV,Popov AA,Volkov AV,Gorshenev VN,Olkhov AA,Levin VM,Dymnikov AB,Rodionov VE,Tumanyan GA,Ivashkevich SG,Bonartsev AP,Borozdkin LL

更新日期：2021-01-01 00:00:00

abstract：:We studied the formation and cytophysiological characteristics of polynuclear macrophages in primary cultures of peritoneal cells from C57Bl/6 mice. Production of reactive oxygen species and phagocytic activity in polynuclear macrophages were higher than in mononuclear macrophages. The formation of polynuclear macroph...

journal_title：Bulletin of experimental biology and medicine

authors： Arkhipov SA,Shkurupiy VA,Ijine DA,Ignatovich NV,Akhromenko ES,Arkhipova VV

更新日期：2008-12-01 00:00:00