Abstract：
:The effect of Dicarbamin preparation on hemopoiesis suppressed with cyclophosphamide was studied in animal experiments. It was shown that Dicarbamin produced a protective effect on granulocytic hemopoietic steam. This property of the preparation is determined by both protection of immature granulocytic cells at early terms after cytostatic treatment and more active maturation of neutrophils in the bone marrow due to enhanced secretion of humoral factors by elements of hemopoietic environment at late terms of the experiment.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Nebolsin VE,Zhdanov VV,Zyuzkov GN,Udut EV,Khrichkova TY,Simanina EV,Stavrova LA,Miroshnichenko LA,Chaikovskiy AV,Dygai AMdoi
10.1007/s10517-011-1138-xsubject
Has Abstractpub_date
2011-01-01 00:00:00pages
343-7issue
3eissn
0007-4888issn
1573-8221journal_volume
150pub_type
杂志文章abstract：:Single intramuscular injection of selective of NMDA receptor blocker memantine in the maximum dose of 20 mg/kg prevented the development of acute generalized tonic-clonic kainate seizures in 60% rats, but did not alleviate clonic kainate seizures and prevented chronic kainate lethality in only 30% rats. Intramuscular ...
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