Anxiety and predisposition to audiogenic epilepsy in rats of different genotypes.

abstract：:In patients with ovarian cancer, the colony-forming capacity and radiosensitivity of clonogenic tumor cells from the primary node and metastases (ascites) differed considerably. ...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova AI,Sychenkova NI,Konoplyannikov AG,Lepekhina LA,Kal'sina SS,Krikunova LI,Mardynskii YS

更新日期：2001-06-01 00:00:00

abstract：:Morphological and proliferative characteristics of cultured Vero and MDCK cells were compared after growth in nutrient media of the basis of enzymatic hydrolysates of rice flour proteins and soybean flour proteins or control media (DMEM and Axcevir-MDCK). These media had a strong stimulatory effect on the growth of cu...

journal_title：Bulletin of experimental biology and medicine

authors： Mazurkova NA,Ryabchikova EI,Troshkova GP,Getmanova TN,Sumkina TP,Shishkina LN,Sergeev AN

更新日期：2009-04-01 00:00:00

abstract：:We studied the effect of terahertz radiation at NO frequencies 150.176-150.664 GHz on gaseous and electrolyte composition of the blood in albino rats during stress. Partial or complete recovery of the studied parameters of blood gases and electrolytes in stressed animals was observed after 15- and 30-min terahertz irr...

journal_title：Bulletin of experimental biology and medicine

authors： Kirichuk VF,Tsymbal AA

更新日期：2010-12-01 00:00:00

abstract：:Effects of prenatal hyperhomocysteinemia on hypothalamic regulation of estrous cycles were studied in female rats. In mature rats exposed to prenatal hyperhomocysteinemia, changes in the catecholamine content in hypothalamic areas responsible for the formation of the preovulatory surge of gonadotropin-releasing hormon...

journal_title：Bulletin of experimental biology and medicine

authors： Arutyunyan AV,Zaloznyaya IV,Kerkeshko GO,Milyutina YP,Korenevskii AV

更新日期：2017-04-01 00:00:00

abstract：:We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4(+) T cells and an increase in the count of central CD8(+) memory T cells in these patients....

journal_title：Bulletin of experimental biology and medicine

authors： Korolevskaya LB,Shmagel KV,Saidakova EV,Shmagel NG,Slobodchikova SV,Chereshnev VA

更新日期：2016-06-01 00:00:00

abstract：:The effect of intravenous transplantation of mesenchymal stem cells on the recovery of cognitive functions was studied in Wistar-Kyoto rats after brain stroke induced by occlusion of the middle cerebral artery in the left hemisphere. Analysis 2 and 5 weeks after stroke showed that transplantation of mesenchymal stem c...

journal_title：Bulletin of experimental biology and medicine

authors： Sokolova IB,Fedotova OR,Zin'kova NN,Kruglyakov PV,Polyntsev DG

更新日期：2006-10-01 00:00:00

abstract：:Comparative analysis of the parameters of LPO, antioxidant defense (AOD), and the thiol/disulfide system was performed in fertile and infertile males of reproductive age carrying different genotypes of the glutathione system genes. Blood plasma, blood hemolysate, and ejaculate served as specimens for biochemical studi...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LI,Kurashova NA,Bairova TA,Dolgikh MI,Ershova OA,Natyaganova LV,Dashiev BG,Gutnik IN,Koroleva NV

更新日期：2017-07-01 00:00:00

abstract：:Intensive exercise triggers the cascade processes of body adaptation, including modulation of splisosome functioning, and can lead to modification of its activity and choice of alternative exons. We studied the effect of exercise of the maximum aerobic power on activation of transcription of genes involved in the spli...

journal_title：Bulletin of experimental biology and medicine

authors： Tonevitsky EA,Trushkin EV,Shkurnikov MU,Akimov EB,Sakharov DA

更新日期：2009-06-01 00:00:00

abstract：:Ultrastructural characteristics of cell populations in the gastric tube mucosa were studied after plastic surgery for benign esophageal disease. The foveolar epithelium mainly consisted of secretory active mucocytes with small changes in cytoplasmic organelles. Functionally immature parietal cells and gland cells in t...

journal_title：Bulletin of experimental biology and medicine

authors： Lapii GA,Nepomnyashchikh LM,Sudovykh IE,Kutepov AV,Govorkov RV

更新日期：2011-02-01 00:00:00

abstract：:We studied the effect of 10-week treatment with intranasal insulin (0.5 IU/day) on glucose tolerance, glucose utilization, lipid metabolism, functions of pancreatic β cells, and insulin system in the liver of rats with cafeteria diet-induced metabolic syndrome. The therapy reduced body weight and blood levels of insul...

journal_title：Bulletin of experimental biology and medicine

authors： Derkach KV,Ivantsov AO,Chistyakova OV,Sukhov IB,Buzanakov DM,Kulikova AA,Shpakov AO

更新日期：2017-06-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) plays the central role in the mechanisms of regulation of neurogenesis and neuroplasticity. Impairment of these mechanisms is considered as one of the main etiological factors of depression. Dimeric dipeptide mimetic of BDNF loop 4 bis-(N-monosuccinyl-l-seryl-l-lysine) hexameth...

journal_title：Bulletin of experimental biology and medicine

authors： Gudasheva TA,Povarnina PY,Seredenin SB

更新日期：2017-02-01 00:00:00

abstract：:Human recombinant erythropoietin adsorbed on poly(butyl)cyanoacrylate nanoparticles and administered intraperitoneally in a dose of 0.05 mg/kg exhibited a neuroprotective effect in experimental intracerebral posttraumatic hematomas (hemorrhagic stroke) and reduced animal mortality. Human recombinant erythropoietin, na...

journal_title：Bulletin of experimental biology and medicine

authors： Solev IN,Balabanyan VY,Volchek IA,Elizarova OS,Litvinova SA,Garibova TL,Voronina TA

更新日期：2013-06-01 00:00:00

abstract：:We studied the effect of sodium hydrosulfite (NaHS), a donor of hydrogen sulfide (H2S), on spontaneous contractive activity of isolated preparations of rat stomach and jejunum under isometric conditions. NaHS in concentrations of 10-200 μM reduced the amplitude, tonic tension, and frequency of contractions of the prep...

journal_title：Bulletin of experimental biology and medicine

authors： Shafigullin MY,Zefirov RA,Sabirullina GI,Zefirov AL,Sitdikova GF

更新日期：2014-07-01 00:00:00

abstract：:Stimulation of the labyrinth in rabbits and guinea pigs with ascending (cathode) or descending direct current (anode) induced deviation and nystagmus of the eyes, head turn and tilt, and other reactions. Anodization of both labyrinths was followed by the disappearance of reflexes, suppression of vestibular reactions t...

journal_title：Bulletin of experimental biology and medicine

authors： Gorgiladze GI

更新日期：2004-12-01 00:00:00

abstract：:Transplantation of human bone marrow mesenchymal stem cells is considered as a promising therapeutic approach to the therapy of many diseases. However, the problem of possible alterations of the properties of mesenchymal stem cells during their expansion in in vitro cultures before transplantation is not solved. In ou...

journal_title：Bulletin of experimental biology and medicine

authors： Grigorian AS,Kruglyakov PV,Taminkina UA,Efimova OA,Pendina AA,Voskresenskaya AV,Kuznetsova TV,Polyntsev DG

更新日期：2010-12-01 00:00:00

abstract：:We revealed an antimetastatic effect of thymus-dependent corpuscular antigen (sheep erythrocytes) injected intravenously or intraperitoneally in sensitizing or high doses alone or in a complex with a course dose of cyclophosphamide to C57Bl/6 mice with Lewis carcinoma. Injection of the antigen appreciably reduced the ...

journal_title：Bulletin of experimental biology and medicine

authors： Mosienko MD,Mosienko VS,Solyanik GI,Kovalenko NG

更新日期：2004-06-01 00:00:00

abstract：:We studied anti-ischemic activity of n-tyrozol under conditions of repeated transient myocardial ischemia in rats caused by repeated (5×3 min) occlusion of the left coronary artery. n-Tyrozol administered intraperitoneally in a dose of 20 mg/kg daily over 4 days before the ischemia modeling (the last injection 15 min ...

journal_title：Bulletin of experimental biology and medicine

authors： Plotnikov MB,Chernysheva GA,Smol'yakova VI,Plotnikova TM,Sysolyatin SV,Kryukov YA

更新日期：2018-09-01 00:00:00

abstract：:A stable preparation of agaricinic acid nanoparticles was obtained. The mean hydrodynamic size of nanoparticles according to photon correlation spectroscopy was 200 nm and zeta potential was -57 mV. Cytotoxic activity of agaricinic acid nanoparticles against human HepG2 hepatoma cells was evaluated. Nanoparticles with...

journal_title：Bulletin of experimental biology and medicine

authors： Gudkova OI,Demchenko AG,Shvets AV,Kuryakov VN,Sedyakina NE,Lyundup AV,Feldman NB,Gromovykh TI,Lutsenko SV

更新日期：2020-08-01 00:00:00

abstract：:Voltage clamp and concentration jump experiments performed on Purkinje cells isolated from rat cerebellum showed that novel imidazobenzoimidazole derivative RU-353 increased the amplitude of GABA-activated chlorine current in a dose-dependent manner (EC50=15 microM for the currents activated by 1 microM GABA). RU-353 ...

journal_title：Bulletin of experimental biology and medicine

authors： Sharonova NI,Vorob'ev VS,Skrebitskii VG,Galenko-Yaroshevskii AP,Turovaya AY,Anisimova VA

更新日期：2005-09-01 00:00:00

abstract：:Study of the early embryogenesis process based on the previously suggested scheme of epithelial cambial cell work has shown that cambial (or stem) cells originate from the primary ectoderm and intensely express RhoA protein and slightly express Src kinase. This explains their stem properties and the absence of differe...

journal_title：Bulletin of experimental biology and medicine

authors： Yavisheva TM,Shcherbakov SD

更新日期：2012-05-01 00:00:00

abstract：:Presentation of visual and acoustic stimuli at a rate of 2-30 Hz modulated variability of the heart rhythm in volunteers. Potentation of vagal influences and a decrease in the contribution of ergotropic systems to the regulation of the heart rate were noted after 10 sessions of audiovisual stimulation. These changes w...

journal_title：Bulletin of experimental biology and medicine

authors： Zagulova DV,Podkopaeva TI,Vasil'ev VN,Medvedev MA

更新日期：2001-03-01 00:00:00

abstract：:A composition containing culture medium conditioned by mesenchymal stem cells and mesenchymal stem cell lysate improves biochemical parameters, reduces inflammation, and stimulates regenerative processes in the liver. ...

journal_title：Bulletin of experimental biology and medicine

authors： Khubutiya MSh,Temnov AA,Vagabov VA,Sklifas AN,Rogov KA,Zhgutov YA

更新日期：2015-05-01 00:00:00

abstract：:We studied the effect of bone marrow Thy 1,2+ cells on the growth of erythroid colonies and the role of monoamine in the regulation of proliferation and differentiation of erythroid precursor cells in experimental neuroses. Under conditions of conflict situation Thy 1,2+ cells stimulated the growth of erythropoietic p...

journal_title：Bulletin of experimental biology and medicine

authors： Skurikhin EG,Provalova NV,Pershina OV,Minakova MY

更新日期：2005-11-01 00:00:00

abstract：:Crystal aggregations of oral fluid from normal subjects and patients with type 2 diabetes mellitus were examined. Morphological signs characterizing crystal aggregations of salivary pools from patients with type 2 diabetes mellitus are described and classified. ...

journal_title：Bulletin of experimental biology and medicine

authors： Selifanova EI,Barer GM,Mkrtumyan AM,Denisov AB

更新日期：2004-09-01 00:00:00

abstract：:The hemostimulating effect of erythropoietin immobilized by the nanotechnology method of electron-beam synthesis was studied on the model of carboplatin-induced myelosuppression. Subcutaneous injection or oral administration of immobilized erythropoietin was followed by stimulation of erythropoiesis. The effect was mo...

journal_title：Bulletin of experimental biology and medicine

authors： Dygai AM,Zyuz'kov GN,Zhdanov VV,Artamonov AV,Bekarev AA,Madonov PG,Kinsht DN,Udut EV,Miroshnichenko LA,Khrichkova TY,Simanina EV,Stavrova LA,Chaikovskiy AV,Markova TS,Minakova MY

更新日期：2011-06-01 00:00:00

abstract：:Intraperitoneal injections of hexavalent chromium (sodium bichromate) in the concentrations of 0.025 μg/kg (10-fold lower than MAC; group 1) and 2.5 μg/kg (10-fold higher than MAC; group 2) to rats in a subacute experiment caused dose-dependent morphological changes in the thymus: increased the counts of cells in a st...

journal_title：Bulletin of experimental biology and medicine

authors： Zhumabaeva AN,Zarishnyak NV,Bekmukhambetov EZh

更新日期：2014-02-01 00:00:00

abstract：:Angiogenic action of compound GK-2, a dimeric dipeptide mimetic of loop 4 of nerve growth factor (NGF), was studied in in vitro and in vivo experiments. Experiments on human endothelial cell culture HUVEC showed that compound GK-2 significantly (p<0.05) stimulated the initial stage of angiogenesis, and its angiogenic ...

journal_title：Bulletin of experimental biology and medicine

authors： Kryzhanovskii SA,Antipova TA,Tsorin IB,Pekeldina ES,Stolyaruk VN,Nikolaev SV,Sorokina AV,Gudasheva TA,Seredenin SB

更新日期：2016-08-01 00:00:00

abstract：:Cytogenetic analysis of 13 mesenchymal stem cell cultures isolated from normal human adipose tissue was carried out at different stages of culturing. The incidence of chromosomes 6, 8, 11, and X aneuploidy and polyploidy was studied by fluorescent in situ hybridization. During the early passages, monosomal cells were ...

journal_title：Bulletin of experimental biology and medicine

authors： Buyanovskaya OA,Kuleshov NP,Nikitina VA,Voronina ES,Katosova LD,Bochkov NP

更新日期：2009-07-01 00:00:00

abstract：:The mechanisms of therapeutic resistance of human glioblastoma multiforme are analyzed. The authors make an attempt at systematization and scientific theoretical validation of new approaches to creation of biomedical cellular preparations, based on the oncoproteomic technologies, for personified therapy of the glial t...

journal_title：Bulletin of experimental biology and medicine

authors： Bryukhovetskii IS,Bryukhovetskii AS,Khotimchenko YS

更新日期：2015-04-01 00:00:00

abstract：:Glutathione S-transferase activity increased in rats with acute pancreatitis: 2.2 times on day 2, 2-fold on day 4, and 1.5 times on day 10. Inducers of microsomal enzymes aroclor 1254 and phenobarbital notably inhibited glutathione S-transferase activity in animals with experimental pancreatitis on days 2-4 of the dis...

journal_title：Bulletin of experimental biology and medicine

authors： Prokop'eva NV,Gulyaeva LF

更新日期：2000-05-01 00:00:00