Abstract:
:Cytoplasmic Na/K imbalance induced by cytotoxic substances (ethylene glycol and cytochalasin B) was studied. Incubation in Dulbecco's medium with these cytotoxins caused changes in K and Na concentrations in the mouse two-cell embryo blastomer. The effects of both substances resulted in a drop of Na content in the embryonic cell. Washing from cytochalasin B restored the initial Na/K balance in the cytoplasm. Possible adaptive mechanisms involved in the regulation of intracellular ionic homeostasis are discussed.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Pogorelov AG,Goldshtein DV,Pogorelova VNdoi
10.1007/s10517-008-0134-2subject
Has Abstractpub_date
2008-04-01 00:00:00pages
531-4issue
4eissn
0007-4888issn
1573-8221pii
doijournal_volume
145pub_type
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