Abstract:
:The effect of intravenous urography (IVU) on the excretion rate and precipitation of Tamm-Horsfall glycoprotein (THG) has been evaluated in 19 patients. Urine samples were collected immediately before the administration of contrast medium (U1) and then during the period of the excretion urogram (U2). The urinary THG: creatinine clearance ratio decreased in 15 patients by a mean of 28.2% (range 2.9-70.8) and increased in four by a mean of 22.8% (range 13.5-36.4). In 18 of 19 patients the amount of THG precipitated following the IVU decreased from an average of 75.6% of the total in U1 (range 2.2-100) to 19.5% (range 2.0-59) in U2. In the one exception the fraction precipitated was only 2.2% in U1 and 2.5% in U2. It is concluded that during routine IVU there is no marked increase in the excretion rate of THG. More importantly, the percentage of THG precipitated actually decreases.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Dawnay AB,Thornley C,Nockler I,Webb JA,Cattell WRdoi
10.1097/00004424-198501000-00014subject
Has Abstractpub_date
1985-01-01 00:00:00pages
53-7issue
1eissn
0020-9996issn
1536-0210journal_volume
20pub_type
杂志文章abstract:OBJECTIVE:To determine the prevalence of nephrogenic systemic fibrosis (NSF) in patients with chronic kidney disease (CKD) who have received gadopentetate dimeglumine. MATERIALS AND METHODS:We retrospectively studied all patients who underwent contrast-enhanced magnetic resonance imagings (CE-MRIs) between January 1, ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31819343ba
更新日期:2009-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors studied the incidence and distribution of orthopedic injuries sustained in Operation Desert Shield and Desert Storm by evaluating whether existing diagnostic imaging modalities were sufficient to diagnose the types of musculoskeletal injuries incurred. The authors also sought to det...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199703000-00006
更新日期:1997-03-01 00:00:00
abstract:INTRODUCTION:The aim of the present study was to evaluate the potential of high-resolution MRI at 2 Tesla (T) for direct noninvasive imaging of the aortic wall in a mouse model of atherosclerosis. MATERIAL AND METHODS:A specific mouse antenna was developed and sequence parameters were adjusted. T(1)- and T2-weighted i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000067491.31978.1c
更新日期:2003-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Iopromide is a new monomeric, nonionic contrast agent that exhibits low osmolality and low viscosity in high concentration in aqueous solutions. Double-blind, randomized clinical trials have established the efficacy, safety, and tolerance of iopromide for excretory urography, coronary angiograp...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-199405001-00015
更新日期:1994-05-01 00:00:00
abstract::Erythrocytes at various concentrations were examined with a sensitive A-mode ultrasonic scanner; simultaneous measurements were made under light microscopic control. Individual erythrocytes caused weak (about 1 dB) echoes while erythrocyte aggregates (ten to 100 cells) produced stronger echoes (up to 15 dB), grossly p...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198508000-00014
更新日期:1985-08-01 00:00:00
abstract::Skeletal abnormalities have been reported on numerous occasions in patients who have received high doses of vitamin A and its derivatives. Recently, a new derivative, isotretinoin (Accutane, Hoffman-LaRoche, Inc.), has become available for the treatment of cystic acne. Ninety-six patients treated for a minimum of four...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198601000-00007
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess the value of intravoxel incoherent motion and diffusion-weighted imaging for predicting the histologic grade of pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:Forty patients with surgically diagnosed PNETs who underwent preoperative magnetic resonance im...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000028
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS:A large, single-center retrospective population sur...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000431
更新日期:2018-04-01 00:00:00
abstract::Intravenous or intra-aortic injections of meglumine iothalamate in dogs indicate a slightly different tissue distribution and excretory pattern of the meglumine cation and the iothalamate anion. Differences in serum and urinary concentrations of these ions suggest some cellular penetration of the meglumine anion. In a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197507000-00004
更新日期:1975-07-01 00:00:00
abstract::Multiple intravenous injections of contrast media are used in radiology, but information regarding corresponding changes in the serum iodine concentrations and osmolality is lacking. We measured the changes in serum iodine concentration and serum osmolality in rabbits after a series of intravenous injections of contra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198703000-00007
更新日期:1987-03-01 00:00:00
abstract:OBJECTIVES:Volumetric magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU) is a completely noninvasive image-guided thermal ablation technique. Recently, there has been growing interest in the use of MR-HIFU for noninvasive ablation of malignant tumors. Of particular interest for noninvasive ablation...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182820257
更新日期:2013-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Very small dextran-coated magnetite particles were developed. These particles can be used either as immunospecific contrast agents for MRI by coupling to antibodies or as an interstitial contrast agent. METHODS:The particles were synthesized from iron chloride/dextran solutions. Size was evalu...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200009000-00006
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To investigate the correlation between intravoxel incoherent motion (IVIM) model-derived parameters and histologically determined microvascularity in pancreatic ductal adenocarcinomas (PDACs) and pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:From April 2013 to May 2014, 42 patients with mal...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000187
更新日期:2015-11-01 00:00:00
abstract::Compounds containing mobile protons can act as contrast agents by increasing the value of the term (1/12 - 1/11). The efficiency of this method is markedly pH- and field-dependent. There are many such compounds allowing a choice to be made based on the characteristics of the tissue or organ, magnetic field strength, a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198809001-00058
更新日期:1988-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Density of trabecular bone structures in human heel bones was assessed by 3D magnetic resonance (MR) gradient echo imaging (GEI) with multiple echoes. Different spatial resolutions were applied to investigate the influence of the pixel size on signal characteristics in GEI and to find suitable ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200007000-00001
更新日期:2000-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors studied premenopausal, perimenopausal, and postmenopausal women to determine if ultrasound bone velocity (UBV) on proximal phalanges of women reflect bone changes related to gonadal status and age. METHODS:A total of 166 healthy women-64 postmenopausal women (mean age 58.7 +/- 9.4 ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199701000-00011
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. MATERIALS AND METHODS:Twenty patients with known or suspected focal liver lesions underwent liver MRI usi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31816200b5
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:We sought to develop a robotic system for computed tomography (CT)-guided biopsy to validate the feasibility, accuracy, and efficacy of the system using phantom tests. MATERIALS AND METHODS:Ten peas (mean diameter 9.9+/-0.4 mm) embedded within a gel phantom were selected for biopsy. Once the best access was de...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000155285.05672.cf
更新日期:2005-04-01 00:00:00
abstract::Even though we have made much progress over the last decade, much still needs to be done. I am personally very pleased with the excellent management and authority of my coauthor, Joe Frank, in assuming the Acting Directorship of our DRRP. You will be hearing more from him in the immediate future about this research pr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199304001-00014
更新日期:1993-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Gd-DTPA is a well-characterized, safe contrast agent frequently used in magnetic resonance imaging (MRI) of the central nervous system. The purpose of this double-blind, comparative MRI study of brain, spine, trunk, and limbs was to evaluate the safety and efficacy of Gd-DOTA versus Gd-DTPA in ...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-199502000-00002
更新日期:1995-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors used gadolinium (Gd) chelate as a T1, T2, and T2* enhancing agent in reperfused myocardial infarction to compare the appearance of reperfused myocardial infarction on spin echo and gradient echo magnetic resonance (MR) sequences. METHODS:Rats (n = 28) were subjected to reperfused m...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199807000-00002
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:There is little published information regarding the efficacy of paclitaxel-coated balloon catheters except for the iopromide-containing formulation, and less is known about the kind of toxicity at overdose. The aim of our study was to assess 2 different paclitaxel matrix formulations on angioplasty balloon ca...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31820577df
更新日期:2011-04-01 00:00:00
abstract::In vitro incompatibilities between nine water-soluble contrast media and 21 intravascular pharmacologic agents were investigated using naked-eye observation and a centrifuge. Most of the previously reported incompatibilities were verified, and a few new incompatibilities were discovered: phentolamine mesylate with dia...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199201000-00008
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the ability of a flow-sensitive alternating inversion recovery-arterial spin labeling (FAIR-ASL) technique to track renal perfusion changes during pharmacologic and physiologic alterations in renal blood flow using microspheres as a gold standard. MATERIALS AND METHODS...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181f5e101
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine the gadolinium (Gd) concentration remaining in human bone tissue after administration of standard clinical doses of 2 Gd-based contrast agents: ProHance and Omniscan. MATERIALS AND METHODS:After administration of 0.1 mmol/kg of Gd chelate to patients undergoing hi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000186569.32408.95
更新日期:2006-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To compare gadobenate dimeglumine (Gd-BOPTA) with gadopentetate dimeglumine (Gd-DTPA) for magnetic resonance imaging of the liver. METHODS:The contrast agent Gd-BOPTA or Gd-DTPA was administered at a dose of 0.1 mmol/kg to 257 patients suspected of having malignant liver tumors. Dynamic phase ...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-200111000-00002
更新日期:2001-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors report on the development and preliminary validation of a technique for measuring contrast-to-noise ratio (CNR) at all points along selected vessel segments in the original three-dimensional magnetic resonance angiography (MRA) dataset. METHODS:Contrast-to-noise ratio dependencies ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199311000-00005
更新日期:1993-11-01 00:00:00
abstract::The morphologic changes in healthy rat kidneys (n = 102) were studied 2 or 48 hours after intravenous injection of 1 or 3 g iodine (I)/kg of high-osmolality diatrizoate, low-osmolality iopromide and iohexol, or iso-osmolality iotrolan, as well as after 0.2 or 0.6 g/kg of the high-osmolality magnetic resonance contrast...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199110000-00009
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/magnetic resonance (MR) (with and without diffusion-weighted imaging [DWI]) to F-FDG PET/computed tomography (CT), with regard to the assessment of nodal and extranodal involvement, in patients with Hodgkin lym...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000218
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the diagnostic performance and safety of magnetic resonance (MR) imaging-guided percutaneous mediastinal biopsy procedures using a 0.23-T open MR system with optical tracking navigation. MATERIALS AND METHODS:A retrospective analysis of 59 participants (38 males an...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/RLI.0b013e31827a4a17
更新日期:2013-06-01 00:00:00