Expression of type IV collagen by Lewis pulmonary carcinoma cells.

Abstract:

:Study of the expression of type IV collagen by Lewis pulmonary carcinoma cells (PLMG-T, PLMG-M1, PLMG-M2) showed that these cells produce type IV collagen. The expression of type IV collagen in PLMG-T and PLMG-M2 cells approximately 2-fold surpassed that in PLMG-M1 cells. The number of active cells (synthesizing type IV collagen) in PLMG-M1 culture was 1.6 and 2.2 times lower than in PLMG-M2 and PLMG-T cultures, respectively. It was found that cell culture medium modulated expression of type IV collagen and this effect was mediated via cell receptors.

journal_name

Bull Exp Biol Med

authors

Gaenko GP,Khaidukov SV,Molotkovskii YG

doi

10.1023/b:bebm.0000024390.08829.ee

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

67-9

issue

1

eissn

0007-4888

issn

1573-8221

pii

doi

journal_volume

137

pub_type

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