Biological activity of amino acids in organotypic tissue cultures.

abstract：:The levels of natural antibodies to β-endorphin, bradykinin, histamine, dopamine, and serotonin were measured in 271 cardiological patients in order to evaluate the severity of their clinical status. The patients were distributed into groups differing by the course of the pathological process. The levels of natural an...

journal_title：Bulletin of experimental biology and medicine

authors： Morozova VS,Petrochenko SN,Myagkova MA,Bachurin SO

更新日期：2017-05-01 00:00:00

abstract：:We studied the effects of calcitonin, parathyrin, and Ca(2+) channel antagonist isoptin and agonist Bay-K-8644 on glucose consumption by muscle (diaphragm) and adipose (epididymal) tissues and insulin-stimulated glucose consumption in vivo and in vitro. Calcitonin and parathyrin did not alter glucose consumption; para...

journal_title：Bulletin of experimental biology and medicine

authors： Butakova SS,Nozdrachev AD

更新日期：2009-08-01 00:00:00

abstract：:The myogenic differentiation capacity of prenatal mesenchymal stem cells from the main sites of hemopoiesis (bone marrow, thymus, liver, and spleen) was studied. Myogenesis was observed in all studied cell cultures except splenic mesenchymal stem cells. Differentiating cells from the thymus, bone marrow, and liver wer...

journal_title：Bulletin of experimental biology and medicine

authors： Gornostaeva SN,Rzhaninova AA,Gol'dstein DV

更新日期：2006-04-01 00:00:00

abstract：:We compared the effects of soluble products from the placenta obtained from women with normal pregnancy and pregnancy complicated by preeclampsia on cytokine secretion by THP-1 cells cultured on a 3D Matrigel scaffold. In the presence of soluble products from all placentas, the cells actively secreted IL-8, MCP-1, and...

journal_title：Bulletin of experimental biology and medicine

authors： Onokhina YS,L'vova TY,Tsitskarava DZ,Koren'kov DA,Sel'kov SA,Sokolov DI

更新日期：2014-02-01 00:00:00

abstract：:The relationship between the process of ethanol preference formation in rat pups periodically separated from mothers during the first half of the nest period and the intensity of maternal behavior of females was studied. The progeny of females with poor maternal behavior and/or separated from mothers is characterized ...

journal_title：Bulletin of experimental biology and medicine

authors： Isengulova AA,Kalmykova ZA,Miroshnichenko IV

更新日期：2009-04-01 00:00:00

abstract：:Study of the epidermocyte nuclear-nucleolar system in atopic dermatitis and lichen planus by computer morphometry of preparations stained with 50% AgNO3 showed an increase in their morphometric parameters, reflecting hyperregeneratory processes. ...

journal_title：Bulletin of experimental biology and medicine

authors： Sapuntsova SG,Tsygankov VI,Simkatcheva MV,Timoshin SS

更新日期：2007-09-01 00:00:00

abstract：:Plasma LDL content increased in rats with mild chronic heart failure, but decreased in animals with severe pathology. The lipid profile of β-adrenoceptor antagonists depended on their selectivity. The most selective antagonists of β-adrenoceptors had little effect on the lipid composition. Nonselective β-adrenoceptor ...

journal_title：Bulletin of experimental biology and medicine

authors： Sidorov AV

更新日期：2013-12-01 00:00:00

abstract：:Penetration of titanium dioxide nanoparticles into enterocytes after their administration into isolated loop of rat small intestine was shown in vivo by transmission electron microscopy. Using electron diffraction, titanium dioxide nanoparticles were identified in the apical regions of the cells under plasma membranes...

journal_title：Bulletin of experimental biology and medicine

authors： Onishchenko GE,Erokhina MV,Abramchuk SS,Shaitan KV,Raspopov RV,Smirnova VV,Vasilevskaya LS,Gmoshinski IV,Kirpichnikov MP,Tutelyan VA

更新日期：2012-12-01 00:00:00

abstract：:We studied secretory activity of adrenal zona fasciculata cells in pubertal rats exposed to low doses of endocrine disrupter DDT during prenatal and postnatal periods and only during postnatal period. In exposed animals, circulatory disturbances leading to degeneration and necrosis of cells as well as regeneration foc...

journal_title：Bulletin of experimental biology and medicine

authors： Yaglova NV,Tsomartova DA,Obernikhin SS,Nazimova SV,Yaglov VV

更新日期：2018-12-01 00:00:00

abstract：:A reproducible model of fetal liver regeneration was created. Resection of 20% liver was carried out in rat fetuses on day 17 of prenatal development. The organ weight was restored after 2 days at the expense of an increase in hepatocyte mitotic activity; cell hypertrophy was minor. After recovery, the cell compositio...

journal_title：Bulletin of experimental biology and medicine

authors： Elchaninov AV,Bolshakova GB

更新日期：2011-01-01 00:00:00

abstract：:Cardiac and plasma activities of marker lysosomal enzymes were studied in Wistar rats with metabolic (epinephrine) and occlusion (ligation of coronary arteries) myocardial infarction. Activity of all examined lysosomal enzymes significantly increased in the myocardium and blood plasma starting from the first day after...

journal_title：Bulletin of experimental biology and medicine

authors： Mayanskaya SD,Mayanskaya NN,Efremov AV,Yakobson GS

更新日期：2000-06-01 00:00:00

abstract：:Plasma concentration of immune complexes and antibodies to serotonin and dopamine were higher in patients with Alzheimer's disease compared to mentally healthy volunteers of the same age. Plasma concentrations of antibodies to serotonin and dopamine decreased with the increase in the duration of this disease. ...

journal_title：Bulletin of experimental biology and medicine

authors： Davydova TV,Mikovskaya OI,Fomina VG,Voskresenskaya NI,Doronina OA

更新日期：2002-07-01 00:00:00

abstract：:Comparative analysis of the state of the thymus, activity of cell component of the immune system, and open field behavior of Wistar and OXYS rats showed early involution of the thymus in OXYS rats. By morphological picture this involution corresponded to accidental involution and was paralleled by low level of delayed...

journal_title：Bulletin of experimental biology and medicine

authors： Markova EV,Obukhova LA,Kolosova NG

更新日期：2003-12-01 00:00:00

abstract：:One-month therapy with trimetazidine sharply decreased the content of free radical oxidation products, lipid peroxides and malonic dialdehyde, in atherogenic low-density lipoproteins in patients with coronary heart disease. Activity of glutathione peroxidase utilizing lipid peroxides in the plasma markedly increased d...

journal_title：Bulletin of experimental biology and medicine

authors： Tikhaze AK,Lankin VZ,Zharova EA,Kolycheva SV

更新日期：2000-10-01 00:00:00

abstract：:Using rat model of spinal cord contusion injury at TVIII, we compared the effectiveness of immediate single transplantation of human mononuclear umbilical cord blood cells transfected with pBud-VEGF-FGF2 plasmid and immediate direct injection of the same plasmid into the lesion area. The results suggest that the deliv...

journal_title：Bulletin of experimental biology and medicine

authors： Shaymardanova GF,Mukhamedshina YO,Salafutdinov II,Rizvanov AA,Chelyshev YA

更新日期：2013-02-01 00:00:00

abstract：:The effects of two DNA aptamers (oligonucleotides) 15TBA and 31TBA (15- and 31-mer thrombin-binding aptamers, respectively) on thrombin activity were studied. Both aptamers added to human plasma dose-dependently increased thrombin time (fibrin formation upon exposure to exogenous thrombin), prothrombin time (clotting ...

journal_title：Bulletin of experimental biology and medicine

authors： Dobrovolsky AB,Titaeva EV,Khaspekova SG,Spiridonova VA,Kopylov AM,Mazurov AV

更新日期：2009-07-01 00:00:00

abstract：:Non-clonal and clonal abnormal cells (hypodiploid, polyploid, and with chromosome aberrations) were detected by the G-method in the bone marrow and blood of the majority of patients with non-Hodgkin lymphomas before therapy. The manifestation of these abnormalities changed individually after treatment. The most incide...

journal_title：Bulletin of experimental biology and medicine

authors： Ankina MA,Zavitaeva TA,Panferova TA,Shakhtarina SV,Pavlov VV

更新日期：2007-02-01 00:00:00

abstract：:Enzyme immunoassays showed significantly elevated content of matrix metalloproteinase 7 and type 1 tissue inhibitor of metalloproteinases in tumors compared to adjacent histologically unchanged mucosa of patients with colorectal cancer; the levels of metalloproteinase 9 and type 4 tissue inhibitor of metalloproteinase...

journal_title：Bulletin of experimental biology and medicine

authors： Gershtein ES,Korotkova EA,Shcherbakov AM,Prorokov VV,Golovkov DA,Kushlinskii NE

更新日期：2007-04-01 00:00:00

abstract：:Cytoplasmic Na/K imbalance induced by cytotoxic substances (ethylene glycol and cytochalasin B) was studied. Incubation in Dulbecco's medium with these cytotoxins caused changes in K and Na concentrations in the mouse two-cell embryo blastomer. The effects of both substances resulted in a drop of Na content in the emb...

journal_title：Bulletin of experimental biology and medicine

authors： Pogorelov AG,Goldshtein DV,Pogorelova VN

更新日期：2008-04-01 00:00:00

abstract：:Local injection of 4 nmol moxonidine (unilaterally) into the rostroventrolateral medulla of spontaneously hypertensive rats (SHR-SP) decreased mean blood pressure and heart rate by 24+/-3 and 3+/-4%, respectively. Pretreatment with the I1/alpha2-receptor antagonist efaroxan abolished the moxonidine-induced decrease in...

journal_title：Bulletin of experimental biology and medicine

authors： Khokhlova ON,Murashev AN,Medvedev OS

更新日期：2001-04-01 00:00:00

abstract：:Cytochemical activity of succinate dehydrogenase and lactate dehydrogenase in blood lymphocytes, activity of hydroperoxides, MDA, and blood plasma antioxidants were studied in experimental animals during immobilization stress after preliminary injection of doxazosin. Preliminary adrenergic receptor blockade prevented ...

journal_title：Bulletin of experimental biology and medicine

authors： Vishnevskii EL,Vishnevskii AE,Shabel'nikova EI,Safronova ON,Dreval AA,Topchieva GV,Sukhorukov VS

更新日期：2004-11-01 00:00:00

abstract：:The cardioprotective effects of Ganoderma lucidum extract were examined in experiments with global ischemia (45 min) and reperfusion (30 min) of isolated and perfused rat heart. The course of preventive administration of the extract in a dose of 400 mg/kg for 15 days diminished necrotic death of cardiomyocytes and red...

journal_title：Bulletin of experimental biology and medicine

authors： Lasukova TV,Maslov LN,Arbuzov AG,Burkova VN,Inisheva LI

更新日期：2015-04-01 00:00:00

abstract：:We studied the effect of continuous vibration and treatment with licorice root (Glycyrrhiza glabra L.) on peripheral blood red cells in rabbits. Active substances of licorice root accelerated metabolism in cells of the bone marrow erythroid stem, enhanced compensatory reserve of the organism, and increased animal's re...

journal_title：Bulletin of experimental biology and medicine

authors： Adamyan TI,Gevorkyan ES,Minasyan SM,Oganesyan KR,Kirakosyan KA

更新日期：2005-08-01 00:00:00

abstract：:We studied carbohydrate specificity and isotypes of antibodies to BSA-conjugated tetrasaccharide, a repeating unit of the capsular polysaccharide of Streptococcus pneumoniae serotype 14, in mouse polyclonal sera and hybridoma-synthesized products. Natural IgM antibodies to the tetrasaccharide containing epitopes simil...

journal_title：Bulletin of experimental biology and medicine

authors： Kurbatova ЕА,Yakovleva IV,Akhmatova EА,Sukhova ЕV,Yashunsky DV,Tsvetkov YE,Nifantiev NE

更新日期：2019-02-01 00:00:00

abstract：:We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Naumova LA,Osipova ON,Klinnikova MG

更新日期：2019-04-01 00:00:00

abstract：:We performed a comparative analysis of biological activity of Lys-Glu peptide and its amino acid constituents. It was established that Lys-Glu stimulated proliferation of splenic cells in organotypic culture, while the mixture of glutamic acid and lysine inhibited culture growth. Using the method of molecular docking,...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Tarnovskaya SI,Lin'kova NS,Chervyakova NA,Nichik TE,Elashkina EV,Chalisova NI

更新日期：2015-02-01 00:00:00

abstract：:Oxidative kidney injury was compared in newborn and adult rats under conditions of ischemia/reperfusion and in experimental model of systemic inflammation induced by endotoxin (LPS of bacterial cell wall) administration. Oxidative stress in the kidney accompanied both experimental models, but despite similar oxidative...

journal_title：Bulletin of experimental biology and medicine

authors： Pevzner IB,Pavlenko TA,Popkov VA,Andrianova NV,Zorova LD,Brezgunova AA,Zorov SD,Yankauskas SS,Silachev DN,Zorov DB,Plotnikov EY

更新日期：2018-06-01 00:00:00

abstract：:We studied ultrastructure of nuclear compartment in cardiomyocytes during regenerative and plastic insufficiency of the myocardium induced by anthracycline antibiotic daunomycin. A peculiarity of ultrastructural organization of cardiomyocyte nuclei under these conditions is almost complete disappearance of the heteroc...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh LM,Lushnikova EL,Semenov DE

更新日期：2000-12-01 00:00:00

abstract：:The efficiency of ascorbate and alpha-tocopherol as stabilizers of beta-carotene, which is widely used in complex therapy and prevention of some diseases accompanied by oxidative stress, was studied. The latency of induced beta-carotene oxidation linearly depends on ascorbate concentration, while steady-state rate non...

journal_title：Bulletin of experimental biology and medicine

authors： Kozachenko AI,Gurevich SM,Nagler LG

更新日期：2000-07-01 00:00:00

abstract：:The study compared the effects of phytococktail Bioritm-E (a multicomponent phytoadaptogen) and experimental preparation Skvaakan from the liver of Black Sea spurdog on systemic homeostasis, microcirculation, and blood lipid profile in 15 days of their daily administration. Skvaakan enhanced the platelet activity prod...

journal_title：Bulletin of experimental biology and medicine

authors： Datieva FS,Khetagurova LG

更新日期：2012-12-01 00:00:00