Effects of immune complexes with different molecular weights on functional activity and intracellular pH of neutrophils exposed or not exposed to UV light.

abstract：:We studied the effects of single nucleotide polymorphisms in the promoter regions of matrix metalloproteinase genes rs1799750 (-1607dupG) MMP1, rs243865 (C-1306T) MMP2, rs3025058 (-1171dupA) MMP3, and rs11568818 (A-181G) MMP7 on the risk of varicose vein of the lower extremities in ethnical Russians, residents of the ...

journal_title：Bulletin of experimental biology and medicine

authors： Shadrina AS,Smetanina MA,Sevost'yanova KS,Shevela AI,Seliverstov EI,Zakharova EA,Voronina EN,Ilyukhin EA,Zolotukhin IA,Kirienko AI,Filipenko ML

更新日期：2017-09-01 00:00:00

abstract：:The parameters of thermal dependence of H+ transport into human erythrocytes in the presence of furosemide were measured. The relationship between these changes and function of band 3 protein of the erythrocyte membrane is discussed. ...

journal_title：Bulletin of experimental biology and medicine

authors： Mishchenko AA,Irzhak LI

更新日期：2004-07-01 00:00:00

abstract：:We studied changes in protein composition and their effects on convulsive activity in drug-induced and electrical kindling. Injection of protein fraction of brain extract from animals subjected to metronidazole-induced kindling to intact recipients reduced their sensitivity to the convulsant (i. e. increased the dose ...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova MN,Karganov MY,Klishina NY,Khlebnikova NN,Kryzhanovskii GN

更新日期：2002-06-01 00:00:00

abstract：:We studied the effect of 20 standard L-amino acids on proliferation of the nervous, cardiovascular, urogenital, digestive, and immune system tissues from young and old animals in organotypic cultures. The effect of amino acids on tissue culture proliferation depended on their origin and animal age. ...

journal_title：Bulletin of experimental biology and medicine

authors： Chalisova NI,Kontsevaya NE,Linkova NS,Pronyaeva VE,Chervyakova NA,Umnov RS,Benberin VV,Khavinson VH

更新日期：2013-08-01 00:00:00

abstract：:Homocysteine and homocysteic acid increased the stationary level of reactive oxygen species in rat lymphocytes, homocysteic acid being more potent in this respect. The effect of this compound was realized via ionotropic NMDA receptors and group III metabotropic glutamate receptors. Incubation of lymphocytes with homoc...

journal_title：Bulletin of experimental biology and medicine

authors： Vladychenskaya EA,Tyulina OV,Boldyrev AA

更新日期：2006-07-01 00:00:00

abstract：:A new phenomenon (or paradox) consisting in higher statistical stability of samples, for example, tremorograms, in a group of different subjects than in the same subject in unchanged homeostasis. At the same time, it turns out that 15 different subjects are more similar (statistically) to each other than one person to...

journal_title：Bulletin of experimental biology and medicine

authors： Zilov VG,Khadartsev AA,Eskov VM,Ilyashenko LK

更新日期：2019-08-01 00:00:00

abstract：:Plasma concentration of immune complexes and antibodies to serotonin and dopamine were higher in patients with Alzheimer's disease compared to mentally healthy volunteers of the same age. Plasma concentrations of antibodies to serotonin and dopamine decreased with the increase in the duration of this disease. ...

journal_title：Bulletin of experimental biology and medicine

authors： Davydova TV,Mikovskaya OI,Fomina VG,Voskresenskaya NI,Doronina OA

更新日期：2002-07-01 00:00:00

abstract：:Chronic intranasal administration of fibrillar structures of proinflammatory S100A9 protein impaired passive avoidance learning in old C57Bl/6 mice. Combined treatment with S100A9 fibrils and antibodies to glutamate was followed by an increase in horizontal locomotor activity of animals in the open-field test and did ...

journal_title：Bulletin of experimental biology and medicine

authors： Gruden MA,Davydova TV,Fomina VG,Vetrile LA,Morozova-Roche LA,Sewell RD

更新日期：2017-02-01 00:00:00

abstract：:The location and level of IL-8 and TGF-beta2 expression in the fimbrial compartment of fallopian tubes and IL-10 expression in the endometrium of women with pyoinflammatory adnexal diseases were studied by in situ hybridization. These diseases are associated with considerable changes in the levels of local production ...

journal_title：Bulletin of experimental biology and medicine

authors： Zhdanov AV,Kurbanova DF,Sosulina LY,Davydova MP,Ezhova LS,Sukhikh GT

更新日期：2003-03-01 00:00:00

abstract：:We demonstrated specific changes in platelet structure in different types of tuberculous process, in particular, shift in the proportion between alpha-granules, dense granules, different disorders in the mitochondrial and lysosomal apparatus, etc. The role of platelets in immune process is studied. Redistribution of a...

journal_title：Bulletin of experimental biology and medicine

authors： Khechinashvili GN,Khvitiya NG

更新日期：2004-11-01 00:00:00

abstract：:Local application of ointment with Bacillus spp. strain MG8 (15,000-20,000 living bacterial cells), isolated from permafrost specimens, on the skin wound of about 60 mm(2) stimulated the reparation processes in experimental mice. A possible mechanism stimulating the regeneration of the damaged tissues under the effect...

journal_title：Bulletin of experimental biology and medicine

authors： Kalenova LF,Novikova MA,Subbotin AM

更新日期：2015-02-01 00:00:00

abstract：:Morphological and histoenzymatic changes in cells of the spinal cord and spinal ganglia after epidural injection of a combination of prosidol with clonidine were studied on dogs. No pathological structural and metabolic changes in the nervous tissue were found after combined treatment with the test drugs. Higher activ...

journal_title：Bulletin of experimental biology and medicine

authors： Volchkov VA,Strashnov VI,Tomson VV,Boikova NV,Zaitsev AA

更新日期：2001-09-01 00:00:00

abstract：:Myocardial remodeling in SHR rats with age-related hypertrophy was characterized by elimination of cardiomyocytes, their hypertrophy, and marked increase in the volume of the connective tissue. The count of cardiomyocytes with contracture injuries and subsegmental contractures increased, and pronounced perivascular an...

journal_title：Bulletin of experimental biology and medicine

authors： Lushnikova EL,Nepomnyashchikh LM

更新日期：2003-02-01 00:00:00

abstract：:We studied regulation of hypoxanthine transport depending on its concentration in the culture medium. Caco-2 cells were differentiated on membrane filters to create a model of the intestine. Different hypoxanthine uptake on the apical and basolateral cell membranes was observed. The expression of SLC29 family genes en...

journal_title：Bulletin of experimental biology and medicine

authors： Senyavina NV,Tonevitskaya SA

更新日期：2015-11-01 00:00:00

abstract：:We studied the effect of ozonized physiological saline on phagocytic properties of polymorphonuclear neutrophilic leukocytes from dog blood. Intravenous infusion of the examined doses of ozonized saline stimulated phagocytosis. Repeated intravenous infusion (48 h after) of the same dose was followed by a significant d...

journal_title：Bulletin of experimental biology and medicine

authors： Volkhovskaya NB,Tkachenko SB,Belopolsky AA

更新日期：2008-11-01 00:00:00

abstract：:Tenoten is a new anxiolytic and antidepressant based on antibodies to brain-specific protein S-100B. Experimental studies demonstrated the effect of tenoten on mechanisms of neuronal plasticity and manifestations of higher nervous activity. Tenoten is clinically comparable with amitryptiline, sertraline, and phenazepa...

journal_title：Bulletin of experimental biology and medicine

authors： Duma SA,Shishkin SV

更新日期：2009-08-01 00:00:00

abstract：:We revealed an antimetastatic effect of thymus-dependent corpuscular antigen (sheep erythrocytes) injected intravenously or intraperitoneally in sensitizing or high doses alone or in a complex with a course dose of cyclophosphamide to C57Bl/6 mice with Lewis carcinoma. Injection of the antigen appreciably reduced the ...

journal_title：Bulletin of experimental biology and medicine

authors： Mosienko MD,Mosienko VS,Solyanik GI,Kovalenko NG

更新日期：2004-06-01 00:00:00

abstract：:Fucoidans isolated from Fucus evanescens and Laminaria cichorioides kelp can inhibit thrombin and factor Xa of the blood coagulation system. In rats, intravenous injection of fucoidans dose-dependently increased anticoagulant activity of the plasma. Fucoidans can form complexes with protamine sulfate. The observed qua...

journal_title：Bulletin of experimental biology and medicine

authors： Drozd NN,Tolstenkov AS,Makarov VA,Kuznetsova TA,Besednova NN,Shevchenko NM,Zvyagintseva TN

更新日期：2006-11-01 00:00:00

abstract：:Manifestations of hunger and satiation in myoelectric activity patterns in different portions of the stomach were studied in chronic experiments. The state of hunger manifested in the structure of temporal organization of slow electric activity of muscles in the stomach body and antrum in the form of bimodal distribut...

journal_title：Bulletin of experimental biology and medicine

authors： Kromin AA,Zenina OY

更新日期：2012-11-01 00:00:00

abstract：:The hydruric response to water load in Wistar rats and homozygous Brattleboro rats with a hereditary defect in the synthesis of vasopressin was studied under conditions of increased brain serotonin level. Serotonin prevented the reduction in reabsorption of osmotically free water in normal rats, but had no effect in v...

journal_title：Bulletin of experimental biology and medicine

authors： Ivanova LN,Kochkaeva LN,Melidi NN

更新日期：2006-02-01 00:00:00

abstract：:Here we addressed a question of whether gamma oscillations previously described in the whisker-related barrel cortex are a universal pattern of activity in the somatosensory cortex of newborn rats. Intracortical recording of local field potentials and action potentials in neurons using multisite silicon electrodes in ...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimova EV,Zakharov AV,Lebedeva YA,Inacio AR,Minlebaev MG,Sitdikova GF,Khazipov RN

更新日期：2014-01-01 00:00:00

abstract：:Study of the expression of type IV collagen by Lewis pulmonary carcinoma cells (PLMG-T, PLMG-M1, PLMG-M2) showed that these cells produce type IV collagen. The expression of type IV collagen in PLMG-T and PLMG-M2 cells approximately 2-fold surpassed that in PLMG-M1 cells. The number of active cells (synthesizing type ...

journal_title：Bulletin of experimental biology and medicine

authors： Gaenko GP,Khaidukov SV,Molotkovskii YG

更新日期：2004-01-01 00:00:00

abstract：:Activity and levels of protein and mRNA of 3-hydroxy-3-methyl-glutaryl-CoA reductase were estimated in rat liver after the administration of atorvastatin and simvastatin and their complexes with glycyrrhizic acid (atorvaglyzin and simvaglyzin). The amount of 3-hydroxy-3-methyl-glutaryl-CoA reductase protein in rats de...

journal_title：Bulletin of experimental biology and medicine

authors： Stakhneva EM,Vavilin VA,Ragino YI,Safronova OG,Shintyapina AB,Ivanova MV

更新日期：2013-11-01 00:00:00

abstract：:Digital simulation of disorders in the p53 and Mdm2 protein system, involved in repair of DNA defects and in many vital processes, including tumor formation, neurodegeneration, and aging, was carried out on the base of functional nonlinear octoparametric mathematical model. Stress situations were studied, associated w...

journal_title：Bulletin of experimental biology and medicine

authors： Voropaeva OF,Shokin YI,Nepomnyashchikh LM,Senchukova SR

更新日期：2014-08-01 00:00:00

abstract：:Morphological and proliferative characteristics of cultured Vero and MDCK cells were compared after growth in nutrient media of the basis of enzymatic hydrolysates of rice flour proteins and soybean flour proteins or control media (DMEM and Axcevir-MDCK). These media had a strong stimulatory effect on the growth of cu...

journal_title：Bulletin of experimental biology and medicine

authors： Mazurkova NA,Ryabchikova EI,Troshkova GP,Getmanova TN,Sumkina TP,Shishkina LN,Sergeev AN

更新日期：2009-04-01 00:00:00

abstract：:We performed comparative analysis of hemodynamic in the periodontal microcirculatory bed in adolescents with arterial hypertension (AH) and morphological changes in the periodontal tissues of in hypertensive ISIAH rats of comparable biological age. In the periodontal tissues of adolescents with hypertension, the blood...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LR,Darenskaya MA,Kolesnikova LI,Grebenkina LA,Korytov LI,Batoroev YK,Belinskaya EI,Mikhalevich IM,Kolesnikov SI

更新日期：2020-10-01 00:00:00

abstract：:Cytoplasmic Na/K imbalance induced by cytotoxic substances (ethylene glycol and cytochalasin B) was studied. Incubation in Dulbecco's medium with these cytotoxins caused changes in K and Na concentrations in the mouse two-cell embryo blastomer. The effects of both substances resulted in a drop of Na content in the emb...

journal_title：Bulletin of experimental biology and medicine

authors： Pogorelov AG,Goldshtein DV,Pogorelova VN

更新日期：2008-04-01 00:00:00

abstract：:We studied the effect of electroconvulsive therapy on cognitive functions in rats with depression-like disorder caused by exposure to ultrasound of varying frequency (20-45 kHz). Object recognition and Morris water-maze tests revealed no negative effects of the therapy on memory. Moreover, positive effect of therapy w...

journal_title：Bulletin of experimental biology and medicine

authors： Ushakova VM,Zubkov EA,Morozova AY,Gorlova AV,Pavlov DA,Inozemtsev AN,Chekhonin VP

更新日期：2017-09-01 00:00:00

abstract：:Crossbred CC57BR/Mv mice inherited tryptophan oxygenase gene and predisposition to alcohol consumption from parent BALB/c and C57BL mice, respectively. In CC57BR/Mv mice no relationships were found between alcohol consumption, tryptophan oxygenase activity, and single nucleotide substitutions in intron 6 of the TDO2 g...

journal_title：Bulletin of experimental biology and medicine

authors： Kaledin VI,Klimova NV,Vasil'ev GV,Ivanova EA,Vasil'eva ED,Il'nitskaya SI

更新日期：2003-10-01 00:00:00

abstract：:We studied changes in the blood cytokine profile of rats 3 h, 1 day, and 8 days after acute stress on the model of 24-h immobilization followed by LPS administration (100 μg/kg intraperitoneally). The concentration of proinflammatory cytokines (particularly of IL-1β and TNFα) significantly decreased at the early stage...

journal_title：Bulletin of experimental biology and medicine

authors： Abramova AY,Pertsov SS,Alekseeva IV,Nikenina EV,Kozlov AY,Chekhlov VV,Chukhnina ME

更新日期：2020-04-01 00:00:00